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Dystrophin Deficiency Leads to Genomic Instability in Human Pluripotent Stem Cells via NO Synthase-Induced Oxidative Stress

Autor: Sarka Jelinkova, Petr Fojtik, Aneta Kohutova, Aleksandra Vilotic, Lenka Marková, Martin Pesl, Tereza Jurakova, Miriama Kruta, Jan Vrbsky, Renata Gaillyova, Iveta Valášková, Ivan Frák, Alain Lacampagne, Giancarlo Forte, Petr Dvorak, Albano C. Meli, Vladimir Rotrekl

Publikováno v: Cells, Vol 8, Iss 1, p 53 (2019)

Recent data on Duchenne muscular dystrophy (DMD) show myocyte progenitor’s involvement in the disease pathology often leading to the DMD patient’s death. The molecular mechanism underlying stem cell impairment in DMD has not been described. We cr

Externí odkaz: https://doaj.org/article/281f75eead514e94bca7293ac89a6fc7

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Dystrophin Deficiency Leads to Genomic Instability in Human Pluripotent Stem Cells via NO Synthase-Induced Oxidative Stress

Autor: Martin Pešl, Jan Vrbsky, Renata Gaillyová, Lenka Marková, Aleksandra Vilotić, Ivan Frák, Giancarlo Forte, Albano C. Meli, Iveta Valášková, Alain Lacampagne, Aneta Kohutova, Miriama Krutá, Tereza Jurakova, Petr Dvorak, Vladimír Rotrekl, Petr Fojtík, Šárka Jelínková

Publikováno v: Cells
Cells, MDPI, 2019, 8 (1), pp.53. ⟨10.3390/cells8010053⟩
Volume 8
Issue 1
Cells, Vol 8, Iss 1, p 53 (2019)
Cells, 2019, 8 (1), pp.53. ⟨10.3390/cells8010053⟩

International audience; Recent data on Duchenne muscular dystrophy (DMD) show myocyte progenitor’s involvement in the disease pathology often leading to the DMD patient’s death. The molecular mechanism underlying stem cell impairment in DMD has n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67a1a64496f8a2c22a21e0860cd62f87
https://hal.archives-ouvertes.fr/hal-01986076

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