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Publikováno v:
In Biochimie July 2020 174:136-143
Akademický článek
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Akademický článek
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Autor:
Radovčić, Marin, Ivančić-Baće, Ivana
Insertion of new spacers into the CRISPR locus of many bacteria or archaea enables their protection from invading DNA elements. This process is called naïve adaptation and is catalysed by the Cas1-Cas2 complex only. Fragmentation of invading DNA pri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::af91031b3e71074a1adec1bcf165f027
https://www.bib.irb.hr/1278144
https://www.bib.irb.hr/1278144
Publikováno v:
In Journal of Molecular Biology 5 October 2012 422(5):607-616
To protect themselves from invasive mobile genetic elements (MGE), prokaryotes have developed many defense strategies. The CRISPR-Cas adaptive immune system allows prokaryotes to defend themselves by memorizing, recognizing and destroying MGEs. The m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::f71f7b28682822b3e769447266714781
https://www.bib.irb.hr/1197248
https://www.bib.irb.hr/1197248
Autor:
Ivančić Baće, Ivana
Protein Cas3 je nukleaza-helikaza koja cijepa jednolančanu (ss) DNA i neophodna je u zadnjem koraku zaštite bakterija od napada stranom DNA obrambenim sustavom CRISPR-Cas. Kristalna struktura proteina Cas3 pokazala je da na putu do nukleaznog aktiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::73a71883968056224fcab0ee663b0bff
https://www.bib.irb.hr/1197238
https://www.bib.irb.hr/1197238
Autor:
Mitić, Damjan, Ivančić Baće, Ivana
Adaptivni imunološki sustav CRISPR-Cas štiti mnoge bakterije i većinu arheja od strane DNA. Sustav CRISPR-Cas u bakteriji Escherichia coli pripada klasi 1, tipu I-E, a sastoji se od 8 gena cas i dva lokusa CRISPR. Tri promotora kontroliraju ekspre
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https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::c7cc1cd5db69f2eb4d53c67d3c4166d1
https://www.bib.irb.hr/1256613
https://www.bib.irb.hr/1256613
Autor:
He, Liu, Jelić Matošević, Zoe, Mitić, Damjan, Markulin, Dora, Killelea, Tom, Matković, Mrija, Bertoša, Branimir, Ivančić-Baće, Ivana and Bolt, Edward L.
Cas3 is a ssDNA-targeting nuclease-helicase essential for class 1 prokaryotic CRISPR immunity systems. Cas3-DNA crystal structures show that ssDNA follows a pathway from helicase domains through to a HD-nuclease active site, requiring protein conform
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https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::8f6137a3d8ebbe1ce50f31633637d829
https://www.bib.irb.hr/1137474
https://www.bib.irb.hr/1137474
Clustered regularly interspaced short palindromic repeats – CRISPR associated genes (CRISPR-Cas) is a prokaryotic defence system that protects against phage infection and foreign DNA, such as plasmids. It is comprised of cas protein genes and the C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::392fb204ebc3bba963094a8c8d170101
https://www.bib.irb.hr/1147549
https://www.bib.irb.hr/1147549