Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Ivan Psakhye"'
Publikováno v:
Genes & Development. 35:1368-1382
The alternative PCNA loader containing CTF18-DCC1-CTF8 facilitates sister chromatid cohesion (SCC) by poorly defined mechanisms. Here we found that in DT40 cells, CTF18 acts complementarily with the Warsaw breakage syndrome DDX11 helicase in mediatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8cc43fc0bb8a4df7afadff058f4c11f
https://doi.org/10.1101/gad.348581.121
https://doi.org/10.1101/gad.348581.121
Sister chromatid cohesion is essential for faithful chromosome segregation and genome duplication during cell division. Failure to establish cohesion during S phase by the ring-shaped multiprotein complex cohesin leads to genomic instability1-4. Repl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2b49d4961fc74d82716482cccb5dc1a
https://doi.org/10.1101/2022.09.16.508217
https://doi.org/10.1101/2022.09.16.508217
Autor:
Dana Branzei, Ivan Psakhye
Structural maintenance of chromosomes (SMC) complexes, cohesin, condensin and Smc5/6, are essential for viability and participate in multiple processes, including sister chromatid cohesion, chromosome condensation, and DNA repair. Here we show that S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c145948a8f7363bb221c534887a120f
https://doi.org/10.1101/2020.11.13.381483
https://doi.org/10.1101/2020.11.13.381483
Autor:
Ivan Psakhye, Dana Branzei
Publikováno v:
Current Opinion in Cell Biology. 40:137-144
Accurate chromosomal DNA replication is fundamental for optimal cellular function and genome integrity. Replication perturbations activate DNA damage tolerance pathways, which are crucial to complete genome duplication as well as to prevent formation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc8df5d52d1fccacda540e7dfc749e1d
https://doi.org/10.1016/j.ceb.2016.03.015
https://doi.org/10.1016/j.ceb.2016.03.015
Publikováno v:
The Journal of Biological Chemistry
Journal of Biological Chemistry
Journal of Biological Chemistry
Modification by the ubiquitin-like protein SUMO affects hundreds of cellular substrate proteins and regulates a wide variety of physiological processes. While the SUMO system appears to predominantly target nuclear proteins and, to a lesser extent, c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::265b15a85d568837beed22030409fda0
https://pubmed.ncbi.nlm.nih.gov/29183993
https://pubmed.ncbi.nlm.nih.gov/29183993
Publikováno v:
Cell. 158(3):549-563
Summary Selective ubiquitin-dependent autophagy plays a pivotal role in the elimination of protein aggregates, assemblies, or organelles and counteracts the cytotoxicity of proteins linked to neurodegenerative diseases. Following substrate ubiquityla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bf0588095f24248c3b2a9cd0a876180
Publikováno v:
Molecular Cell
Summary Similar to ubiquitin, SUMO forms chains, but the identity of SUMO-chain-modified factors and the purpose of this modification remain largely unknown. Here, we identify the budding yeast SUMO protease Ulp2, able to disassemble SUMO chains, as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4710c5e4bad4634dcb2d04efa69a43d6
http://europepmc.org/articles/PMC6891891
http://europepmc.org/articles/PMC6891891
Autor:
Stefan Jentsch, Ivan Psakhye
Publikováno v:
Annual Review of Genetics. 47:167-186
Reversible modification of proteins by SUMO (small ubiquitin-like modifier) affects a large number of cellular processes. In striking contrast to the related ubiquitin pathway, only a few enzymes participate in the SUMO system, although this pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efcafa52208fd8fbaa08e4249c1d288c
https://doi.org/10.1146/annurev-genet-111212-133453
https://doi.org/10.1146/annurev-genet-111212-133453
Autor:
Ivan, Psakhye, Stefan, Jentsch
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1475
Protein modification by conjugation to the ubiquitin-related protein SUMO (SUMOylation) regulates numerous cellular functions and is reversible. However, unlike typical posttranslational modifications, SUMOylation often targets and regulates proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e63e4542a656903f2de92850234c5e41
https://pubmed.ncbi.nlm.nih.gov/27631809
https://pubmed.ncbi.nlm.nih.gov/27631809
Autor:
Stefan Jentsch, Ivan Psakhye
Publikováno v:
Methods in Molecular Biology ISBN: 9781493963560
Protein modification by conjugation to the ubiquitin-related protein SUMO (SUMOylation) regulates numerous cellular functions and is reversible. However, unlike typical posttranslational modifications, SUMOylation often targets and regulates proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9c58721053be3f7fcde5d30746abe5e
https://doi.org/10.1007/978-1-4939-6358-4_16
https://doi.org/10.1007/978-1-4939-6358-4_16