Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Iva Ugrinova"'
Autor:
Alexander Tzintzarov, Stanislava S. Boyadzhieva, Jose A. P. Coelho, Flora Tsvetanova, Maria Petrova, Georgi Stoev, Dragomir S. Yankov, Iva Ugrinova, Roumiana P. Stateva
Publikováno v:
Molecules, Vol 29, Iss 17, p 4161 (2024)
Sangre de drago, the sap of Croton lechleri Müll. Arg. tree, has been used for centuries in traditional medicine owing to its diverse biological activities. Extracts derived from different parts of the species contain a multitude of phytochemicals w
Externí odkaz:
https://doaj.org/article/aae3618779124054bd1a1d0b9dc9f0b6
Autor:
Alexander Dushkov, Zuzana Vosáhlová, Alexander Tzintzarov, Květa Kalíková, Tomáš Křížek, Iva Ugrinova
Publikováno v:
Molecules, Vol 28, Iss 19, p 6824 (2023)
The fungus Amanita muscaria is universally recognizable for its iconic appearance; it is also widely regarded as poisonous, inedible, and even deadly. In spite of that, there have been documented cases of use of A. muscaria-containing preparations ag
Externí odkaz:
https://doaj.org/article/dd49214e8e634d2fade31201bbbe87fe
Publikováno v:
Mathematics, Vol 11, Iss 10, p 2238 (2023)
Bulgaria has the lowest COVID-19 vaccination rate in the European Union and the second-highest COVID-19 mortality rate in the world. That is why we think it is important better to understand the reason for this situation and to analyse the developmen
Externí odkaz:
https://doaj.org/article/410d2ff7793f4214b80a2110b57f7569
Publikováno v:
Biotechnology & Biotechnological Equipment, Vol 35, Iss 1, Pp 873-879 (2021)
In the recent years, the application of new antitumor drugs has focused on the replacement of conventional chemotherapeutics with compounds derived from natural products. Cannabidiol (CBD) is one of the 113 cannabinoids derived from the plant Cannabi
Externí odkaz:
https://doaj.org/article/95db5563d5614501989152dbf0c39928
Autor:
Maria Schröder, Maria Petrova, Georgi M. Dobrikov, Georgy Grancharov, Denitsa Momekova, Petar D. Petrov, Iva Ugrinova
Publikováno v:
Pharmaceutics, Vol 15, Iss 3, p 791 (2023)
The discovery of new anticancer drugs with а higher, more specific activity and diminished side effects than the conventional chemotherapeutic agents is a tremendous challenge to contemporary medical research and development. To achieve a pronounced
Externí odkaz:
https://doaj.org/article/262cfa7c7cf64137b0dd1ba4daf23c67
Autor:
Maria Petrova, Zlatina Vlahova, Maria Schröder, Jordana Todorova, Alexander Tzintzarov, Anastas Gospodinov, Lyudmila Velkova, Dimitar Kaynarov, Aleksandar Dolashki, Pavlina Dolashka, Iva Ugrinova
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 181 (2023)
This study is the first report describing the promising antitumor activity of biologically active compounds isolated from the hemolymph of marine snail Rapana venosa—a fraction with Mw between 50 and 100 kDa and two structural subunits (RvH1 and Rv
Externí odkaz:
https://doaj.org/article/ecb221d2fd604f368bce376bdbf70504
Publikováno v:
Biotechnology & Biotechnological Equipment, Vol 33, Iss 1, Pp 645-650 (2019)
p53 is usually regarded as a tumour suppressor protein but its constant activation may result in pro-tumorigenic inflammation. The activation of p53 can be provoked by an increase in its concentration as a result of high level transcription, by trans
Externí odkaz:
https://doaj.org/article/21190274a52941bbb2dc3102d0b322a6
Publikováno v:
Mathematics, Vol 10, Iss 15, p 2570 (2022)
Data from the World Health Organization indicate that Bulgaria has the second-highest COVID-19 mortality rate in the world and the lowest vaccination rate in the European Union. In this context, to find the crucial epidemiological parameters that cha
Externí odkaz:
https://doaj.org/article/f0e62472e2fe4a38853ece5a46d8320d
Autor:
Maria Schröder, Maria Petrova, Zlatina Vlahova, Georgi M. Dobrikov, Ivaylo Slavchev, Evdokia Pasheva, Iva Ugrinova
Publikováno v:
Biomedicines, Vol 10, Iss 6, p 1353 (2022)
The successful design of antitumour drugs often combines in one molecule different biologically active subunits that can affect various regulatory pathways in the cell and thus achieve higher efficacy. Two ferrocene derivatives, DK-164 and CC-78, wit
Externí odkaz:
https://doaj.org/article/dd61c85736e648348b1d16e1a100b390
Autor:
Radostina Kalinova, Miroslava Valchanova, Ivaylo Dimitrov, Sevdalina Turmanova, Iva Ugrinova, Maria Petrova, Zlatina Vlahova, Stanislav Rangelov
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 17, p 9606 (2021)
Gene therapy is an attractive therapeutic method for the treatment of genetic disorders for which the efficient delivery of nucleic acids into a target cell is critical. The present study is aimed at evaluating the potential of copolymers based on li
Externí odkaz:
https://doaj.org/article/5f77a52280d04abf94abc3484d514924