Human resistin is a systemic immune-derived proinflammatory cytokine targeting both leukocytes and adipocytes.

Autor: Ivan Nagaev, Maria Bokarewa, Andrej Tarkowski, Ulf Smith

Publikováno v: PLoS ONE, Vol 1, p e31 (2006)

The characteristics of human resistin (RETN) are unclear and controversial despite intensive adipose-focused research. Its transcriptional and functional similarity with the murine myeloid-specific and CCAAT/enhancer binding protein epsilon (Cebpe)-d

Externí odkaz: https://doaj.org/article/754e14a7bf604e98bf69a3cf4a523e4a

Enhanced local and systemic inflammatory cytokine mRNA expression in women with endometriosis evokes compensatory adaptive regulatory mRNA response that mediates immune suppression and impairs cytotoxicity

Autor: Emma Björk, Olga Nagaeva, Eva Lundin, Ulrika Ottander, Ivan Nagaev, Marie-Therese Vinnars, Lucia Mincheva-Nilsson

Publikováno v: American Journal of Reproductive Immunology. 84

Problem Endometriosis is a disease characterized by ectopic implantation of endometrium and impaired immune responses. To explore its pathogenic mechanisms, we studied the local and systemic cytokine mRNA profiles and their role in the immunity of pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da1f5a004f6ab8fd3ce73160d01dc893
https://doi.org/10.1111/aji.13298

Cytokine mRNA and protein expression by cell cultures of epithelial ovarian cancer-Methodological considerations on the choice of analytical method for cytokine analyses

Autor: Lucia Mincheva-Nilsson, Pernilla Israelsson, Eva Lundin, Ivan Nagaev, Eva Dehlin, Ulrika Ottander

Publikováno v: American journal of reproductive immunology (New York, N.Y. : 1989)REFERENCES. 84(1)

Problem: To get a comprehensive picture of cytokine expression in health and disease is difficult, cytokines are transiently and locally expressed, and protein analyses are burdened by biological modifications, technical issues, and sensitivity to ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::390105b7aff6572819c19882025c0c5c
https://pubmed.ncbi.nlm.nih.gov/32307767

Melanocortin 2, 3 and 4 receptor gene expressions are downregulated in CD8+ T cytotoxic lymphocytes and CD19+ B lymphocytes in rheumatoid arthritis responding to TNFα inhibition

Autor: Jarl E. S. Wikberg, Grethe Neumann Andersen, Olga Nagaeva, Ivan Nagaev, Michael Kruse Meyer, Lucia Mincheva-Nilsson, Marlene Andersen

Publikováno v: Andersen, M, Nagaev, I, Meyer, M K, Nagaeva, O, Wikberg, J E S, Mincheva-Nilsson, L & Andersen, G N 2017, ' Melanocortin 2, 3 and 4 receptor gene expressions are downregulated in CD8+ T cytotoxic lymphocytes and CD19+ B lymphocytes in rheumatoid arthritis responding to TNFα inhibition ', Scandinavian Journal of Immunology, vol. 86, no. 1, pp. 31-39 . https://doi.org/10.1111/sji.12555

Melanocortin signalling in leucocyte subsets elicits anti-inflammatory and immune tolerance inducing effects in animal experimental inflammation. In man, however, the effects of melanocortin signal ...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::178d79e7906fd5f02c76f458248b32af
https://vbn.aau.dk/da/publications/6bfaee22-dd1b-4bdc-a512-8a181c90c776

Enhanced Th1 and inflammatory mRNA responses upregulate NK cell cytotoxicity and NKG2D ligand expression in human pre-eclamptic placenta and target it for NK cell attack

Autor: Ulrika Ottander, Marie-Therese Vinnars, Emma Björk, Katarina Bremme, Eva Sverremark-Ekström, Ulrika Holmlund, Lucia Mincheva-Nilsson, Ivan Nagaev

Publikováno v: American Journal of Reproductive Immunology. 80:e12969

Pre-eclampsia (PE), a severe human pregnancy disorder, is associated with exaggerated systemic inflammation, enhanced cytokine production, and increased shedding of microvesicles leading to endothelial dysfunction, coagulopathy, and extensive placent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b810eecf3ac224903cf8fc5c0f73a22e
https://doi.org/10.1111/aji.12969