Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Ivan Rey-Suarez"'
Autor:
Aashli Pathni, Altuğ Özçelikkale, Ivan Rey-Suarez, Lei Li, Scott Davis, Nate Rogers, Zhengguo Xiao, Arpita Upadhyaya
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Cytotoxic T lymphocytes (CTLs) play an integral role in the adaptive immune response by killing infected cells. Antigen presenting cells (APCs), such as dendritic cells, present pathogenic peptides to the T cell receptor on the CTL surface and co-sti
Externí odkaz:
https://doaj.org/article/18c47cf2353d47e8bd6bc3e6214ea529
Autor:
Ivan Rey-Suarez, Brittany A. Wheatley, Peter Koo, Anshuman Bhanja, Zhou Shu, Simon Mochrie, Wenxia Song, Hari Shroff, Arpita Upadhyaya
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
B cell receptors (BCR) capture antigen and initiate downstream antibody responses, but whether and how BCR signaling is regulated by BCR mobility is still unclear. Here the authors show, using single molecule imaging and machine learning analyses, th
Externí odkaz:
https://doaj.org/article/2a250cd833d54780bbb3012f5d131e7e
Autor:
Yicong Wu, Abhishek Kumar, Corey Smith, Evan Ardiel, Panagiotis Chandris, Ryan Christensen, Ivan Rey-Suarez, Min Guo, Harshad D. Vishwasrao, Jiji Chen, Jianyong Tang, Arpita Upadhyaya, Patrick J. La Riviere, Hari Shroff
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Light-sheet fluorescence microscopy enables high resolution imaging of biological samples. Here the authors use reflective coverslips to obtain multiple sample views simultaneously, improving the speed of acquisition and resolution compared to dual-v
Externí odkaz:
https://doaj.org/article/c9d70825284743998dcbe927064d2824
Autor:
Xuesong Li, Yicong Wu, Yijun Su, Ivan Rey-Suarez, Claudia Matthaeus, Taylor B. Updegrove, Zhuang Wei, Lixia Zhang, Hideki Sasaki, Yue Li, Min Guo, John P. Giannini, Harshad D. Vishwasrao, Jiji Chen, Shih-Jong J. Lee, Lin Shao, Huafeng Liu, Kumaran S. Ramamurthi, Justin W. Taraska, Arpita Upadhyaya, Patrick La Riviere, Hari Shroff
Publikováno v:
Nature Biotechnology.
We present two distinct, complementary methods for improving axial resolution in three-dimensional structured illumination microscopy (3D SIM) with minimal or no modification to the optical system. First, we show that placing a mirror directly opposi
Autor:
Yicong Wu, Ryan Christensen, Arpita Upadhyaya, Jiamin Liu, Yilun Sun, Akshay Patel, Titas Sengupta, Yves Pommier, Hari Shroff, Ivan Rey-Suarez, Jonathan S. Daniels, Christian A. Combs, Daniel A. Colón-Ramos, Lingyu Bao, Jiji Chen, Melissa Glidewell, Junhui Sun, Xufeng Wu, Robert S. Fischer, Xiaofei Han, Corey Smith, Leighton H. Duncan, Yun-Bo Shi, Sougata Roy, Yijun Su, Elizabeth Murphy, Patrick J. La Riviere
Publikováno v:
Nature. 600:279-284
Confocal microscopy1 remains a major workhorse in biomedical optical microscopy owing to its reliability and flexibility in imaging various samples, but suffers from substantial point spread function anisotropy, diffraction-limited resolution, depth-
Autor:
Brittany A, Wheatley, Ivan, Rey-Suarez, Matt J, Hourwitz, Sarah, Kerr, Hari, Shroff, John T, Fourkas, Arpita, Upadhyaya
Publikováno v:
Molecular Biology of the Cell. 33
Exposure to MHC-antigen complexes on the surface of antigen-presenting cells (APCs) activates T cells, inducing the formation of the immune synapse (IS). Antigen detection at the APC surface is thus a critical step in the adaptive immune response. Th
Publikováno v:
The FEBS Journal. 289:4430-4446
When B cells are exposed to antigens, they use their B cell receptors (BCRs) to transduce this external signal into internal signaling cascades and uptake antigen, which activate transcriptional programs. Signaling activation requires complex cytoske
Publikováno v:
Molecular Biology of the Cell
Activation of T-cells leads to the formation of immune synapses (ISs) with antigen-presenting cells. This requires T-cell polarization and coordination between the actomyosin and microtubule cytoskeletons. The interactions between these two cytoskele
Autor:
Yue Li, Yijun Su, Min Guo, Xiaofei Han, Jiamin Liu, Harshad D. Vishwasrao, Xuesong Li, Ryan Christensen, Titas Sengupta, Mark W. Moyle, Ivan Rey-Suarez, Jiji Chen, Arpita Upadhyaya, Ted B. Usdin, Daniel Alfonso Colón-Ramos, Huafeng Liu, Yicong Wu, Hari Shroff
Publikováno v:
Nature methods. 19(11)
We present Richardson–Lucy network (RLN), a fast and lightweight deep learning method for three-dimensional fluorescence microscopy deconvolution. RLN combines the traditional Richardson–Lucy iteration with a fully convolutional network structure
Autor:
Arpita Upadhyaya, Hari Shroff, Wenxia Song, Anshuman Bhanja, Zhou Shu, Simon G. J. Mochrie, Ivan Rey-Suarez, Brittany A. Wheatley, Peter K. Koo
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Nature Communications
Regulation of membrane receptor mobility tunes cellular response to external signals, such as in binding of B cell receptors (BCR) to antigen, which initiates signaling. However, whether BCR signaling is regulated by BCR mobility, and what factors me