Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Iva Kejnovská"'
Publikováno v:
Mobile DNA, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Background Canonical telomeres (telomerase-synthetised) are readily forming G-quadruplexes (G4) on the G-rich strand. However, there are examples of non-canonical telomeres among eukaryotes where telomeric tandem repeats are invaded by speci
Externí odkaz:
https://doaj.org/article/8b86b1add91b4f9f86f01b1b38bbe7e7
Autor:
Lucia Hároníková, Jan Coufal, Iva Kejnovská, Eva B Jagelská, Miroslav Fojta, Petra Dvořáková, Petr Muller, Borivoj Vojtesek, Václav Brázda
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157156 (2016)
Interferon-inducible protein 16 (IFI16) is a member of the HIN-200 protein family, containing two HIN domains and one PYRIN domain. IFI16 acts as a sensor of viral and bacterial DNA and is important for innate immune responses. IFI16 binds DNA and bi
Externí odkaz:
https://doaj.org/article/907c38be29d3427da9f41e3e10e8435d
Autor:
Jan Palacký, Petr Stadlbauer, Iva Kejnovská, Martin Gajarský, Lukáš Trantírek, Jean-Louis Mergny, Daniel Krafčík, Jiří Šponer, Daniel Renčiuk, Klára Bednářová, Michaela Vorlíčková
Publikováno v:
Chemistry – A European Journal. 27:12115-12125
Guanine quadruplexes (G4s) are noncanonical forms of nucleic acids that are frequently found in genomes. The stability of G4s depends, among other factors, on the number of G-tetrads. Three- or four-tetrad G4s and antiparallel two-tetrad G4s have bee
Variation in G-quadruplex Sequence and Topology Differentially Impacts Human DNA Polymerase Fidelity
Autor:
MaryElizabeth Stein, Suzanne E. Hile, Matthias H. Weissensteiner, Marietta Lee, Sufang Zhang, Eduard Kejnovský, Iva Kejnovská, Kateryna D. Makova, Kristin A. Eckert
Publikováno v:
DNA Repair (Amst)
G-quadruplexes (G4s), a type of non-B DNA, play important roles in a wide range of molecular processes, including replication, transcription, and translation. Genome integrity relies on efficient and accurate DNA synthesis, and is compromised by vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54a3d1669381473755166e400d871c4e
https://europepmc.org/articles/PMC9798401/
https://europepmc.org/articles/PMC9798401/
Publikováno v:
Journal of Raman Spectroscopy. 51:301-312
Autor:
Michaela Vorlíčková, Zuzana Dvorakova, Hana Pivonkova, Iva Kejnovská, Iveta Triskova, Libuše Trnková, Radovan Fiala
Publikováno v:
Electroanalysis. 31:2081-2093
The paper shows the structural diversity of cytosine (C)-rich oligodeoxynucleotides (ODNs) arising from their detail nucleotide sequence and experimental conditions. In slightly acidic solutions, the ODN nonamers with different adenine (A) and cytosi
Autor:
Viktor Tokan, Eduard Kejnovsky, Iva Kejnovská, José Luis Rodríguez Lorenzo, Pavel Jedlička, Roman Hobza
Publikováno v:
Biology, Vol 10, Iss 347, p 347 (2021)
Biology
Volume 10
Issue 4
Biology
Volume 10
Issue 4
Simple Summary Four-stranded DNA (guanine quadruplex) can regulate many cellular processes such as replication, recombination and also gene expression. This study shows that four-stranded DNA can also affect the activity of mobile genetic elements (t
Publikováno v:
Chemistry – A European Journal. 25:13422-13428
Guanine quadruplexes, recently reported to form in vivo, represent a broad spectrum of non-canonical conformations of nucleic acids. The actual conformation might differ between water solutions and crowding or dehydrating solutions that better reflec
Autor:
Michaela Vorlíčková, Iva Kejnovská, Jan Palacký, Daniel Krafčík, Daniel Renčiuk, Petra Školáková, Zuzana Dvořáková, Klára Bednářová
Publikováno v:
Nucleic Acids Research
The formation of intercalated motifs (iMs) — secondary DNA structures based on hemiprotonated C.C+ pairs in suitable cytosine-rich DNA sequences, is reflected by typical changes in CD and UV absorption spectra. By means of spectroscopic methods, el
Autor:
Zuzana Dvorakova, Petra Školáková, Daniel Renčiuk, Iva Kejnovská, Michaela Vorlíčková, Janos Sagi, Klára Bednárová
Publikováno v:
Nucleic Acids Research
i-Motif (iM) is a four stranded DNA structure formed by cytosine-rich sequences, which are often present in functionally important parts of the genome such as promoters of genes and telomeres. Using electronic circular dichroism and UV absorption spe