Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Ivan Hilgert"'
Autor:
Jan Konvalinka, Cyril Barinka, Pavel Šácha, Josef Zamecnik, Tomas Eckschlager, Ivan Hilgert, Klára Hlouchová, Petra Mlčochová, Ales Vicha
Publikováno v:
Neuroscience. 144:1361-1372
Glutamate carboxypeptidase II (GCPII) is a transmembrane glycoprotein expressed in various tissues. When expressed in the brain it cleaves the neurotransmitter N-acetylaspartylglutamate (NAAG), yielding free glutamate. In jejunum it hydrolyzes folylp
Publikováno v:
Cellular Immunology. 236:42-47
Non-lineage section studied in total 90 mAb samples, including 23 submitted as known CD specificities. Thirty four samples submitted as unknown and potentially novel specificities recognized actually well known molecules (HLA class I, CD7, 11b, 14, 1
Autor:
Pavel Majer, Václav Hořejší, Jan Konvalinka, Pavel Šácha, Barbara S. Slusher, Cyril Bařinka, Ivan Hilgert, Petra Mlčochová
Publikováno v:
European Journal of Biochemistry. 271:2782-2790
Human glutamate carboxypeptidase II (GCPII) is a co-catalytic metallopeptidase and its putative catalytic domain is homologous to the aminopeptidases from Vibrio proteolyticus and Streptomyces griseus. In humans, the enzyme is expressed predominantly
Autor:
Jack L. Strominger, Lawrence J. Stern, Sriram Chitta, Michelle A. J. Palmer, Rick Baggio, Vaclav Horejsi, Ivan Hilgert, Jaime E. Arenas, Laura Santambrogio, Mia M. Rushe, Gregory J. Carven
Publikováno v:
Journal of Biological Chemistry. 279:16561-16570
Class II major histocompatibility complex (MHC) proteins bind peptides and present them at the cell surface for interaction with CD4+ T cells as part of the system by which the immune system surveys the body for signs of infection. Peptide binding is
Autor:
Tomas Brdicka, Naděžda Brdičková, Luca Simeoni, Vaclav Horejsi, Jiri Spicka, Burkhart Schraven, Stefanie Kliche, Ondrej Horvath, Camilla Merten, Ivan Hilgert, Jan Pačes, Pavla Angelisova
Publikováno v:
The Journal of Experimental Medicine
Lymphocyte membrane rafts contain molecules critical for immunoreceptor signaling. Here, we report identification of a new raft-associated adaptor protein LIME (Lck-interacting molecule) expressed predominantly in T lymphocytes. LIME becomes tyrosine
Autor:
Tomas Brdicka, Petra Lusková, Marie Malissen, Jürgen Wienands, Luca Simeoni, Enrique Aguado, Ivan Hilgert, Jiri Spicka, Ondrej Horvath, Petr Novák, Naděžda Brdičková, Vaclav Horejsi, Petr Dráber, Burkhart Schraven, Pavla Angelisova, Martin Imrich, Niklas Engels, Jan Österreicher
Publikováno v:
Journal of Experimental Medicine. 196:1617-1626
A key molecule necessary for activation of T lymphocytes through their antigen-specific T cell receptor (TCR) is the transmembrane adaptor protein LAT (linker for activation of T cells). Upon TCR engagement, LAT becomes rapidly tyrosine phosphorylate
Autor:
Anne Marie-Cardine, Aliz Barakonyi, Julie Tabiasco, Philippe Le Bouteiller, Jérôme Giustiniani, Françoise Lenfant, Ivan Hilgert, Armand Bensussan, Magali Rabot, Fathia Mami-Chouaib, Laurence Boumsell, Maryse Aguerre-Girr
Publikováno v:
Proceedings of the National Academy of Sciences. 99:16963-16968
Circulating human natural killer (NK) lymphocytes have been functionally defined by their ability to exert cytotoxic activity against MHC class I-negative target cell lines, including K562. Therefore, it was proposed that NK cells recognized the “m
Autor:
Elisabeth H. Weiss, Gabriele Hahn, Christine S. Falk, Ivan Hilgert, Michael Mach, Dolores J. Schendel
Publikováno v:
The Journal of Immunology. 169:3257-3266
A highly attractive approach to investigate the influence and hierarchical organization of viral proteins on cellular immune responses is to employ mutant viruses carrying deletions of various virus-encoded, immune-modulating genes. Here, we introduc