Zobrazeno 1 - 6 of 6 pro vyhledávání: '"Ivan B. Cheglakov"'
1
Combined treatment, based on lysomustine administration with mesenchymal stem cells expressing cytosine deaminase therapy, leads to pronounced murine Lewis lung carcinoma growth inhibition
Autor: Ivan B. Cheglakov, Saida S. Karshieva, A. V. Belyavsky, Lyudmila S. Krassikova
Publikováno v: The Journal of Gene Medicine. 18:220-233
Background The combination of stem cell-based gene therapy with chemotherapy comprises an advantageous strategy that results in a reduction of system toxicity effects and an improvement in the general efficacy of treatment. In the present study, we e
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dee09c5d139c83ab5fda1c0ae2d28d59
https://doi.org/10.1002/jgm.2894
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2
Combined treatment, based on lysomustine administration with mesenchymal stem cells expressing cytosine deaminase therapy, leads to pronounced murine Lewis lung carcinoma growth inhibition
Autor: Lyudmila S, Krassikova, Saida S, Karshieva, Ivan B, Cheglakov, Alexander V, Belyavsky
Publikováno v: The journal of gene medicine. 18(9)
The combination of stem cell-based gene therapy with chemotherapy comprises an advantageous strategy that results in a reduction of system toxicity effects and an improvement in the general efficacy of treatment. In the present study, we estimated th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::425adc1c0886e042e09d9750107bca64
https://pubmed.ncbi.nlm.nih.gov/27461566
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3
Peripherally Applied Synthetic Tetrapeptides HAEE and RADD Slow Down the Development of Cerebral β-Amyloidosis in AβPP/PS1 Transgenic Mice
Autor: Georgy B. Telegin, Ivan B. Cheglakov, Sergey A. Kozin, Alexander Morozov, Philipp O. Tsvetkov, Oleg Mediannikov, Armen A. Ovsepyan
Publikováno v: Journal of Alzheimer's Disease
Journal of Alzheimer's Disease, IOS Press, 2016, pp.20-20. ⟨10.3233/JAD-150031⟩
International audience; Two tetrapeptides, HAEE and RADD, which are ionic-complementary to the primary zinc recognition site of amyloid-(A), have been reported to inhibit zinc-induced dimerization of the A metal-binding domain and slow A aggregation
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b96531029fabe6eac5eac9353d41c3b6
https://doi.org/10.3233/JAD-150031
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5
Blockade of receptor-operated calcium channels by mibefradil (Ro 40-5967): effects on intracellular calcium and platelet aggregation
Autor: Vsevolod A. Tkachuk, Valery N. Bochkov, Martina Hahn, Jean-Paul Clozel, Ivan B. Cheglakov
Publikováno v: Cardiovascular drugs and therapy. 9(6)
The goal of the present study was to evaluate if mibefradil, a novel nondihydropyridine Ca2+ antagonist, could block receptor-operated calcium channels (ROCC) present in human platelets and to determine the functional consequences of this blockade. T
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87224692368e8cff3acfe5cab3327ccf
https://pubmed.ncbi.nlm.nih.gov/8850387
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6
Stimulation of non-selective cation channels providing Ca2+ influx into platelets by platelet-activating factor and other aggregation inducers
Autor: Pavel V. Avdonin, Ivan B. Cheglakov, Vsevolod A. Tkachuk
Publikováno v: European journal of biochemistry. 198(1)
To elucidate the mechanism of the receptor-stimulated Ca2+ entry into human platelets, the influence of Ca(2+)-mobilizing agonists on plasma membrane potential (Em) has been studied. Em changes were registered using potentiometric probe 3,3'-dipropyl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1ab1effc3f3a08fd08e737a92a4a0ab
https://pubmed.ncbi.nlm.nih.gov/1710183
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