Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Ivan T. Lee"'
Autor:
Ivan T. Lee, Raffael Nachbagauer, David Ensz, Howard Schwartz, Lizbeth Carmona, Kristi Schaefers, Andrei Avanesov, Daniel Stadlbauer, Carole Henry, Ren Chen, Wenmei Huang, Daniela Ramirez Schrempp, Jintanat Ananworanich, Robert Paris
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Despite vaccine availability, influenza remains a substantial global public health concern. Here, we report interim findings on the primary and secondary objectives of the safety, reactogenicity, and humoral immunogenicity of a quadrivalent
Externí odkaz:
https://doaj.org/article/234959adb1584b539256d7f99380c3d4
Autor:
Rebecca N. Bauer, Anastasia Teterina, Haridha Shivram, Jacqueline McBride, Carrie M. Rosenberger, Fang Cai, Min Bao, Larry Tsai, Oliver Gordon, Ivan T. Lee, Jeffrey J. Wallin, Danielle Porter, Kavita Juneja, Gregory Camus, Ivan O. Rosas, Steffen Wildum
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 6, Pp 1049-1062 (2023)
Abstract Observational studies have identified the potential prognostic value for severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) viral load and anti‐SARS‐CoV‐2 antibodies in coronavirus disease 2019 (COVID‐19). However, vi
Externí odkaz:
https://doaj.org/article/82e498d85ae64400857694f98dd85b56
Autor:
Ivan O. Rosas, Norbert Bräu, Michael Waters, Ronaldo C. Go, Atul Malhotra, Bradley D. Hunter, Sanjay Bhagani, Daniel Skiest, Sinisa Savic, Ivor S. Douglas, Julia Garcia-Diaz, Mariam S. Aziz, Nichola Cooper, Taryn Youngstein, Lorenzo Del Sorbo, David J. De La Zerda, Andrew Ustianowski, Antonio Cubillo Gracian, Kevin G. Blyth, Jordi Carratalà, Bruno François, Thomas Benfield, Derrick Haslem, Paolo Bonfanti, Cor H. van der Leest, Nidhi Rohatgi, Lothar Wiese, Charles Edouard Luyt, Rebecca N. Bauer, Fang Cai, Ivan T. Lee, Balpreet Matharu, Louis Metcalf, Steffen Wildum, Emily Graham, Larry Tsai, Min Bao
Publikováno v:
EClinicalMedicine, Vol 47, Iss , Pp 101409- (2022)
Summary: Background: In COVACTA, a randomised, placebo-controlled trial in patients hospitalised with coronavirus disease-19 (COVID-19), tocilizumab did not improve 28-day mortality, but shortened hospital and intensive care unit stay. Longer-term ef
Externí odkaz:
https://doaj.org/article/0cce1eb2d409455cafdb2877f5cbfad7
Autor:
Ivan T. Lee, Tsuguhisa Nakayama, Chien-Ting Wu, Yury Goltsev, Sizun Jiang, Phillip A. Gall, Chun-Kang Liao, Liang-Chun Shih, Christian M. Schürch, David R. McIlwain, Pauline Chu, Nicole A. Borchard, David Zarabanda, Sachi S. Dholakia, Angela Yang, Dayoung Kim, Han Chen, Tomoharu Kanie, Chia-Der Lin, Ming-Hsui Tsai, Katie M. Phillips, Raymond Kim, Jonathan B. Overdevest, Matthew A. Tyler, Carol H. Yan, Chih-Feng Lin, Yi-Tsen Lin, Da-Tian Bau, Gregory J. Tsay, Zara M. Patel, Yung-An Tsou, Alexandar Tzankov, Matthias S. Matter, Chih-Jaan Tai, Te-Huei Yeh, Peter H. Hwang, Garry P. Nolan, Jayakar V. Nayak, Peter K. Jackson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Understanding how SARS-CoV-2 gains initial entry into the human body is a key step towards the development of prophylaxes and therapeutics for COVID-19. Here, the authors show that ACE2, the receptor for SARS-CoV-2, is abundantly expressed in the mot
Externí odkaz:
https://doaj.org/article/46b19154257e4119b14a2d65b124b2f3
Autor:
Tsuguhisa Nakayama, Ivan T. Lee, Sizun Jiang, Matthias S. Matter, Carol H. Yan, Jonathan B. Overdevest, Chien-Ting Wu, Yury Goltsev, Liang-Chun Shih, Chun-Kang Liao, Bokai Zhu, Yunhao Bai, Peter Lidsky, Yinghong Xiao, David Zarabanda, Angela Yang, Meena Easwaran, Christian M. Schürch, Pauline Chu, Han Chen, Anna K. Stalder, David R. McIlwain, Nicole A. Borchard, Phillip A. Gall, Sachi S. Dholakia, Wei Le, Le Xu, Chih-Jaan Tai, Te-Huei Yeh, Elizabeth Erickson-Direnzo, Jason M. Duran, Kirsten D. Mertz, Peter H. Hwang, Jasmin D. Haslbauer, Peter K. Jackson, Thomas Menter, Raul Andino, Peter D. Canoll, Adam S. DeConde, Zara M. Patel, Alexandar Tzankov, Garry P. Nolan, Jayakar V. Nayak
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 10, Pp 100421- (2021)
Summary: Understanding viral tropism is an essential step toward reducing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission, decreasing mortality from coronavirus disease 2019 (COVID-19) and limiting opportunities for mutant s
Externí odkaz:
https://doaj.org/article/77b4712ecccd4b4dbf1453cd3b8dff8e
Autor:
Bokai Zhu, Shuxiao Chen, Yunhao Bai, Han Chen, Guanrui Liao, Nilanjan Mukherjee, Gustavo Vazquez, David R. McIlwain, Alexandar Tzankov, Ivan T. Lee, Matthias S. Matter, Yury Goltsev, Zongming Ma, Garry P. Nolan, Sizun Jiang
Publikováno v:
Nature Methods. 20:304-315
The ability to align individual cellular information from multiple experimental sources is fundamental for a systems-level understanding of biological processes. However, currently available tools are mainly designed for single-cell transcriptomics m
Autor:
Junjiao Yang, Yinghong Xiao, Peter V. Lidsky, Chien-Ting Wu, Luke R. Bonser, Shiming Peng, Miguel A. Garcia-Knight, Michel Tassetto, Chan-I Chung, Xiaoquan Li, Tsuguhisa Nakayama, Ivan T. Lee, Jayakar V. Nayak, Khadija Ghias, Kirsten L. Hargett, Brian K. Shoichet, David J. Erle, Peter K. Jackson, Raul Andino, Xiaokun Shu
Publikováno v:
Nat Microbiol
Nature microbiology, vol 8, iss 1
Nature microbiology, vol 8, iss 1
The coronavirus SARS-CoV-2 causes the severe disease COVID-19. SARS-CoV-2 infection is initiated by interaction of the viral spike protein and host receptor angiotensin-converting enzyme 2 (ACE2). We report an improved bright and reversible fluorogen
Autor:
Ivan T. Lee, Catherine A. Cosgrove, Patrick Moore, Claire Bethune, Rhiannon Nally, Marcin Bula, Philip A. Kalra, Rebecca Clark, Paul I. Dargan, Marta Boffito, Ray Sheridan, Ed Moran, Thomas C. Darton, Fiona Burns, Dinesh Saralaya, Christopher J. A. Duncan, Patrick Lillie, Alberto San Francisco Ramos, Eva Galiza, Paul T. Heath, Bethany Girard, Christy Parker, Dondi Rust, Shraddha Mehta, Elizabeth de Windt, Andrea Sutherland, Joanne E. Tomassini, Frank J. Dutko, Spyros Chalkias, Weiping Deng, Xing Chen, LaRee Tracy, Honghong Zhou, Jacqueline M. Miller, Rituparna Das
BackgroundOmicron-containing bivalent boosters are available worldwide. Results of a large, randomized, active-controlled study are presented.MethodsThis phase 3, randomized, observer-blind, active-controlled trial in the United Kingdom evaluated the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be411cd32fa14d0dade51f9918f29e63
https://doi.org/10.1101/2023.01.24.23284869
https://doi.org/10.1101/2023.01.24.23284869
Autor:
Katie M Phillips, Vidya K. Rao, Neelaysh Vukkadala, Zara M. Patel, Z Jason Qian, Jayakar V. Nayak, Ivan T. Lee, Peter H. Hwang, George H. Domb, Benjamin A. Pinsky, Kenji O. Mfuh, David Zarabanda, Matthew Hatter
Publikováno v:
The Laryngoscope
Objectives To determine the effect of povidone-iodine (PVP-I) nasal sprays on nasopharyngeal (NP) viral load as assessed by cycle threshold on quantitative polymerase chain reaction (qPCR) of SARS-CoV-2 in outpatients. Study design Three arm, triple
Autor:
Liang‐Chun Shih, Chun‐Chieh Hsu, Hsieh Bing‐Han, Ivan T. Lee, Yung‐An Tsou, Ming‐Hsui Tsai, Chih‐Jaan Tai
Publikováno v:
International Forum of Allergy & Rhinology. 12:318-320