Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Ivan M. L. Chua"'
Autor:
Rahul Nahar, Weiwei Zhai, Tong Zhang, Angela Takano, Alexis J. Khng, Yin Yeng Lee, Xingliang Liu, Chong Hee Lim, Tina P. T. Koh, Zaw Win Aung, Tony Kiat Hon Lim, Lavanya Veeravalli, Ju Yuan, Audrey S. M. Teo, Cheryl X. Chan, Huay Mei Poh, Ivan M. L. Chua, Audrey Ann Liew, Dawn Ping Xi Lau, Xue Lin Kwang, Chee Keong Toh, Wan-Teck Lim, Bing Lim, Wai Leong Tam, Eng-Huat Tan, Axel M. Hillmer, Daniel S. W. Tan
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
EGFR mutant lung adenocarcinoma (LUAD) exhibit diverse clinical outcomes in response to targeted therapies. Here the authors show that these LUADs involve a complex genomic landscape with high intratumor heterogeneity, providing insights into the evo
Externí odkaz:
https://doaj.org/article/358b10958e814ff3ae9b2917b6e35d5b
Autor:
Axel M. Hillmer, Lavanya Veeravalli, Bing Lim, Tong Zhang, Chong Hee Lim, Huay Mei Poh, Rahul Nahar, Tony Kiat Hon Lim, Alexis Jiaying Khng, Yin Yeng Lee, Ju Yuan, Xue Lin Kwang, Daniel Shao-Weng Tan, Wai Leong Tam, Xingliang Liu, Wan-Teck Lim, Dawn Pingxi Lau, Audrey S.M. Teo, Eng Huat Tan, Tina P.T. Koh, Audrey Ann Liew, Zaw Win Aung, Weiwei Zhai, Cheryl Xueli Chan, Chee Keong Toh, Angela Takano, Ivan M. L. Chua
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications
Nature Communications
EGFR-mutant lung adenocarcinomas (LUAD) display diverse clinical trajectories and are characterized by rapid but short-lived responses to EGFR tyrosine kinase inhibitors (TKIs). Through sequencing of 79 spatially distinct regions from 16 early stage