Zobrazeno 1 - 10
of 215
pro vyhledávání: '"Ivan Da Rocha Pitta"'
Autor:
Juliana Machado Kayser, Gabriela Zimmermann Prado Rodrigues, Carlos Henrique Thomazi, Alana Witt Hansen, Marina Griebeler Moreira, Marina Galdino da Rocha Pitta, Ivan da Rocha Pitta, Ana Luiza Ziulkoski, Andresa Heemann Betti
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 59 (2023)
Abstract Schizophrenia is an illness that affects 26 million people worldwide. However, conventional antipsychotics present side effects and toxicity, highlighting the need for new antipsychotics. We aimed to evaluate the cytotoxicity of haloperidol
Externí odkaz:
https://doaj.org/article/6a59cc5dc8424582abe143045f3108d3
Autor:
Michael Williams Leal Quirino, Michelly Cristiny Pereira, Maria de Fátima Deodato de Souza, Ivan da Rocha Pitta, Antônio Felix da Silva Filho, Mario S. de Souza Albuquerque, Amanda Pinheiro de Barros Albuquerque, Mário Rino Martins, Maira Galdino da Rocha Pitta, Moacyr Jesus Barreto de Melo Rêgo
Publikováno v:
European Journal of Histochemistry, Vol 65, Iss 1 (2021)
The sialic acid-binding immunoglobulin-type lectin Siglec-15 is a promising target to cancer immunotherapy in several tumor types. The present study aimed to investigate Siglec-15 expression in gastric cancer (GC) patient tissue and to evaluate its c
Externí odkaz:
https://doaj.org/article/e7b46fa70a784e099e27d66235631b08
Autor:
Pablo Ramon Gualberto Cardoso, Claudia Diniz Lopes Marques, Kamila de Melo Vilar, Andrea Tavares Dantas, Angela Luzia Branco Pinto Duarte, Ivan da Rocha Pitta, Maira Galdino da Rocha Pitta, Moacyr Jesus Barreto de Melo Rêgo
Publikováno v:
Autoimmune Diseases, Vol 2021 (2021)
Objectives. Rheumatoid arthritis affects about 1% of the world’s population. This is a chronic autoimmune disease. It is predominant in females with progressive joint damage. Immune cells are involved, especially Th1/Th17 lymphocytes and their infl
Externí odkaz:
https://doaj.org/article/fa728f11e7974578a64ceebe6f203126
Autor:
Kamila de Melo Vilar, Michelly Cristiny Pereira, Andrea Tavares Dantas, Moacyr Jesus Barreto de Melo Rêgo, Ivan da Rocha Pitta, Ângela Luzia Branco Pinto Duarte, Maira Galdino da Rocha Pitta
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0223191 (2019)
IntroductionRheumatoid arthritis (RA) is a chronic autoimmune disease characterized by synovial inflammation and hyperplasia, as well as cartilage and bone destruction. Several proteins are associated with the pathogenesis of the disease. Galectin-9
Externí odkaz:
https://doaj.org/article/9766edfbec7b4be0ac1dc374123b8289
Autor:
Kamila de Melo Vilar, Michelly Cristiny Pereira, Andrea Tavares Dantas, Moacyr Jesus Barreto de Melo Rêgo, Ivan da Rocha Pitta, Claudia Diniz Lopes Marques, Rafaela Silva Guimarães Gonçalves, Laurindo Ferreira da Rocha Júnior, Ângela Luzia Branco Pinto Duarte, Maira Galdino da Rocha Pitta
Publikováno v:
Autoimmune Diseases, Vol 2019 (2019)
Background. Due to the variety of functions that galectins (Gal) possess, it is clear that they participate in the pathogenesis of rheumatoid arthritis (RA). Although some studies demonstrate their functions, there is still no correlation with the cl
Externí odkaz:
https://doaj.org/article/7bd166bdd45e43d588b6ba5b5ec322df
Autor:
Moacyr Jesus Barreto de Melo Rêgo, Adriana Azoubel-Antunes, Mariana Brayner-Cavalcanti Freire Bezerra, Michelly Cristiny Pereira, Juliana Cruz da Silva, Thiago Ubiratan Lins e Lins, Emanuel Sávio Cavalcanti Sarinho, Cézar Augusto da Cruz Amorim, Maria do Carmo Alves de Lima, Marina Rocha Galdino-Pitta, Ivan da Rocha Pitta, Maira Galdino da Rocha Pitta
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 54, Iss 3 (2018)
Allergic asthma is a chronic, complex inflammatory disease of the airway. Despite extensive studies on the immunomodulation of T helper (Th) cell pathways (i.e., Th1 and Th2) in asthma, little is known about the effects of Th17 pathway modulation, pa
Externí odkaz:
https://doaj.org/article/3f9ff315621a42929eec2f36e4a96881
Autor:
Elizabeth Almeida Lafayette, Sinara Mônica Vitalino de Almeida, Marina Galdino da Rocha Pitta, Eduardo Isidoro Carneiro Beltrão, Teresinha Gonçalves da Silva, Ricardo Olímpio de Moura, Ivan da Rocha Pitta, Luiz Bezerra de Carvalho, Maria do Carmo Alves de Lima
Publikováno v:
Molecules, Vol 18, Iss 12, Pp 15035-15050 (2013)
Thiazacridine and imidazacridine derivatives have shown promising results as tumors suppressors in some cancer cell lines. For a better understanding of the mechanism of action of these compounds, binding studies of 5-acridin-9-ylmethylidene-3-amino-
Externí odkaz:
https://doaj.org/article/0429fba2111540dfab4ef395fa284c43
Autor:
Juliana Cruz da Silva, Henrique Ataide Mariz, Laurindo Ferreira da Rocha Júnior, Priscilla Stela Santana de Oliveira, Andrea Tavares Dantas, Angela Luzia Branco Pinto Duarte, Ivan da Rocha Pitta, Suely Lins Galdino, Maira Galdino da Rocha Pitta
Publikováno v:
Clinics, Vol 68, Iss 6, Pp 766-771 (2013)
OBJECTIVES: Hydroxychloroquine is an antimalarial agent that has been used in systemic lupus erythematosus and rheumatoid arthritis treatment for many years. Recently, novel mechanisms of action have been proposed, thereby broadening the therapeutic
Externí odkaz:
https://doaj.org/article/6fcb48efd9c846adb0f0838e4246184b
Autor:
Priscilla Stela Santana de Oliveira, Michelly Cristiny Pereira, Simão Kalebe Silva de Paula, Emerson Vasconcelos Andrade Lima, Mariana Modesto de Andrade Lima, Rodrigo Gomes de Arruda, Wagner Luís Mendes de Oliveira, Ângela Luzia Branco Pinto Duarte, Ivan da Rocha Pitta, Moacyr Jesus Melo Barreto Rêgo, Maira Galdino da Rocha Pitta
Publikováno v:
Mediators of Inflammation, Vol 2016 (2016)
Psoriasis is a chronic and recurrent dermatitis, mediated by keratinocytes and T cells. Several proinflammatory cytokines contribute to formation and maintenance of psoriatic plaque. The Th1/Th17 pathways and some of IL-1 family members were involved
Externí odkaz:
https://doaj.org/article/3ce1c4c7a9924d23ac65028612d10136
Autor:
Ricardo Olímpio de Moura, Rayssa Marques Duarte da Cruz, Francisco Jaime Bezerra Mendonça, Jaismary Gonzaga Batista de Oliveira, Edeltrudes de Oliveira Lima, Marcelo Sobral da Silva, Maria do Carmo Alves de Lima, Ivan da Rocha Pitta, Luciana Scotti, Marcus Tullius Scotti
Publikováno v:
Molecules, Vol 17, Iss 3, Pp 2298-2315 (2012)
Fifty 2-[(arylidene)amino]-4,5-cycloalkyl[b]thiophene-3-carbonitrile derivatives were screened for their in vitro antifungal activities against Candida krusei and Cryptococcus neoformans. Based on experimentally determined minimum inhibitory concentr
Externí odkaz:
https://doaj.org/article/fafff51608ce4c5ebce67cdc0a658e8d