Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Ivan, Hemeon"'
Autor:
Brian S, Safina, Steven J, McKerrall, Shaoyi, Sun, Chien-An, Chen, Sultan, Chowdhury, Qi, Jia, Jun, Li, Alla Y, Zenova, Jean-Christophe, Andrez, Girish, Bankar, Philippe, Bergeron, Jae H, Chang, Elaine, Chang, Jun, Chen, Richard, Dean, Shannon M, Decker, Antonio, DiPasquale, Thilo, Focken, Ivan, Hemeon, Kuldip, Khakh, Amy, Kim, Rainbow, Kwan, Andrea, Lindgren, Sophia, Lin, Jonathan, Maher, Janette, Mezeyova, Dinah, Misner, Karen, Nelkenbrecher, Jodie, Pang, Rebecca, Reese, Shannon D, Shields, Luis, Sojo, Tao, Sheng, Henry, Verschoof, Matthew, Waldbrook, Michael S, Wilson, Zhiwei, Xie, Clint, Young, Tanja S, Zabka, David H, Hackos, Daniel F, Ortwine, Andrew D, White, J P, Johnson, C Lee, Robinette, Christoph M, Dehnhardt, Charles J, Cohen, Daniel P, Sutherlin
Publikováno v:
Journal of medicinal chemistry. 64(6)
Na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d744b2a5894fa87236be1caf92c75b8b
https://pubmed.ncbi.nlm.nih.gov/33682420
https://pubmed.ncbi.nlm.nih.gov/33682420
Autor:
Shaoyi, Sun, Qi, Jia, Alla Y, Zenova, Michael S, Wilson, Sultan, Chowdhury, Thilo, Focken, Jun, Li, Shannon, Decker, Michael E, Grimwood, Jean-Christophe, Andrez, Ivan, Hemeon, Tao, Sheng, Chien-An, Chen, Andy, White, David H, Hackos, Lunbin, Deng, Girish, Bankar, Kuldip, Khakh, Elaine, Chang, Rainbow, Kwan, Sophia, Lin, Karen, Nelkenbrecher, Benjamin D, Sellers, Antonio G, DiPasquale, Jae, Chang, Jodie, Pang, Luis, Sojo, Andrea, Lindgren, Matthew, Waldbrook, Zhiwei, Xie, Clint, Young, James P, Johnson, C Lee, Robinette, Charles J, Cohen, Brian S, Safina, Daniel P, Sutherlin, Daniel F, Ortwine, Christoph M, Dehnhardt
Publikováno v:
Journal of medicinal chemistry. 62(2)
Herein, we report the discovery and optimization of a series of orally bioavailable acyl sulfonamide Na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::038f23a54877cc0c450b0a4b2689f99c
https://pubmed.ncbi.nlm.nih.gov/30499663
https://pubmed.ncbi.nlm.nih.gov/30499663
Autor:
Thilo, Focken, Sultan, Chowdhury, Alla, Zenova, Michael E, Grimwood, Christine, Chabot, Tao, Sheng, Ivan, Hemeon, Shannon M, Decker, Michael, Wilson, Paul, Bichler, Qi, Jia, Shaoyi, Sun, Clint, Young, Sophia, Lin, Samuel J, Goodchild, Noah G, Shuart, Elaine, Chang, Zhiwei, Xie, Bowen, Li, Kuldip, Khakh, Girish, Bankar, Matthew, Waldbrook, Rainbow, Kwan, Karen, Nelkenbrecher, Parisa, Karimi Tari, Navjot, Chahal, Luis, Sojo, C Lee, Robinette, Andrew D, White, Chien-An, Chen, Yi, Zhang, Jodie, Pang, Jae H, Chang, David H, Hackos, J P, Johnson, Charles J, Cohen, Daniel F, Ortwine, Daniel P, Sutherlin, Christoph M, Dehnhardt, Brian S, Safina
Publikováno v:
Journal of medicinal chemistry. 61(11)
The sodium channel Na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::41b8d0a60c84d4f1a2c37587e6288037
https://pubmed.ncbi.nlm.nih.gov/29737846
https://pubmed.ncbi.nlm.nih.gov/29737846
Publikováno v:
Analytical Chemistry. 83:4996-5004
DNA (cytosine-5)-methyltransferases (DNMTs) catalyze the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to the 5-position of cytosine residues and thereby silence transcription of regulated genes. DNMTs are important epigenetic targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fae7937b03c797ca5bbefa538ec64563
https://doi.org/10.1021/ac200816m
https://doi.org/10.1021/ac200816m
Autor:
Emilio F. Merino, Ivan Hemeon, Vern L. Schramm, Joseph Locker, Chandan Guha, Gary B. Evans, Indranil Basu, Maria B. Cassera, X. Dong, Thomas J. Belbin
Publikováno v:
Journal of Biological Chemistry. 286:4902-4911
The S-adenosylmethionine (AdoMet) salvage enzyme 5'-methylthioadenosine phosphorylase (MTAP) has been implicated as both a cancer target and a tumor suppressor. We tested these hypotheses in mouse xenografts of human lung cancers. AdoMet recycling fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4db4095ab3858e0b6f675b346ba2731c
https://doi.org/10.1074/jbc.m110.198374
https://doi.org/10.1074/jbc.m110.198374
Autor:
Ivan Hemeon, Andrew J. Bennet
Publikováno v:
Canadian Journal of Chemistry. 86:238-247
A useful, unexpected β,γ-unsaturated-α-keto ester (ethyl (E)-5-acetamido-3,4,5-trideoxy-6,7:8,9-di-O- isopropylidene-D-manno-non-3-en-2-ulosonate 5) was isolated in 91% yield following ozonolysis and chromatographic purification of its enoate este
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::faeffadf064c4fd6a847fc3fdcf9f5b9
https://doi.org/10.1139/v08-006
https://doi.org/10.1139/v08-006
Autor:
Andrew J. Bennet, Ivan Hemeon
Publikováno v:
Synthesis. 2007:1899-1926
Sialic acid ( N-acetylneuraminic acid) is a carbohydrate that is often found on the ends of oligosaccharide chains in biological systems. As such, it is important in several biological recognition/communication events mediated by sialic acid recognis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41f4f3ea22c350442fb059188bbc1896
https://doi.org/10.1055/s-2007-983723
https://doi.org/10.1055/s-2007-983723
Autor:
Ivan Hemeon, Robert D. Singer
Publikováno v:
Journal of Molecular Catalysis A: Chemical. 214:33-44
The palladium(0)-catalysed addition of silylstannanes Bu3SnSiMe3 and Bu3SnSiMe2Ph to terminal alkynes has been shown to proceed in the ionic liquids 1-n-butyl-3-methylimidazolium hexafluorophosphate ([bmim]PF6) and 1-n-butyl-3-methylimidazolium tetra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6456b0cf10626aabffcf1c34a5722b2d
https://doi.org/10.1016/j.molcata.2003.09.032
https://doi.org/10.1016/j.molcata.2003.09.032
Publikováno v:
Synlett. 2002:1815-1818
Diels-Alder reactions of the heteroaromatic diene furan proceed with enhanced isolated yields and reversal of endo/exo selectivity (2:1 endo vs exo) in the ionic liquids [bmim]BF 4 and [bmim]PF 6 compared to conventional methods. The potential utilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c55e4079d8fee39be174f6485cb227b
https://doi.org/10.1055/s-2002-34868
https://doi.org/10.1055/s-2002-34868
Publikováno v:
Tetrahedron Letters. 41:1343-1346
Ionic liquids derived from 1-ethyl-3-methylimidazolium iodide (emimI), and aluminium chloride have been shown to be suitable solvents for the acylative cleavage of a series of cyclic and acyclic ethers. Difunctionalised ω-iodobenzoate adducts have b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6e7382ecb2f2044477eb75c30a8ed3a
https://doi.org/10.1016/s0040-4039(99)02289-3
https://doi.org/10.1016/s0040-4039(99)02289-3