Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ivan Ramirez Moral"'
Autor:
Alex R Schuurman, Tom DY Reijnders, Anno Saris, Ivan Ramirez Moral, Michiel Schinkel, Justin de Brabander, Christine van Linge, Louis Vermeulen, Brendon P Scicluna, W Joost Wiersinga, Felipe A Vieira Braga, Tom van der Poll
Publikováno v:
eLife, Vol 10 (2021)
The exact immunopathophysiology of community-acquired pneumonia (CAP) caused by SARS-CoV-2 (COVID-19) remains clouded by a general lack of relevant disease controls. The scarcity of single-cell investigations in the broader population of patients wit
Externí odkaz:
https://doaj.org/article/86b1440bbe734205ab4a4e76ebe22bbb
Autor:
Jack Yang, Ivan Ramirez Moral, Cornelis van ’t Veer, Alex F. de Vos, Regina de Beer, Joris J. T. H. Roelofs, B. Paul Morgan, Tom van der Poll
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-10 (2019)
Abstract Background Complement factor C5 can either aggravate or attenuate the T-helper type 2 (TH2) immune response and airway hyperresponsiveness (AHR) in murine models of allergic asthma. The effect of C5 during the effector phase of allergen-indu
Externí odkaz:
https://doaj.org/article/b815ce62772b490aa5436b9ceeb4cba6
Autor:
Ivan Ramirez-Moral, Alex R. Schuurman, Christine C.A. van Linge, Joe M. Butler, Xiao Yu, Karen de Haan, Sarah van Leeuwen, Alex F. de Vos, Menno D. de Jong, Felipe A. Vieira Braga, Tom van der Poll
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110662- (2024)
Summary: Airway epithelial cells represent the first line of defense against respiratory pathogens. Flagellin drives the motility of many mucosal pathogens and has been suggested as an immune enhancing adjunctive therapeutic in infections of the airw
Externí odkaz:
https://doaj.org/article/819ebe64dbea43b881ff22d0a2d42a13
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-4 (2021)
Abstract Agonists of peroxisome proliferator-activated receptor (PPAR)-γ have been suggested as potential adjuvant therapy in bacterial pneumonia because of their capacity to inhibit inflammation and enhance bacterial clearance. Previous studies onl
Externí odkaz:
https://doaj.org/article/b697a7efe2fb46b8bacff604b72b004f
Autor:
Bianca L Ferreira, Ivan Ramirez-Moral, Natasja A Otto, Reinaldo Salomão, Alex F de Vos, Tom van der Poll
Publikováno v:
Clinical and experimental immunology, 207(3), 370-377. Wiley-Blackwell
Clin Exp Immunol
Clin Exp Immunol
Pseudomonas aeruginosa is a common respiratory pathogen that causes injurious airway inflammation during acute pneumonia. Peroxisome proliferator-activated receptor (PPAR)-γ is involved in the regulation of metabolic and inflammatory responses in di
Autor:
Ivan Ramirez-Moral, Alex R. Schuurman, Joe M. Butler, Xiao Yu, Karen de Haan, Sarah van Leeuwen, Alex F. de Vos, Menno D. de Jong, Felipe A. Vieira Braga, Tom van der Poll
Respiratory epithelial cells line the airways and represent the first line of defense against respiratory pathogens. The cellular heterogeneity of the airway wall has only recently been recognized by single-cell analyses. Here, we leveraged single-ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e330a9aa2bb3e13286f1d8914caa4725
https://doi.org/10.1101/2022.11.02.514918
https://doi.org/10.1101/2022.11.02.514918
Publikováno v:
Respiratory research, 22(1):230. BioMed Central
Respiratory Research
Respiratory Research, Vol 22, Iss 1, Pp 1-4 (2021)
Respiratory Research
Respiratory Research, Vol 22, Iss 1, Pp 1-4 (2021)
Agonists of peroxisome proliferator-activated receptor (PPAR)-γ have been suggested as potential adjuvant therapy in bacterial pneumonia because of their capacity to inhibit inflammation and enhance bacterial clearance. Previous studies only assesse
Autor:
Christine van Linge, Anno Saris, Felipe A. Vieira Braga, Michiel Schinkel, Louis Vermeulen, Tom van der Poll, Tom D Y Reijnders, Ivan Ramirez Moral, Justin de Brabander, W. Joost Wiersinga, Alex R. Schuurman, Brendon P. Scicluna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7e48c07909d0bda40a9aa9cb987e5d7
https://doi.org/10.7554/elife.69661.sa2
https://doi.org/10.7554/elife.69661.sa2
Autor:
Anno Saris, Brendon P. Scicluna, Felipe A. Vieira Braga, Louis Vermeulen, Justin de Brabander, Christine van Linge, W. Joost Wiersinga, Ivan Ramirez Moral, Tom van der Poll, Tom D Y Reijnders, Michiel Schinkel, Alex R. Schuurman
Publikováno v:
Schuurman, A R, Reijnders, T D Y, Saris, A, Moral, I R, Schinkel, M, de Brabander, J, van Linge, C, Vermeulen, L, Scicluna, B P, Wiersinga, W J, Braga, F A V & van der Poll, T 2021, ' Integrated single-cell analysis unveils diverging immune features of covid-19, influenza, and other community-acquired pneumonia ', eLife, vol. 10, e69661 . https://doi.org/10.7554/eLife.69661
eLife
eLife, 10:e69661. eLife Sciences Publications Limited
eLife, 10:e69661. eLife Sciences Publications
eLife, Vol 10 (2021)
eLife
eLife, 10:e69661. eLife Sciences Publications Limited
eLife, 10:e69661. eLife Sciences Publications
eLife, Vol 10 (2021)
The exact immunopathophysiology of community-acquired pneumonia (CAP) caused by SARS-CoV-2 (COVID-19) remains clouded by a general lack of relevant disease controls. The scarcity of single-cell investigations in the broader population of patients wit
Autor:
Liza Pereverzeva, Christine C.A. van Linge, Alex R. Schuurman, Augustijn M. Klarenbeek, Ivan Ramirez Moral, Natasja A. Otto, Hessel Peters-Sengers, Joe M. Butler, Bauke V. Schomakers, Michel van Weeghel, Riekelt H. Houtkooper, W. Joost Wiersinga, Peter I. Bonta, Jouke T. Annema, Alex F. de Vos, Tom van der Poll
Publikováno v:
Biochimica et Biophysica Acta-Molecular Basis of Disease, 1868(10):166488. Elsevier
Pereverzeva, L, van Linge, C C A, Schuurman, A R, Klarenbeek, A M, Ramirez Moral, I, Otto, N A, Peters-Sengers, H, Butler, J M, Schomakers, B V, van Weeghel, M, Houtkooper, R H, Wiersinga, W J, Bonta, P I, Annema, J T, de Vos, A F & van der Poll, T 2022, ' Human alveolar macrophages do not rely on glucose metabolism upon activation by lipopolysaccharide ', Biochimica et Biophysica Acta-Molecular Basis of Disease, vol. 1868, no. 10, 166488 . https://doi.org/10.1016/j.bbadis.2022.166488
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 1868(10):166488. Elsevier
Pereverzeva, L, van Linge, C C A, Schuurman, A R, Klarenbeek, A M, Ramirez Moral, I, Otto, N A, Peters-Sengers, H, Butler, J M, Schomakers, B V, van Weeghel, M, Houtkooper, R H, Wiersinga, W J, Bonta, P I, Annema, J T, de Vos, A F & van der Poll, T 2022, ' Human alveolar macrophages do not rely on glucose metabolism upon activation by lipopolysaccharide ', Biochimica et Biophysica Acta-Molecular Basis of Disease, vol. 1868, no. 10, 166488 . https://doi.org/10.1016/j.bbadis.2022.166488
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 1868(10):166488. Elsevier
Most macrophages generate energy to mount an inflammatory cytokine response by increased glucose metabolism through intracellular glycolysis. Previous studies have suggested that alveolar macrophages (AMs), which reside in a glucose-poor natural envi