Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ivan G. Logvinenko"'
Publikováno v:
Журнал органічної та фармацевтичної хімії, Vol 19, Iss 1, Pp 3-9 (2021)
Aim. To develop a convenient synthetic approach for the preparation of multigram amounts of 4-(trifluoromethoxy)-piperidine and 4-(trifluoromethoxymethyl)piperidine – promising building blocks for medicinal chemistry. Results and discussion. 4-(
Externí odkaz:
https://doaj.org/article/b53720b462db4c03b6498ead4e11fa30
Autor:
Ivan G. Logvinenko, Ivan S. Kondratov, Stanislav O. Pridma, Nataliya A. Tolmachova, Roman N. Morev, Violetta G. Dolovanyuk, Andrii L. Boretskyi, Roman O. Stepaniuk, Serhii A. Trofymchuk, Christian Mück-Lichtenfeld, Constantin G. Daniliuc, Günter Haufe
Publikováno v:
Journal of Fluorine Chemistry. :109990
Autor:
Günter Haufe, Constantin G. Daniliuc, Nataliya A. Tolmachova, Florian Clausen, Ivan G. Logvinenko, Maria Kliachyna, Roman N. Morev, Ivan S. Kondratov
Publikováno v:
Organic & Biomolecular Chemistry. 15:672-679
2-Amino-2-(trifluoromethoxy)butanoic acid (O-trifluoromethyl homoserine) was synthesized as a racemate and in both enantiomeric forms. The measured pKa and log D values establish the compound as a promising analogue of natural aliphatic amino acids.
Autor:
Alexey V. Dobrydnev, Oleksandr O. Grygorenko, Andriy V. Kozytskiy, Ivan G. Logvinenko, Ivan S. Kondratov
Publikováno v:
Journal of Fluorine Chemistry. 246:109799
A two-step approach to the synthesis of ω-CF3O-substituted aliphatic sulfonyl chlorides is reported. The method is based on the reaction of alkylating agents bearing a ω-CF3O substituent with thiourea and subsequent oxidative chlorination of the ob
Autor:
Valentyna O. Pivnytska, Yevheniia Markushyna, Yuliya Tokaryeva, Günter Haufe, Oleksandr O. Grygorenko, Maria Kliachyna, Ivan G. Logvinenko, Ivan S. Kondratov, Bohdan V. Vashchenko
Publikováno v:
Journal of Fluorine Chemistry. 231:109461
Effects of the trifluoromethoxy substituent on physico-chemical properties of compounds, such as kinetic solubility, lipophilicity and microsomal clearance, was studied in a series of aliphatic derivatives. It was found that kinetic solubility of the
Autor:
Ivan S, Kondratov, Ivan G, Logvinenko, Nataliya A, Tolmachova, Roman N, Morev, Maria A, Kliachyna, Florian, Clausen, Constantin G, Daniliuc, Günter, Haufe
Publikováno v:
Organicbiomolecular chemistry. 15(3)
2-Amino-2-(trifluoromethoxy)butanoic acid (O-trifluoromethyl homoserine) was synthesized as a racemate and in both enantiomeric forms. The measured pK