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Akademický článek
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Autor:
Gordon Williams, Anthony N. Warrens, Robert J. Eckersley, Martin J. K. Blomley, Ivan Berton, Finn Morgan, Madeleine Lynch, Paul E. Herbert
Publikováno v:
Transplantation. 79:731-734
The narrow therapeutic window of cyclosporine A (CsA) means its use is controlled by pharmacokinetic monitoring. However, pharmacokinetics do not always reflect the functional effects of a drug--its pharmacodynamics, such as vasoconstriction. We deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9b5dc67a619f10c23925f94212fd5f2
https://doi.org/10.1097/01.tp.0000154916.71990.31
https://doi.org/10.1097/01.tp.0000154916.71990.31
Autor:
Paul E. Herbert, Robert I. Lechler, Ivan Berton, Anthony Dorling, M. Finn Morgan, Anthony N. Warrens, Gordon Williams
Publikováno v:
Transplant immunology. 19(3-4)
Allograft rejection caused by antibodies in sensitised individuals remains a real problem in human allotransplantation. There would be value in a simple model of this process to evaluate the mechanisms involved in antibody-mediated damage and the dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23baf673126eaa6ce9b8c1a94a3bedfe
https://pubmed.ncbi.nlm.nih.gov/18621532
https://pubmed.ncbi.nlm.nih.gov/18621532
Autor:
Ivan Berton, Joseph Read, Vincenzo Mirenda, Anthony Dorling, Anthony N. Warrens, Dela Golshayan, Robert I. Lechler
Publikováno v:
King's College London
Recent success in pancreatic islet allotransplantation has raised expectations but has equally highlighted the acute shortage of donor tissue. The use of xenogeneic tissue would help to address this shortage; however, strong cellular immunity limits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d42ce80b8c51f1faa8245106e2bed1f
https://pubmed.ncbi.nlm.nih.gov/15793243
https://pubmed.ncbi.nlm.nih.gov/15793243
Autor:
Ivan Berton, Paul E. Herbert, Daxin Chen, Gordon Williams, Anthony Dorling, Finn Morgan, Robert I. Lechler, Anthony N. Warrens
Publikováno v:
Transplantation. 77(9)
The pig is generally regarded as likely to be the preferred donor animal in xenotransplantation. Although many hurdles remain to be cleared, it would be useful to be able to manipulate porcine endothelium genetically, among other reasons, to test app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0ee76b9793dc44b31731514e47fe413
https://pubmed.ncbi.nlm.nih.gov/15167604
https://pubmed.ncbi.nlm.nih.gov/15167604
Autor:
Anthony Dorling, Robert I. Lechler, Vincenzo Mirenda, Ivan Berton, Joseph Read, Jennifer A. Smith, Terence Cook
Publikováno v:
Journal of the American Society of Nephrology : JASN. 15(4)
A feature of the tolerance that has been described in experimental models is that it can be transferred by CD4+ T cells to a naive recipient. Described is a novel approach to induce indirect pathway regulatory T cells in a rat model that exploits the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9894366fa2620b72aa79904f7390987
https://pubmed.ncbi.nlm.nih.gov/15034118
https://pubmed.ncbi.nlm.nih.gov/15034118
Autor:
Nigel Farrow, Patricia Cmielewski, Martin Donnelley, Nathan Rout-Pitt, Yuben Moodley, Ivan Bertoncello, David Parsons
Publikováno v:
Stem Cell Research & Therapy, Vol 9, Iss 1, Pp 1-8 (2018)
Abstract Background Airway disease is a primary cause of morbidity and early mortality for patients with cystic fibrosis (CF). Cell transplantation therapy has proven successful for treating immune disorders and may have the potential to correct the
Externí odkaz:
https://doaj.org/article/6e0a5ca029d24cec9546c61078b55b9b
Autor:
Paul E Herbert, Madeleine Lynch, Finn Morgan, Ivan Berton, Robert Eckersley, Gordon Williams, Martin Blomley, Anthony N Warrens
Publikováno v:
Transplantation; Mar2005, Vol. 79 Issue 6, p731-734, 4p
Autor:
Duy Huynh, Dilara Akçora, Jordane Malaterre, Chee Kai Chan, Xu-Ming Dai, Ivan Bertoncello, E Richard Stanley, Robert G Ramsay
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56951 (2013)
The colony stimulating factor-1 (CSF-1) receptor (CSF-1R) directly regulates the development of Paneth cells (PC) and influences proliferation and cell fate in the small intestine (SI). In the present study, we have examined the role of CSF-1 and the
Externí odkaz:
https://doaj.org/article/c45b212324d94dff91378f1490c961b5
Autor:
Huiling Xu, Kuhendra Balakrishnan, Jordane Malaterre, Matthew Beasley, Yuqian Yan, Jeroen Essers, Esther Appeldoorn, Jonathan M Tomaszewski, Melisa Vazquez, Sandra Verschoor, Martin F Lavin, Ivan Bertoncello, Robert G Ramsay, Michael J McKay
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12112 (2010)
Approximately half of cancer-affected patients receive radiotherapy (RT). The doses delivered have been determined upon empirical experience based upon average radiation responses. Ideally higher curative radiation doses might be employed in patients
Externí odkaz:
https://doaj.org/article/b79e9ce7fa214852a1af1b3ada47981f