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Akademický článek

Hematopoietic Cell Transplantation Trends and Outcomes in Canada: A Registry-Based Cohort Study

Autor: Matthew D. Seftel, Ivan Pasic, Gaganvir Parmar, Oliver Bucher, David S. Allan, Sita Bhella, Kevin Anthony Hay, Oluwaseun Ikuomola, Grace Musto, Anca Prica, Erin Richardson, Tony H. Truong, Kristjan Paulson

Publikováno v: Current Oncology, Vol 30, Iss 11, Pp 9953-9967 (2023)

Background: Hematopoietic cell transplantation (HCT) is an established therapy for hematologic malignancies and serious non-malignant blood disorders. Despite its curative potential, HCT is associated with substantial toxicity and health resource uti

Externí odkaz: https://doaj.org/article/68837b5ed0774b23892c3c247e8b55e7

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Akademický článek

The 17‐gene stemness score associates with relapse risk and long‐term outcomes following allogeneic haematopoietic cell transplantation in acute myeloid leukaemia

Publikováno v: eJHaem, Vol 3, Iss 3, Pp 873-884 (2022)

Abstract A 17‐gene stemness (LSC17) score determines risk in acute myeloid leukaemia patients treated with standard chemotherapy regimens. The present study further analysed the impact of the LSC17 score at diagnosis on outcomes following allogenei

Externí odkaz: https://doaj.org/article/369a826fb44c40558e7eed079916d481

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Akademický článek

Clonal hematopoiesis in the donor does not adversely affect long-term outcomes following allogeneic hematopoietic stem cell transplantation: result from a 13-year follow-up

Publikováno v: Haematologica, Vol 108, Iss 7 (2023)

Donor clonal hematopoiesis may be transferred to the recipient through allogeneic hematopoietic stem cell transplantation (HSCT), but the potential for adverse long-term impact on transplant outcomes remains unknown. A total of 744 samples from 372 r

Externí odkaz: https://doaj.org/article/63eae2c453294c49965bc79b50918746

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Multiplex proteomics using proximity extension assay for the identification of protein biomarkers predictive of acute graft-vs.-host disease in allogeneic hematopoietic cell transplantation

Autor: Ivan Pasic, Annie H. Ren, Ram Vasudevan Nampoothiri, Ioannis Prassas, Jeffrey H. Lipton, Jonas Mattsson, Eleftherios P. Diamandis, Fotios V. Michelis

Publikováno v: Clinical Chemistry and Laboratory Medicine (CCLM). 61:1005-1014

Objectives Allogeneic hematopoietic cell transplantation (HCT) is associated with acute graft-vs.-host disease (aGVHD). The presented study applied a novel multiplex antibody-based proximity extension assay (PEA) proteomic platform that can detect th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::29f7752aee94ca5448121cb18145f237
https://doi.org/10.1515/cclm-2022-0916

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Acute kidney injury within 100 days post allogeneic hematopoietic cell transplantation is associated with increased risk of post-transplant complications and poor transplant outcomes

Autor: Kayla Madsen, Karyne Pelletier, Gabrielle Côté, Abhijat Kitchlu, Shiyi Chen, Jonas Mattsson, Ivan Pasic

Publikováno v: Bone Marrow Transplantation. 57:1411-1420

Allogeneic hematopoietic cell transplantation (HCT) offers cure for some patients with hematological diseases but is associated with significant risk of morbidity and mortality. We investigated the incidence of AKI and its impact on transplant outcom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b47cae9a8cff9553c4be162ae40e1b5c
https://doi.org/10.1038/s41409-022-01744-0

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