Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Ivan Spasojevič"'
Autor:
Marina Stanić, Mima Jevtović, Snežana Kovačević, Milena Dimitrijević, Jelena Danilović Luković, Owen A. McIntosh, Bernd Zechmann, Alessandro Marco Lizzul, Ivan Spasojević, Jon K. Pittman
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Algal biomass is a viable source of chemicals and metabolites for various energy, nutritional, medicinal and agricultural uses. While stresses have commonly been used to induce metabolite accumulation in microalgae in attempts to enhance hig
Externí odkaz:
https://doaj.org/article/0557f754a84f43ebaf774b19210329ba
Autor:
Audrie Lin, Andrew N. Mertens, Md. Ziaur Rahman, Sophia T. Tan, Dora Il’yasova, Ivan Spasojevic, Shahjahan Ali, Christine P. Stewart, Lia C. H. Fernald, Lisa Kim, Liying Yan, Ann Meyer, Md. Rabiul Karim, Sunny Shahriar, Gabrielle Shuman, Benjamin F. Arnold, Alan E. Hubbard, Syeda L. Famida, Salma Akther, Md. Saheen Hossen, Palash Mutsuddi, Abul K. Shoab, Idan Shalev, Mahbubur Rahman, Leanne Unicomb, Christopher D. Heaney, Patricia Kariger, John M. Colford, Stephen P. Luby, Douglas A. Granger
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract A regulated stress response is essential for healthy child growth and development trajectories. We conducted a cluster-randomized trial in rural Bangladesh (funded by the Bill & Melinda Gates Foundation, ClinicalTrials.gov NCT01590095) to as
Externí odkaz:
https://doaj.org/article/91c66ba748f64ef4802f9ea905d3a130
Autor:
Seethalakshmi Hariharan, Benjamin T. Whitfield, Christopher J. Pirozzi, Matthew S. Waitkus, Michael C. Brown, Michelle L. Bowie, David M. Irvin, Kristen Roso, Rebecca Fuller, Janell Hostettler, Sharvari Dharmaiah, Emiley A. Gibson, Aaron Briley, Avani Mangoli, Casey Fraley, Mariah Shobande, Kevin Stevenson, Gao Zhang, Prit Benny Malgulwar, Hannah Roberts, Martin Roskoski, Ivan Spasojevic, Stephen T. Keir, Yiping He, Maria G. Castro, Jason T. Huse, David M. Ashley
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Stimulating the innate immune system has been explored as a therapeutic option for the treatment of gliomas. Inactivating mutations in ATRX, defining molecular alterations in IDH-mutant astrocytomas, have been implicated in dysfunctional imm
Externí odkaz:
https://doaj.org/article/93956c3a4d2c4721a96aa5db55f8df28
Autor:
Deborah K. Rose, Loren Bentley, Arnab Maity, Rachel L. Maguire, Antonio Planchart, Ivan Spasojevic, Andy J. Liu, John Thorp, Jr., Cathrine Hoyo
Publikováno v:
Heliyon, Vol 10, Iss 3, Pp e25578- (2024)
Background: Poor birth outcomes such as preterm birth/delivery disproportionately affect African Americans compared to White individuals. Reasons for this disparity are likely multifactorial, and include prenatal psychosocial stressors, and attendant
Externí odkaz:
https://doaj.org/article/f5a0149549674e76946f670e45e6de3b
Autor:
Angela Rivera, Won Young Lim, Eunchong Park, Patrick A. Dome, Michael J. Hoy, Ivan Spasojevic, Sheng Sun, Anna Floyd Averette, Sergio Pina-Oviedo, Praveen R. Juvvadi, William J. Steinbach, Maria Ciofani, Jiyong Hong, Joseph Heitman
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Fungal infections are of mounting global concern, and the current limited treatment arsenal poses challenges when treating such infections. In particular, infections by Cryptococcus neoformans are associated with high mortality, emphasizing
Externí odkaz:
https://doaj.org/article/ce0b324bccb346759ee1b133f5211833
Autor:
Ivan Bogdanović, Miloš Opačić, Vladimir Baščarević, Savo Raičević, Rosanda Ilić, Danica Grujičić, Ivan Spasojević, Aleksandar J. Ristić
Publikováno v:
Heliyon, Vol 9, Iss 10, Pp e20761- (2023)
Every third patient with intracranial meningioma develops seizures of poorly understood etiology. Tumor and peritumoral edema may exert mechanical pressure on the cortex that may affect mechano-gated potassium channels - KCNK2 and KCNK4. These channe
Externí odkaz:
https://doaj.org/article/75f50ff7630844a8bec0c8b893d8d964
Autor:
Xuan Li, Weina Duan, Li Du, Dongmei Chu, Peng Wang, Zhong Yang, Xingguang Qu, Zhenxing Yang, Ines Batinic-Haberle, Ivan Spasojevic, David S. Warner, James D. Crapo, Miriam M. Treggiari, Huaxin Sheng
Publikováno v:
Antioxidants, Vol 12, Iss 10, p 1861 (2023)
Endovascular mechanical thrombectomy, combined with a tissue plasminogen activator (t-PA), is efficacious as a standard care for qualifying ischemic stroke patients. However, > 50% of thrombectomy patients still have poor outcomes. Manganese porphyri
Externí odkaz:
https://doaj.org/article/cd7bd498d53b459a86835b675ccfbd52
Autor:
Sudha Sharma, Papori Sharma, Utsab Subedi, Susmita Bhattarai, Chloe Miller, Shrivats Manikandan, Ines Batinic-Haberle, Ivan Spasojevic, Hong Sun, Manikandan Panchatcharam, Sumitra Miriyala
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6159 (2023)
Myocardial ischemia-reperfusion injury (I/R) causes damage to cardiomyocytes through oxidative stress and apoptosis. We investigated the cardioprotective effects of MnTnBuOE-2-PyP5+ (BMX-001), a superoxide dismutase mimic, in an in vitro model of I/R
Externí odkaz:
https://doaj.org/article/bdc62df0428144ceb5c2810a61b9c681
Autor:
Wei Phin Tan, Andrew Chang, Steven C. Brousell, Dominic C. Grimberg, Joseph J. Fantony, Thomas A. Longo, Wiguins Etienne, Ivan Spasojevic, Paolo Maccarini, Brant A. Inman
Publikováno v:
International Journal of Hyperthermia, Vol 37, Iss 1, Pp 854-860 (2020)
Background Hyperthermia (heating to 43 °C) activates the innate immune system and improves bladder cancer chemosensitivity. Objective To evaluate the tissue penetration and safety of convective hyperthermia combined with intravesical mitomycin C (MM
Externí odkaz:
https://doaj.org/article/53a699b07a084134a563f09cf266d2d7
Autor:
Rita B. Soares, Rita Manguinhas, João G. Costa, Nuno Saraiva, Nuno Gil, Rafael Rosell, Sérgio P. Camões, Ines Batinic-Haberle, Ivan Spasojevic, Matilde Castro, Joana P. Miranda, Filipa Amaro, Joana Pinto, Ana S. Fernandes, Paula Guedes de Pinho, Nuno G. Oliveira
Publikováno v:
Antioxidants, Vol 11, Iss 11, p 2198 (2022)
The manganese(III) porphyrin MnTnHex-2-PyP5+ (MnTnHex) is a potent superoxide dismutase mimic and modulator of redox-based transcriptional activity that has been studied in the context of different human disease models, including cancer. Nevertheless
Externí odkaz:
https://doaj.org/article/67a72876692d4ab0aff01917ce527f4b