ROS release by PPARβ/δ-null fibroblasts reduces tumor load through epithelial antioxidant response

Autor: Chek Kun Tan, Jeremy Soon Kiat Chan, Ming Keat Sng, Ivan Shun Bo How, Jiapeng Chen, Nguan Soon Tan, Walter Wahli, Eddie Han Pin Tan

Publikováno v: Oncogene
Oncogene, Nature Publishing Group, 2018, ⟨10.1038/s41388-017-0109-8⟩
Oncogene, . (2018)
Oncogene, vol. 37, no. 15, pp. 2067-2078

Tumor stroma has an active role in the initiation, growth, and propagation of many tumor types by secreting growth factors and modulating redox status of the microenvironment. Although PPARβ/δ in fibroblasts was shown to modulate oxidative stress i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90dba0839e5e7cbe6786f08970b1780e
https://doi.org/10.1038/s41388-017-0109-8