Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Ivan Ischenko"'
Autor:
Hanno Nieß, Joachim W. Ellwart, Josef Mysliwietz, Karl-Walter Jauch, Ivan Ischenko, L. Zhao, B. Schwarz, Peter J. Nelson, Peter Camaj, Qi Bao, Yan Wang, Yue Zhao, Andrea Renner, Christiane Bruns
Publikováno v:
Targeted Oncology. 10:535-548
Our preliminary studies identified a small population side population (SP) cells in pancreatic cancer cells with stem cell-like properties, which were able to induce fast and aggressive tumor formation in nude mice. Gene expression analysis showed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f40286b03885c5635aa3ebebf052c1aa
https://doi.org/10.1007/s11523-015-0360-2
https://doi.org/10.1007/s11523-015-0360-2
Autor:
Karl-Walter Jauch, Stefan Boeck, Hendrik Seeliger, Christiane J. Bruns, Martin K. Angele, Martin E. Eichhorn, Volker Heinemann, Simone Christians, Axel Kleespies, Ivan Ischenko
Publikováno v:
The American Journal of Surgery. 200:311-317
Background Pancreatic fistula (PF) represents a major complication after distal pancreatectomy. In a consecutive series of 110 patients, risk factors for the incidence of PF and surgical morbidity were identified. Methods Patients having undergone di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a20e36981c24507c4cd4e225a92f53b
https://doi.org/10.1016/j.amjsurg.2009.10.022
https://doi.org/10.1016/j.amjsurg.2009.10.022
Autor:
Karl-Walter Jauch, Peter Camaj, H. Seeliger, M. Eichhorn, C.J. Bruns, A. Kleespies, Ivan Ischenko, M. Guba
Publikováno v:
Current Cancer Drug Targets. 10:546-553
Purpose: The close association of lymphatic and blood vessels and their coordinated development in vivo suggest that there are parallel mechanisms regulating hemangiogenesis and lymphangiogenesis. Here, we hypothesize that inhibition of the Src tyros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84cab785238bb31c357292d0474bbada
https://doi.org/10.2174/156800910791517181
https://doi.org/10.2174/156800910791517181
Autor:
Ivan Ischenko, Christiane J. Bruns, Uta M. Schneiders, Stefan Zahler, Angelika M. Vollmar, Romina M. Wiedmann, Andrea S. Rothmeier, Anita Rudy
Publikováno v:
International Journal of Cancer. 127:1096-1105
Treatment of pancreatic cancer remains a major challenge and new anticancer drugs are urgently required. Our study presents the marine natural compound spongistatin 1 as a promising experimental drug. Spongistatin 1 was applied in an orthotopic in vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::effdc19b108a278b7a2a7a5e1dfbf0b7
https://doi.org/10.1002/ijc.25241
https://doi.org/10.1002/ijc.25241
Autor:
Helmut Blum, Ivan Ischenko, Peter Camaj, Dagmar Faktorova, Enrico N. De Toni, Hendrik Seeliger, Karl-Walter Jauch, Christiane Bruns, Stefan Krebs
Publikováno v:
bchm. 390:1293-1302
The EGF-related protein EFEMP1 (EGF-containing fibulin-like extracellular matrix protein 1) has been shown to promote tumor growth in human adenocarcinoma. To understand the mechanism of this action, the signal transduction activated upon treatment w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d73a5b0dedb209d1b753aee18b055f1b
https://doi.org/10.1515/bc.2009.140
https://doi.org/10.1515/bc.2009.140
Autor:
Karl-Walter Jauch, A. Werner, Christiane J. Bruns, Siiri Luedemann, Uwe Michaelis, Gerhard Preissler, Ivan Ischenko, A. Papyan, Martin E. Eichhorn, Sebastian Strieth, Eric Guenzi, Marc Dellian, Hermann Bohnenkamp
Publikováno v:
International Journal of Cancer. 126:1235-1245
Cationic lipid complexed paclitaxel (EndoTAG-1) is a novel vascular targeting agent for the treatment of cancer. Here, the aim was to investigate intratumoral drug distribution after EndoTAG-1 therapy and analyze the impact of EndoTAG-1 scheduling on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f5899d695eced6c40016d8b9538b984
https://doi.org/10.1002/ijc.24846
https://doi.org/10.1002/ijc.24846
Autor:
Christiane J. Bruns, Karl-Walter Jauch, Martin K. Angele, Ivan Ischenko, Martin E. Eichhorn, Axel Kleespies, Hendrik Seeliger
Publikováno v:
Langenbeck's Archives of Surgery. 395:1-10
Since the discovery of cancer cells with stem-like characteristics in hematopoietic malignancies and, more recently, in solid tumors, enormous attention has been paid to the stem-cell nature of pancreatic cancer. Among the most important properties o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6b079c69424bcb480813a71a24fb620
https://doi.org/10.1007/s00423-009-0502-z
https://doi.org/10.1007/s00423-009-0502-z
Autor:
Helmut Blum, Karl-Walter Jauch, Axel Kleespies, Enrico N. De Toni, Christiane Bruns, Peter Camaj, Ivan Ischenko, Gerald Assmann, Susanne E. Thieme, Hendrik Seeliger
Publikováno v:
Molecular Cancer Research. 7:189-198
The progression of pancreatic cancer is dependent on local tumor growth, angiogenesis, and metastasis. EFEMP1, a recently discovered member of the fibulin family, was characterized with regard to these key elements of pancreatic cancer progression. D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a35e1a8415d1afa5f2b32f52a87dcc1
https://doi.org/10.1158/1541-7786.mcr-08-0132
https://doi.org/10.1158/1541-7786.mcr-08-0132
Autor:
Ivan Ischenko, Dorota Garczarczyk, Angelika M. Vollmar, Stefan Zahler, Jos Joore, Christiane J. Bruns, Andrea S. Rothmeier, Robert Fürst
Publikováno v:
The FASEB Journal. 23:1127-1137
The aims of the study were to meet the demand of new tubulin antagonists with fewer side effects by characterizing the antiangiogenic properties of the experimental compound spongistatin 1, and to elucidate nonmitotic mechanisms by which tubulin anta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37a27ee80220d6eb2e4db695f1c286ff
https://doi.org/10.1096/fj.08-117127
https://doi.org/10.1096/fj.08-117127
Publikováno v:
Current Medicinal Chemistry. 15:3171-3184
One of the most exciting concepts being explored in cancer research today is the idea of cancer stem cells. Evidence for the existence of such cells was first proposed for haematological malignancies and, more recently, for solid tumors, including br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f94f6bd77465326a47513481938e446
https://doi.org/10.2174/092986708786848541
https://doi.org/10.2174/092986708786848541