Zobrazeno 1 - 10
of 339
pro vyhledávání: '"Ivan Rusyn"'
Autor:
Lucie C. Ford, Hsing-Chieh Lin, Yi-Hui Zhou, Fred A. Wright, Vijay K. Gombar, Alexander Sedykh, Ruchir R. Shah, Weihsueh A. Chiu, Ivan Rusyn
Publikováno v:
Human Genomics, Vol 18, Iss 1, Pp 1-23 (2024)
Abstract Per- and poly-fluoroalkyl substances (PFAS) are emerging contaminants of concern because of their wide use, persistence, and potential to be hazardous to both humans and the environment. Several PFAS have been designated as substances of con
Externí odkaz:
https://doaj.org/article/f47bcede66d34ab4b2df16aa5b31cf55
Autor:
En-Hsuan Lu, Fabian A. Grimm, Ivan Rusyn, Sarah De Saeger, Marthe De Boevre, Weihsueh A. Chiu
Publikováno v:
Environment International, Vol 182, Iss , Pp 108326- (2023)
Deoxynivalenol (DON) is a mycotoxin frequently observed in cereals and cereal-based foods, with reported toxicological effects including reduced body weight, immunotoxicity and reproductive defects. The European Food Safety Authority used traditional
Externí odkaz:
https://doaj.org/article/2ec8623911964082b38ba1083829709e
Autor:
Volodymyr P. Tryndyak, Rose A. Willett, Mark I. Avigan, Arun J. Sanyal, Frederick A. Beland, Ivan Rusyn, Igor P. Pogribny
Publikováno v:
Epigenetics, Vol 17, Iss 11, Pp 1462-1476 (2022)
Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent chronic liver disease, and patient susceptibility to its onset and progression is influenced by several factors. In this study, we investigated whether altered hepatic DNA methylation in
Externí odkaz:
https://doaj.org/article/c8f998f36f854dbc86f10cb401c5e178
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract Neurodegenerative diseases and neurotraumatic injuries are typically age-associated disorders that can reduce neuron survival, neurite outgrowth, and synaptic plasticity leading to loss of cognitive capacity, executive function, and motor co
Externí odkaz:
https://doaj.org/article/04b455db2672409ab634a56cbb9118f8
Autor:
Alicia Y. Lim, Yuki Kato, Courtney Sakolish, Alan Valdiviezo, Gang Han, Piyush Bajaj, Jason Stanko, Stephen S. Ferguson, Remi Villenave, Philip Hewitt, Rhiannon N. Hardwick, Ivan Rusyn
Publikováno v:
Bioengineering, Vol 10, Iss 10, p 1195 (2023)
The liver is one of the key organs for exogenous and endogenous metabolism and is often a target for drug- and chemical-driven toxicity. A wide range of experimental approaches has been established to model and characterize the mechanisms of drug- an
Externí odkaz:
https://doaj.org/article/a18304e2256b45029ba33d462bd66feb
Autor:
Kseniia Trofymchuk, Oleksandr Geychenko, Roman Soloviy, Taras Dyatlik, Helga Dyatlik, Valentyn Synii, Ivan Rusyn
Publikováno v:
Богословські роздуми: Східноєвропейський журнал богословʼя, Vol 20, Iss 2 (2023)
Externí odkaz:
https://doaj.org/article/3eaf42c34edd4118b387a3a50b65e039
Autor:
Alexandra C. Cordova, William D. Klaren, Lucie C. Ford, Fabian A. Grimm, Erin S. Baker, Yi-Hui Zhou, Fred A. Wright, Ivan Rusyn
Publikováno v:
Toxics, Vol 11, Iss 7, p 586 (2023)
Human cell-based test methods can be used to evaluate potential hazards of mixtures and products of petroleum refining (“unknown or variable composition, complex reaction products, or biological materials” substances, UVCBs). Analyses of bioactiv
Externí odkaz:
https://doaj.org/article/f9599d4b1d4744b2b10ad3a3b4d6c3ac
Autor:
Josepmaria Argemi, Maria U. Latasa, Stephen R. Atkinson, Ilya O. Blokhin, Veronica Massey, Joel P. Gue, Joaquin Cabezas, Juan J. Lozano, Derek Van Booven, Aaron Bell, Sheng Cao, Lawrence A. Vernetti, Juan P. Arab, Meritxell Ventura-Cots, Lia R. Edmunds, Constantino Fondevila, Peter Stärkel, Laurent Dubuquoy, Alexandre Louvet, Gemma Odena, Juan L. Gomez, Tomas Aragon, Jose Altamirano, Juan Caballeria, Michael J. Jurczak, D. Lansing Taylor, Carmen Berasain, Claes Wahlestedt, Satdarshan P. Monga, Marsha Y. Morgan, Pau Sancho-Bru, Philippe Mathurin, Shinji Furuya, Carolin Lackner, Ivan Rusyn, Vijay H. Shah, Mark R. Thursz, Jelena Mann, Matias A. Avila, Ramon Bataller
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/65a267dd546740ec9b7190c3e67982ab
Autor:
Alexandra C. Cordova, Lucie C. Ford, Alan Valdiviezo, Alina T. Roman-Hubers, Thomas J. McDonald, Weihsueh A. Chiu, Ivan Rusyn
Publikováno v:
Toxics, Vol 11, Iss 1, p 19 (2022)
Cell-based testing of multi-constituent substances and mixtures for their potential adverse health effects is difficult due to their complex composition and physical–chemical characteristics. Various extraction methods are typically used to enable
Externí odkaz:
https://doaj.org/article/fc9176794c6c4349a771bdd356e3d15b
Autor:
Bérénice Charrez, Verena Charwat, Brian A. Siemons, Ishan Goswami, Courtney Sakolish, Yu-Syuan Luo, Henrik Finsberg, Andrew G. Edwards, Evan W. Miller, Ivan Rusyn, Kevin E. Healy
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Despite global efforts, it took 7 months between the proclamation of global SARS-CoV-2 pandemic and the first FDA-approved treatment for COVID-19. During this timeframe, clinicians focused their efforts on repurposing drugs, such as hydroxychloroquin
Externí odkaz:
https://doaj.org/article/24b7f9e303f54de4a211eb7cf95a932a