Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Ivan B. Lomakin"'
Scientific Rationale and Clinical Basis for Clindamycin Use in the Treatment of Dermatologic Disease
Publikováno v:
Antibiotics, Vol 13, Iss 3, p 270 (2024)
Clindamycin is a highly effective antibiotic of the lincosamide class. It has been widely used for decades to treat a range of skin and soft tissue infections in dermatology and medicine. Clindamycin is commonly prescribed for acne vulgaris, with cur
Externí odkaz:
https://doaj.org/article/1d589a55298f41ec947c47fb03d7eef9
Autor:
Swapnil C. Devarkar, Michael Vetick, Shravani Balaji, Ivan B. Lomakin, Luojia Yang, Danni Jin, Wendy V. Gilbert, Sidi Chen, Yong Xiong
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113156- (2023)
Summary: All betacoronaviruses (β-CoVs) encode non-structural protein 1 (Nsp1), an essential pathogenicity factor that potently restricts host gene expression. Among the β-CoV family, MERS-CoV is the most distantly related member to SARS-CoV-2, and
Externí odkaz:
https://doaj.org/article/ea492ca260034be5a86d60d71e01573b
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 696-704 (2020)
The density regulated protein (DENR) forms a stable heterodimer with malignant T-cell-amplified sequence 1 (MCT-1). DENR-MCT-1 heterodimer then participates in regulation of non-canonical translation initiation and ribosomal recycling. The N-terminal
Externí odkaz:
https://doaj.org/article/77f8f555aa5347509ede3aa1f6656ea8
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Coronaviruses have brought severe challenges to public health all over the world in the past 20years. SARS-CoV-2, the causative agent of the COVID-19 pandemic that has led to millions of deaths, belongs to the genus beta-coronavirus. Alpha- and beta-
Externí odkaz:
https://doaj.org/article/75717fdc572d4df1baefe86cb25e5047
Autor:
Ivan B. Lomakin, Elena A. Stolboushkina, Anand T. Vaidya, Chenguang Zhao, Maria B. Garber, Sergey E. Dmitriev, Thomas A. Steitz
Publikováno v:
Cell Reports, Vol 20, Iss 3, Pp 521-528 (2017)
The repertoire of the density-regulated protein (DENR) and the malignant T cell-amplified sequence 1 (MCT-1/MCTS1) oncoprotein was recently expanded to include translational control of a specific set of cancer-related mRNAs. DENR and MCT-1 form the h
Externí odkaz:
https://doaj.org/article/babaff4811b1428283ded45043300c7c
Publikováno v:
International Journal of Biomedicine, Vol 9, Iss Suppl_1, Pp S24-S24 (2019)
The last stage of translation cycle is ribosome recycling which occurs after completed polypeptide is released. This step comprises dissociation of 60S ribosomal subunit, followed by tRNA and mRNA removal from the 40S-tRNA-mRNA post-termination compl
Externí odkaz:
https://doaj.org/article/1723de67ab924e5aaf67168a89dee4c1
Publikováno v:
Nucleic Acids Research. 51:2915-2930
Acne vulgaris is a chronic disfiguring skin disease affecting ∼1 billion people worldwide, often having persistent negative effects on physical and mental health. The Gram-positive anaerobe, Cutibacterium acnes is implicated in acne pathogenesis an
Autor:
Anna deFazio, David D.L. Bowtell, Ivan B. Lomakin, Helen Rizos, Martin Köbel, Sean M. Grimmond, Nicola Waddell, John V. Pearson, Timothy Semple, Timothy P. Holloway, Gisela Mir Arnau, George Au-Yeung, Joshy George, Ann-Marie Patch, Elizabeth L. Christie, Jason Li, Paul R. Harnett, Raghwa Sharma, Joy Hendley, Yoke-Eng Chiew, Chris Mitchell, Sian Fereday, Catherine J. Kennedy, Dale W. Garsed, Tania Moujaber, Ying Lei, Walid J. Azar, Dariush Etemadmoghadam
Low-grade serous ovarian carcinomas (LGSC) are associated with a poor response to chemotherapy and are molecularly characterized by RAS pathway activation. Using exome and whole genome sequencing, we identified recurrent mutations in the protein tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de61d8a9c700ed14b683350e2bb143e6
https://doi.org/10.1158/0008-5472.c.6509045.v1
https://doi.org/10.1158/0008-5472.c.6509045.v1
Autor:
Anna deFazio, David D.L. Bowtell, Ivan B. Lomakin, Helen Rizos, Martin Köbel, Sean M. Grimmond, Nicola Waddell, John V. Pearson, Timothy Semple, Timothy P. Holloway, Gisela Mir Arnau, George Au-Yeung, Joshy George, Ann-Marie Patch, Elizabeth L. Christie, Jason Li, Paul R. Harnett, Raghwa Sharma, Joy Hendley, Yoke-Eng Chiew, Chris Mitchell, Sian Fereday, Catherine J. Kennedy, Dale W. Garsed, Tania Moujaber, Ying Lei, Walid J. Azar, Dariush Etemadmoghadam
Supplemental Material - Group Authorship from EIF1AX and NRAS Mutations Co-occur and Cooperate in Low-Grade Serous Ovarian Carcinomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::027e670cd644246a5a5453c1a27413c2
https://doi.org/10.1158/0008-5472.22414655.v1
https://doi.org/10.1158/0008-5472.22414655.v1
Autor:
Anna deFazio, David D.L. Bowtell, Ivan B. Lomakin, Helen Rizos, Martin Köbel, Sean M. Grimmond, Nicola Waddell, John V. Pearson, Timothy Semple, Timothy P. Holloway, Gisela Mir Arnau, George Au-Yeung, Joshy George, Ann-Marie Patch, Elizabeth L. Christie, Jason Li, Paul R. Harnett, Raghwa Sharma, Joy Hendley, Yoke-Eng Chiew, Chris Mitchell, Sian Fereday, Catherine J. Kennedy, Dale W. Garsed, Tania Moujaber, Ying Lei, Walid J. Azar, Dariush Etemadmoghadam
Supplemental materials and methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e83d93261f5411fcf3af9e9ea03cb1b
https://doi.org/10.1158/0008-5472.22414652.v1
https://doi.org/10.1158/0008-5472.22414652.v1