Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Iva Klarica Domjanović"'
Autor:
Tamara Božina, Lana Ganoci, Ena Karačić, Livija Šimičević, Majda Vrkić-Kirhmajer, Iva Klarica-Domjanović, Tena Križ, Zrinka Sertić, Nada Božina
Publikováno v:
Annals of Human Biology, Vol 49, Iss 7-8, Pp 323-331 (2022)
Background Organic anion-transporting polypeptide 1B1 (OATP1B1) and the ATP-binding cassette subfamily G member 2, ABCG2, are important transporters involved in the transport of endogenous substrates and xenobiotics, including drugs. Genetic polymorp
Externí odkaz:
https://doaj.org/article/ba302c8799c148b68bd254980828ad93
Autor:
Ivana Šušak Sporiš, Nada Božina, Iva Klarica Domjanović, Davor Sporiš, Silvio Bašić, Ivana Marković, Mila Lovrić, Lana Ganoci, Vladimir Trkulja
To test the hypothesis that the effect of valproate on dose-adjusted lamotrigine troughs was moderated by the ABCG2 c.421C>A (rs2231142) polymorphism, we conducted two studies in adults with epilepsy. Since Study 2 replicated the findings of Study 1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a77ba0b07d64c9774d379d2eeabbcb6b
https://doi.org/10.22541/au.167146513.36768419/v1
https://doi.org/10.22541/au.167146513.36768419/v1
Autor:
Nada Božina, Ivana Šušak Sporiš, Iva Klarica Domjanović, Lana Ganoci, Livija Šimičević, Mila Lovrić, Zrinka Čolak Romić, Željka Petelin Gadže, Vladimir Trkulja
Purpose. To estimate whether epilepsy patients with variant UGT2B7 -161C>T(rs7668258) or UGT1A4*3 c.142T>G(rs2011425) alleles differ from their wild-type (wt) peers in exposure to lamotrigine. Methods. Consecutive adults on lamotrigine monotherapy or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7efc13c7e0c0437f2bca44b09af56a22
https://doi.org/10.21203/rs.3.rs-2297781/v1
https://doi.org/10.21203/rs.3.rs-2297781/v1
Autor:
Tamara Božina, Katarina Gvozdanović, Margareta Fistrek Prlic, Tena Križ, Ana Borić Bilušić, Mario Laganović, Iva Klarica Domjanović, Nada Božina, Livija Šimičević, Lana Ganoci
Publikováno v:
Archives of Industrial Hygiene and Toxicology
Concomitant treatment with drugs that inhibit drug metabolising enzymes and/or transporters, such as commonly prescribed statins and nonsteroidal anti-inflammatory drugs (NSAIDs), has been associated with prolonged drug exposure and increased risk of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6017d5c54a4f60d1106907d5e2d32fed
https://doi.org/10.2478/aiht-2021-72-3549
https://doi.org/10.2478/aiht-2021-72-3549
Autor:
Nada Božina, Lana Ganoci, Livija Simičević, Katarina Gvozdanović, Iva Klarica Domjanović, Margareta Fistrek Prlić, Tena Križ, Ana Borić Bilušić, Mario Laganović, Tamara Božina
Publikováno v:
Arhiv za higijenu rada i toksikologiju
Volume 72
Issue 2
Volume 72
Issue 2
Statini i nesteroidni protuupalni lijekovi (NSAID) učestalo se propisuju, pa i kao konkomitantna terapija. Postoji značajna interindividualna razlika u osjetljivosti na njihove najčešće nuspojave. Rizični čimbenici za razvoj nuspojava tih lije
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______951::ee520fd955d9f0c1415d0e7565383620
https://hrcak.srce.hr/258902
https://hrcak.srce.hr/258902
Autor:
Mila Lovrić, Željka Petelin-Gadže, Nada Božina, Iva Klarica Domjanović, Ivana Čajić, Vladimir Trkulja, Lana Ganoci
Publikováno v:
British Journal of Clinical Pharmacology. 84:2106-2119
AIMS To investigate the impact of glucuronidation enzyme (UGT1A4*3 142T>G, UGT1A4*2 70C>A, UGT2B7 -161C>T) and transporter (MDR1/ABCB1 1236C>T, ABCG2 421C>A) polymorphisms on steady-state disposition of lamotrigine and on the lamotrigine-valproate in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2317c490d65abee93407d508ecbe73e4
https://doi.org/10.1111/bcp.13646
https://doi.org/10.1111/bcp.13646
Autor:
Nada Božina, Tamara Božina, Davor Sporiš, Ante Tvrdeić, Iva Klarica-Domjanović, Ivana Šušak Sporiš
Seizure control with antiepileptic drugs (AEDs) as well as susceptibility to adverse drug reactions varies among individuals with epilepsy. This interindividual variability is partly determined by genetic factors. However, genetic testing to predict
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b26ed257ba83d9b7f3e5167f5084b5d1
https://doi.org/10.2217/pgs-2019-0085
https://doi.org/10.2217/pgs-2019-0085
Publikováno v:
Archives of Industrial Hygiene and Toxicology. 67:1-8
Interindividual variability in drug metabolism is an important cause of adverse drug reactions and variability in drug efficiency. Polymorphisms of cytochrome P450 (CYPs) genes have a significant effect on drug metabolism and toxicity. This review br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cc4164e8a45627c91b637436b1ebaf9
https://doi.org/10.1515/aiht-2016-67-2754
https://doi.org/10.1515/aiht-2016-67-2754
Publikováno v:
Croatian Medical Journal
Volume 59
Issue 1
Volume 59
Issue 1
AIM: To estimate the effect size of concomitant antiepileptic therapy on the concentrations of lamotrigine, a drug often prescribed in combination with other antiepileptic drugs (AED), which can act as enzyme inducers or inhibitors. ----- METHODS: A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::060b017d4bb9803b142d4ac79ad5c519
https://www.bib.irb.hr/930004
https://www.bib.irb.hr/930004
Publikováno v:
Arhiv za higijenu rada i toksikologiju
Volume 67
Issue 1
Volume 67
Issue 1
Interindividual variability in drug metabolism is an important cause of adverse drug reactions and variability in drug efficiency. Polymorphisms of cytochrome P450 (CYPs) genes have a significant effect on drug metabolism and toxicity. This review br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______951::b06f9902b4262d402740eea6ad6e2c88
https://hrcak.srce.hr/file/227797
https://hrcak.srce.hr/file/227797