Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Ivan S Alferiev"'
Autor:
Ivan S. Alferiev, Bahman Hooshdaran, Benjamin B. Pressly, Philip W. Zoltick, Stanley J. Stachelek, Michael Chorny, Robert J. Levy, Ilia Fishbein
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Impaired endothelialization of endovascular stents has been established as a major cause of in-stent restenosis and late stent thrombosis. Attempts to enhance endothelialization of inner stent surfaces by pre-seeding the stents with endothel
Externí odkaz:
https://doaj.org/article/444eb31192e64188aa9073126ce3c2d6
Autor:
Ivan S. Alferiev, Kehan Zhang, Zoë Folchman-Wagner, Richard F. Adamo, David T. Guerrero, Ilia Fishbein, Danielle Soberman, Robert J. Levy, Michael Chorny
Publikováno v:
Pharmaceutics, Vol 16, Iss 2, p 188 (2024)
The injury-triggered reocclusion (restenosis) of arteries treated with angioplasty to relieve atherosclerotic obstruction remains a challenge due to limitations of existing therapies. A combination of magnetic guidance and affinity-mediated arterial
Externí odkaz:
https://doaj.org/article/d13af531bd3646cbaf1ba7b8dd66ff7b
Autor:
Bahman Hooshdaran, Benjamin B. Pressly, Ivan S. Alferiev, Jonathan D. Smith, Philip W. Zoltick, Cory M. Tschabrunn, Robert L. Wilensky, Robert C. Gorman, Robert J. Levy, Ilia Fishbein
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract In-stent restenosis (ISR) complicates revascularization in the coronary and peripheral arteries. Apolipoprotein A1 (apoA1), the principal protein component of HDL possesses inherent anti-atherosclerotic and anti-restenotic properties. These
Externí odkaz:
https://doaj.org/article/724789fe477c49f884712f008b58a012
Publikováno v:
European Medical Journal, Vol 1, Iss 4, Pp 106-113 (2016)
The increasing sophistication of vascular stent design, especially devices that combine mechanical support with local drug delivery to the vascular wall, has resulted in major progress in the management of coronary and peripheral artery disease. This
Externí odkaz:
https://doaj.org/article/3c9ef3657b3041efbd4fbf63284426f5
Autor:
Garrett M. Brodeur, Michael Chorny, Ivan S. Alferiev, Benjamin B. Pressly, Danielle Soberman, Lauren M. Perry, Koumudi Naraparaju, Venkatadri Kolla, David T. Guerrero, Peng Guan, Ferro Nguyen
SN22 and SN38 pharmacokinetics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31fce3e1d16a0108c0ebf634aa035d58
https://doi.org/10.1158/0008-5472.22425546
https://doi.org/10.1158/0008-5472.22425546
Autor:
Garrett M. Brodeur, Michael Chorny, Ivan S. Alferiev, Benjamin B. Pressly, Danielle Soberman, Lauren M. Perry, Koumudi Naraparaju, Venkatadri Kolla, David T. Guerrero, Peng Guan, Ferro Nguyen
Blood counts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae9fc0bb8781e7f474bf13224da96895
https://doi.org/10.1158/0008-5472.22425555.v1
https://doi.org/10.1158/0008-5472.22425555.v1
Autor:
Garrett M. Brodeur, Michael Chorny, Ivan S. Alferiev, Benjamin B. Pressly, Danielle Soberman, Lauren M. Perry, Koumudi Naraparaju, Venkatadri Kolla, David T. Guerrero, Peng Guan, Ferro Nguyen
Liver function tests
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c75d2e049118c95eb6946d324fbb7f1
https://doi.org/10.1158/0008-5472.22425552
https://doi.org/10.1158/0008-5472.22425552
Autor:
Garrett M. Brodeur, Michael Chorny, Ivan S. Alferiev, Benjamin B. Pressly, Danielle Soberman, Lauren M. Perry, Koumudi Naraparaju, Venkatadri Kolla, David T. Guerrero, Peng Guan, Ferro Nguyen
Camptothecins are potent topoisomerase I inhibitors used to treat high-risk pediatric solid tumors, but they often show poor efficacy due to intrinsic or acquired chemoresistance. Here, we developed a multivalent, polymer-based prodrug of a structura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9270ded6a4fa0d5f81754ec6077a8e46
https://doi.org/10.1158/0008-5472.c.6512070.v1
https://doi.org/10.1158/0008-5472.c.6512070.v1
Autor:
Ilia Fishbein, Vaishali V Inamdar, Ivan S Alferiev, George Bratinov, Menekhem M. Zviman, Anna Yekhilevsky, Chandrasekaran Nagaswami, Kristin L. Gardiner, Robert J Levy, Stanley J Stachelek
BackgroundHypercholesterolemia (HC) has previously been shown to augment restenotic response in several animal models and humans. However, the mechanistic aspects of in-stent restenosis (ISR) on a hypercholesterolemic background, including potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1020134749a03e3614d55f9fbbf8a369
https://doi.org/10.1101/2023.02.27.530304
https://doi.org/10.1101/2023.02.27.530304
Publikováno v:
ACS Appl Polym Mater
Aliphatic polyesters are among materials most extensively used for producing biodegradable polymeric nanoparticles currently in development as delivery carriers and imaging agents for a range of biomedical applications. Their clinical translation req