Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ivan, Chalupa"'
Autor:
Petronela Imreova, Jana Feruszova, Stanislav Kyzek, Kristina Bodnarova, Martina Zduriencikova, Katarina Kozics, Pavel Mucaji, Eliska Galova, Andrea Sevcovicova, Eva Miadokova, Ivan Chalupa
Publikováno v:
Molecules, Vol 22, Iss 1, p 167 (2017)
Hyperforin (HF), a substance that accumulates in the leaves and flowers of Hypericum perforatum L. (St. John’s wort), consists of a phloroglucinol skeleton with lipophilic isoprene chains. HF exhibits several medicinal properties and is mainly used
Externí odkaz:
https://doaj.org/article/cd0d0d62cb78428084a073d45b989d99
Autor:
Katarína Kozics, Kristina Bodnarova, Ivan Chalupa, Jana Feruszová, Petronela Imreova, Stanislav Kyzek, Pavel Mučaji, Andrea Sevcovicova, Martina Zduriencikova, Eva Miadoková, Eliška Gálová
Publikováno v:
Molecules; Volume 22; Issue 1; Pages: 167
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules, Vol 22, Iss 1, p 167 (2017)
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules, Vol 22, Iss 1, p 167 (2017)
Hyperforin (HF), a substance that accumulates in the leaves and flowers of Hypericum perforatum L. (St. John’s wort), consists of a phloroglucinol skeleton with lipophilic isoprene chains. HF exhibits several medicinal properties and is mainly used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c46d007ae2836762eaf88017327982ab
Publikováno v:
Military Medical Science Letters. 82:180-184
Summary Hyperforin is a prenylated phloroglucinol derivative which occurs in the plant Hypericum perforatum L. It has several medicinally important properties (antidepressant, anti-inflammatory, proapoptotic, antibacterial and antiangiogenic). To ena
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d63e1f20529e0c3c65e4d9d43bea0df8
https://doi.org/10.31482/mmsl.2013.028
https://doi.org/10.31482/mmsl.2013.028
Autor:
Andrea Babelova, Filip Rázga, Alena Gábelová, Monika Mesárošová, Monika Ursinyova, Barbora Buliaková, Michal Šelc, Veronika Némethová, Lívia Sebová, Ivan Chalupa
Publikováno v:
Nanomedicine: Nanotechnology, Biology and Medicine
Iron oxide nanoparticles are one of the most promising types of nanoparticles for biomedical applications, primarily in the context of nanomedicine-based diagnostics and therapy; hence, great attention should be paid to their bio-safety. Here, we inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad23172c78163805e0cc79079bacdb6b
https://pubmed.ncbi.nlm.nih.gov/27593490
https://pubmed.ncbi.nlm.nih.gov/27593490
Autor:
Marcela Kopaskova, Lubica Alfoldiova, Patricia Gasperova, Daniel Vlček, Eva Miadoková, Zuzana Csanyiova, Eva Čellárová, Andrea Sevcovicova, Eliška Gálová, Ivan Chalupa, Monika Komjatiova, Slavomira Nadova, Alena Hercegova, Viera Vlčková
Publikováno v:
Phytotherapy Research. 24:90-95
The potential genotoxicity and antigenotoxicity of non-photoactivated hypericin was investigated in five experimental models. Hypericin was non-mutagenic in the Ames assay, with and without metabolic activation. It did not exert a protective effect a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b160dea1df773a7a3aa2a88acf3a55bd
https://doi.org/10.1002/ptr.2901
https://doi.org/10.1002/ptr.2901
Autor:
Ivan Chalupa, Eliška Gálová, Jana Feruszová, Eva Miadoková, Stanislav Kyzek, Andrea Sevcovicova, Petronela Imreova, Kristina Bodnarova
Publikováno v:
General physiology and biophysics. 35(2)
The study was designed to test the potential photogenotoxicity of hypericin (HYP) at three different levels: primary DNA damages, gene mutations and chromosome aberrations. Primary genetic changes were detected using the comet assay. The potential mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed760e76d096f6f58ed6d2217b94f437
https://pubmed.ncbi.nlm.nih.gov/26891274
https://pubmed.ncbi.nlm.nih.gov/26891274
Publikováno v:
International Journal of Radiation Biology. 81:177-185
The aim was to investigate whether there are differences in the spontaneous and gamma-ray-induced genomic instability in peripheral blood lymphocytes between untreated cervical cancer patients and healthy women using the sister chromatid exchange (SC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37d7afa9ed67dac8928f9cae79fc261b
https://doi.org/10.1080/09553000500077120
https://doi.org/10.1080/09553000500077120
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 565:105-112
Multifunctional effects of flavonoids are reported to be markedly connected with their structure and the functional groups in the molecule. The important role in the activity play C2-C3 double bond, hydroxyl group at C3 and the number of hydroxyl gro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4b1c517238094b7b25295464bb9ef1e
https://doi.org/10.1016/j.mrgentox.2004.08.013
https://doi.org/10.1016/j.mrgentox.2004.08.013
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 560:91-99
Introduction: N -Nitrosomorpholine (NMOR), present in the workplace of tyre chemical factories, is a known hepatocarcinogen. This compound belongs to the group of N -nitrosamines, which are indirect-acting and require metabolic activation. However, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::113f5e6ca3203d702735889c8bf34af2
https://doi.org/10.1016/j.mrgentox.2004.01.011
https://doi.org/10.1016/j.mrgentox.2004.01.011
Autor:
Jana Tulinska, Mira Horvathova, Aurelia Liskova, Ivan Chalupa, Andrea Sovcikova, Miroslava Kuricova, Katarína Horáková, Zuzana Seemannova
Publikováno v:
International Immunopharmacology. 2:1681-1691
Isothiocyanates (ITCs) have been isolated from plants. Naturally occurring and synthetic ITCs are known as effective chemopreventive agents. Ethyl 4-isothiocyanatobutanoate (E-41B) is a derivative of gamma-aminobutyric acid. Immunotoxic and canoceros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58478abb42e4fd2567db743f03ceba2b
https://doi.org/10.1016/s1567-5769(02)00164-9
https://doi.org/10.1016/s1567-5769(02)00164-9