Výsledky vyhledávání

The small heat shock proteins, HSPB1 and HSPB5, interact differently with lipid membranes

Autor: Nelson Arispe, Ivan Bello, Ricardo Capone, Wilbert C. Boelens, Wilma Vree Egberts, Antonio De Maio, David M. Cauvi

Publikováno v: Cell stress & chaperones, vol 24, iss 5

Increasing evidence shows that heat shock proteins (hsp) escape the cytosol gaining access to the extracellular environment, acting as signaling agents. Since the majority of these proteins lack the information necessary for their export via the clas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::968ab03279508bf97daa4518e6772ed2
https://europepmc.org/articles/PMC6717221/

Zobrazit plný text záznamu

Econometric model for the Chilean economy

Autor: Ivan Bello

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::633ba7797dff58c7e8d693f74d2f985c
https://doi.org/10.31274/rtd-180813-6442

Zobrazit plný text záznamu

Multidrug resistance (MDR) reversers: High activity and efficacy in a series of asymmetrical N,N-bis(alkanol)amine aryl esters

Autor: Cristina Bellucci, Elisa Floriddia, Elisabetta Teodori, Marcella Coronnello, Milena Salerno, Dina Manetti, Silvia Dei, Enrico Mini, Maria Novella Romanelli, Ivan Bello, Gianluca Bartolucci, Luca Guandalini

Publikováno v: European Journal of Medicinal Chemistry. 87:398-412

As a continuation of our research on potent and efficacious P-gp-dependent multidrug resistance (MDR) reversers, several new N , N -bis(alkanol)amine aryl esters were designed and synthesized, varying the aromatic moieties or the length of the methyl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37cbdd8f4430c2737d620f53af06cda9
https://doi.org/10.1016/j.ejmech.2014.09.084

Zobrazit plný text záznamu

New structure–activity relationship studies in a series of N,N-bis(cyclohexanol)amine aryl esters as potent reversers of P-glycoprotein-mediated multidrug resistance (MDR)

Autor: Enrico Mini, Francesca Orlandi, Luca Guandalini, Cecilia Martelli, Serena Scapecchi, Elisabetta Teodori, Ivan Bello, Maria Novella Romanelli, Cristina Bellucci, Marcella Coronnello, Silvia Dei, Dina Manetti, Hayette Menif, Milena Salerno

Publikováno v: Bioorganic & Medicinal Chemistry. 21:456-465

As a continuation of previous research on a new series of potent and efficacious P-gp-dependent multidrug resistant (MDR) reversers with a N,N -bis(cyclohexanol)amine scaffold, we have designed and synthesized several analogs by modulation of the two

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc936c5ee01576d3370be882033f1f72
https://doi.org/10.1016/j.bmc.2012.11.019

Zobrazit plný text záznamu

Evidence against a role of P-glycoprotein in the clearance of the Alzheimer's disease Aβ1-42 peptides

Autor: Milena Salerno, Ivan Bello

Publikováno v: Cell stresschaperones. 20(3)

It has been proposed that the amyloid-β peptides (Aβ) cause the neuronal degeneration in the Alzheimer’s disease brain. An imbalance between peptide production at the neuronal level and their elimination across the blood–brain–barrier (BBB) r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bef2590a715980598fbf9ac29a968144
https://pubmed.ncbi.nlm.nih.gov/25591827

Zobrazit plný text záznamu