Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Ivan Goussakov"'
Autor:
Alexander Drobyshevsky, Sylvia Synowiec, Ivan Goussakov, Rafael Fabres, Jing Lu, Michael Caplan
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
ABSTRACTPremature infants lack a normal intestinal microbial community and also at risk of perinatal hypoxic-ischemic (HI) brain injury, which is considered to be one of the major factors for motor, sensory, and cognitive deficits. We hypothesized th
Externí odkaz:
https://doaj.org/article/e4bab0b3caaa4eb9a85486405df2a102
Autor:
Alexander Drobyshevsky, Sylvia Synowiec, Ivan Goussakov, Jing Lu, David Gascoigne, Daniil P Aksenov, Vasily Yarnykh
Publikováno v:
NeuroImage, Vol 270, Iss , Pp 119974- (2023)
Introduction: Quantitative and non-invasive measures of brain myelination and maturation during development are of great importance to both clinical and translational research communities. While the metrics derived from diffusion tensor imaging, are
Externí odkaz:
https://doaj.org/article/d3903d5347694d14af460164bc8fc52f
Publikováno v:
Frontiers in Neurology, Vol 9 (2019)
Rabbit kits after global antenatal hypoxic-ischemic injury exhibit motor deficits similar to humans with cerebral palsy. We tested several mechanisms previously implicated in spinal hyper-excitability after perinatal brain injury that may explain mus
Externí odkaz:
https://doaj.org/article/689d5ad652eb43b8b8288f6672074adf
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e40898 (2012)
We previously showed that the time-dependent intensification ("incubation") of cue-induced cocaine seeking after withdrawal from extended-access cocaine self-administration is accompanied by accumulation of Ca(2+)-permeable AMPA receptors (CP-AMPARs)
Externí odkaz:
https://doaj.org/article/aaef048474de4b9996ee464183209aa3
Autor:
Shreaya Chakroborty, Clark Briggs, Megan B Miller, Ivan Goussakov, Corinne Schneider, Joyce Kim, Jaime Wicks, Jill C Richardson, Vincent Conklin, Benjamin G Cameransi, Grace E Stutzmann
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52056 (2012)
Alzheimer's disease (AD) is a devastating neurodegenerative condition with no known cure. While current therapies target late-stage amyloid formation and cholinergic tone, to date, these strategies have proven ineffective at preventing disease progre
Externí odkaz:
https://doaj.org/article/783aa06eb23944a3a2a2e68aa3c56255
Publikováno v:
Int J Dev Neurosci
Apnea of prematurity is a common clinical condition that occurs in premature infants and results in intermittent hypoxia (IH) to brain and other organs. While short episodes of apnea are considered of no clinical significance, prolonged apnea with br
Publikováno v:
Frontiers in Neurology, Vol 9 (2019)
Frontiers in Neurology
Frontiers in Neurology
Rabbit kits after global antenatal hypoxic-ischemic injury exhibit motor deficits similar to humans with cerebral palsy. We tested several mechanisms previously implicated in spinal hyper-excitability after perinatal brain injury that may explain mus
Publikováno v:
Exp Neurol
To elucidate the mechanisms of memory impairment after chronic neonatal intermittent hypoxia (IH), we employed a mice model of severe IH administered at postnatal days 3 to 7. Since prior studies in this model did not demonstrate increased cell death
Publikováno v:
Channels. 5:9-13
Ryanodine receptor (RyR)-mediated Ca(2+) dysregulation is associated with Alzheimer's disease (AD) neuropathology. Using 2-photon Ca(2+) imaging and patch clamp recordings in brain slice preparations from young 3xTg-AD and NonTg control mice, we rece
Publikováno v:
The Journal of Neuroscience. 30:12128-12137
Deficits in synaptic function, particularly through NMDA receptors (NMDARs), are linked to late-stage cognitive impairments in Alzheimer's disease (AD). At earlier disease stages, however, there is evidence for altered endoplasmic reticulum (ER) calc