Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Iva Pritisanac"'
Autor:
Yu-Xi Xiao, Seon Yong Lee, Magali Aguilera-Uribe, Reuben Samson, Aaron Au, Yukti Khanna, Zetao Liu, Ran Cheng, Kamaldeep Aulakh, Jiarun Wei, Adrian Granda Farias, Taylor Reilly, Saba Birkadze, Andrea Habsid, Kevin R. Brown, Katherine Chan, Patricia Mero, Jie Qi Huang, Maximilian Billmann, Mahfuzur Rahman, Chad Myers, Brenda J. Andrews, Ji-Young Youn, Christopher M. Yip, Daniela Rotin, W. Brent Derry, Julie D. Forman-Kay, Alan M. Moses, Iva Pritišanac, Anne-Claude Gingras, Jason Moffat
Publikováno v:
Cell Reports, Vol 43, Iss 7, Pp 114417- (2024)
Summary: The ability to sense and respond to osmotic fluctuations is critical for the maintenance of cellular integrity. We used gene co-essentiality analysis to identify an unappreciated relationship between TSC22D2, WNK1, and NRBP1 in regulating ce
Externí odkaz:
https://doaj.org/article/6cfa9d4fad5f4dfe962cefa4d0b2f79f
Autor:
Doruntina Bresilla, Hansjoerg Habisch, Iva Pritišanac, Kim Zarse, Warisara Parichatikanond, Michael Ristow, Tobias Madl, Corina T. Madreiter-Sokolowski
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Due to intact reactive oxygen species homeostasis and glucose metabolism, C57BL/6NRj mice are especially suitable to study cellular alterations in metabolism. We applied Nuclear Magnetic resonance spectroscopy to analyze five different tissu
Externí odkaz:
https://doaj.org/article/7444a2211d2f43c883a78096d298a36a
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 6, p e1010238 (2022)
A major challenge to the characterization of intrinsically disordered regions (IDRs), which are widespread in the proteome, but relatively poorly understood, is the identification of molecular features that mediate functions of these regions, such as
Externí odkaz:
https://doaj.org/article/cb97a63ed41d4fd2a040177bf0b5297a
Publikováno v:
eLife, Vol 10 (2021)
In previous work, we showed that intrinsically disordered regions (IDRs) of proteins contain sequence-distributed molecular features that are conserved over evolution, despite little sequence similarity that can be detected in alignments (Zarin et al
Externí odkaz:
https://doaj.org/article/a6e4dce7bd0e4410a47cefd1282bcbdc
Publikováno v:
Entropy, Vol 21, Iss 7, p 662 (2019)
Bioinformatics and biophysical studies of intrinsically disordered proteins and regions (IDRs) note the high entropy at individual sequence positions and in conformations sampled in solution. This prevents application of the canonical sequence-struct
Externí odkaz:
https://doaj.org/article/0c33bbf4540c4c78991b08e2ddcbad8d
Algorithms for computational protein design usually begin with a 3D structure and design an amino acid sequence that will fold into that structure. Since intrinsically disordered protein regions lack stable 3D structures, strategies for their design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::590d54c42aac705f74588963f59cdb52
https://doi.org/10.1101/2023.04.28.538739
https://doi.org/10.1101/2023.04.28.538739
Autor:
Erin E. Duffy, Benjamin Finander, GiHun Choi, Ava C. Carter, Iva Pritisanac, Aqsa Alam, Victor Luria, Amir Karger, William Phu, Maxwell A. Sherman, Elena G. Assad, Naomi Pajarillo, Alexandra Khitun, Elizabeth E. Crouch, Sanika Ganesh, Jin Chen, Bonnie Berger, Nenad Sestan, Anne O’Donnell-Luria, Eric J. Huang, Eric C. Griffith, Julie D. Forman-Kay, Alan M. Moses, Brian T. Kalish, Michael E. Greenberg
Publikováno v:
Nature neuroscience, vol 25, iss 10
The precise regulation of gene expression is fundamental to neurodevelopment, plasticity and cognitive function. Although several studies have profiled transcription in the developing human brain, there is a gap in understanding of accompanying trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51f1812dea783a335dcb51a8256cbbf1
https://escholarship.org/uc/item/6gc2q79k
https://escholarship.org/uc/item/6gc2q79k
Autor:
Bálint Mészáros, András Hatos, Nicolas Palopoli, Federica Quaglia, Edoardo Salladini, Kim Van Roey, Haribabu Arthanari, Zsuzsanna Dosztányi, Isabella C. Felli, Patrick D Fischer, Jeffrey C. Hoch, Cy M Jeffries, Sonia Longhi, Emiliano Maiani, Sandra Orchard, Rita Pancsa, Elena Papaleo, Roberta Pierattelli, Damiano Piovesan, Iva Pritisanac, Thibault Viennet, Peter Tompa, Wim Vranken, Silvio CE Tosatto, Norman E Davey
An unambiguous description of an experimental setup and analysis, and the subsequent biological observation is vital for accurate data interpretation and reproducible results. Consequently, experimental analyses should be described in a concise, uneq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21f49f4a10a13805abedf2e351f974a8
https://doi.org/10.1101/2022.07.12.495092
https://doi.org/10.1101/2022.07.12.495092
Autor:
Emil Spreitzer, T. Reid Alderson, Benjamin Bourgeois, Loretta Eggenreich, Hermann Habacher, Greta Bramerdorfer, Iva Pritišanac, Pedro A. Sánchez-Murcia, Tobias Madl
Publikováno v:
Current Research in Structural Biology, Vol 4, Iss , Pp 118-133 (2022)
Transcription factors play key roles in orchestrating a plethora of cellular mechanisms and controlling cellular homeostasis. Transcription factors share distinct DNA binding domains, which allows to group them into protein families. Among them, the
Externí odkaz:
https://doaj.org/article/7f409bd87d6e4290a919dff475fc1900
Autor:
Livia O. Loureiro, Jennifer L. Howe, Miriam S. Reuter, Alana Iaboni, Kristina Calli, Delnaz Roshandel, Iva Pritišanac, Alan Moses, Julie D. Forman-Kay, Brett Trost, Mehdi Zarrei, Olivia Rennie, Lynette Y. S. Lau, Christian R. Marshall, Siddharth Srivastava, Brianna Godlewski, Elizabeth D. Buttermore, Mustafa Sahin, Dean Hartley, Thomas Frazier, Jacob Vorstman, Stelios Georgiades, Suzanne M. E. Lewis, Peter Szatmari, Clarrisa A. (Lisa) Bradley, Anne-Claude Tabet, Marjolaine Willems, Serge Lumbroso, Amélie Piton, James Lespinasse, Richard Delorme, Thomas Bourgeron, Evdokia Anagnostou, Stephen W. Scherer
Publikováno v:
npj Genomic Medicine, Vol 6, Iss 1, Pp 1-12 (2021)
Abstract Autism Spectrum Disorder (ASD) is genetically complex with ~100 copy number variants and genes involved. To try to establish more definitive genotype and phenotype correlations in ASD, we searched genome sequence data, and the literature, fo
Externí odkaz:
https://doaj.org/article/54f8fe923ab549de9877b0baef9d1c16