Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Iva Jelínková"'
Autor:
Iva Vesela, Petr Dvorak, Miroslav Varecha, Vitezslav Bryja, Iveta Cervenkova, Alois Kozubík, Marcela Buchtová, Iva Jelínková, Anie Aklian, Petr Matula, Zaneta Konecna, Tereza Spoustova, Pavel Krejci, Tereza Pospisilova, Ivan Duran, Tereza Obadalova, Lukas Balek, Iva Gudernova, Shunichi Murakami, Veronika Oralova, Jan Masek, Zhufeng Ouyang
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1852:839-850
Aberrant fibroblast growth factor (FGF) signaling disturbs chondrocyte differentiation in skeletal dysplasia, but the mechanisms underlying this process remain unclear. Recently, FGF was found to activate canonical WNT/β-catenin pathway in chondrocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14465e4e13778bc39cc17e42b09e648c
https://doi.org/10.1016/j.bbadis.2014.12.020
https://doi.org/10.1016/j.bbadis.2014.12.020
Author response: One reporter for in-cell activity profiling of majority of protein kinase oncogenes
Autor:
Bohumil Fafilek, Jiri Mayer, Pavel Krejci, Iva Jelínková, Miroslav Varecha, Silvie Foldynová-Trantírková, Eva Hrubá, Barbora El Ghannamova, Michaela Bosakova, Lucie Jonatova, Lukas Balek, Iva Gudernova, Lukáš Trantírek
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f2b23ff3e943ae2e39fdf833ea9c522
https://doi.org/10.7554/elife.21536.024
https://doi.org/10.7554/elife.21536.024
Autor:
Miroslav Machala, Alena Hyršlová Vaculová, Iva Jelínková, Mary Pat Moyer, Jiřina Hofmanová, Alois Kozubík, Josef Slavík, Belma Skender
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1841:1308-1317
Docosahexaenoic acid (DHA), an n-3 polyunsaturated fatty acid present in fish oil, may exert cytotoxic and/or cytostatic effects on colon cancer cells when applied individually or in combination with some anticancer drugs. Here we demonstrate a selec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56a75144a9d4009a2a1e34c6fa5cdf53
https://doi.org/10.1016/j.bbalip.2014.06.005
https://doi.org/10.1016/j.bbalip.2014.06.005
Autor:
Jiřina Hofmanová, Iva Jelínková, Alois Kozubík, A. Hyršlová Vaculová, Petr Sova, O. Vondálová Blanářová
Publikováno v:
Cell Proliferation. 46:665-676
OBJECTIVES: Therapeutic potential of conventionally used platinum‐based drugs in treatment of colorectal tumours has been limited due to high incidence of tumour resistance to them and to their severe side effects. This evokes a search for more sui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93c6858ecb4c096e786c49dccc3610e7
https://doi.org/10.1111/cpr.12061
https://doi.org/10.1111/cpr.12061
Autor:
Jieun Song, Margie Jaworski, Deborah Krakow, Lukas Balek, Michael J. Bamshad, Michaela Bosakova, S. Paige Taylor, Iva Jelínková, Miroslav Varecha, Aleš Hampl, Pavel Krejci, Ivan Duran, Jorge H. Martin, Kimberly N. Forlenza, Iva Vesela, Lukáš Trantírek, Daniel H. Cohn, Tomáš Bárta, Hyuk Wan Ko, Deborah A. Nickerson
Publikováno v:
Human molecular genetics. 25(18)
The short rib polydactyly syndromes (SRPS) are a group of recessively inherited, perinatal-lethal skeletal disorders primarily characterized by short ribs, shortened long bones, varying types of polydactyly and concomitant visceral abnormalities. Mut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4138356c0e38618bf901a4070652c0a4
https://pubmed.ncbi.nlm.nih.gov/27466187
https://pubmed.ncbi.nlm.nih.gov/27466187
Autor:
János Szöllősi, Viktor Horváth, Jiřina Hofmanová, Alois Kozubík, Ladislav Anděra, Alena Hyršlová Vaculová, György Vereb, Petr Sova, Olga Vondálová Blanářová, Karel Souček, Árpád Szöőr, Belma Skender, Iva Jelínková
Publikováno v:
Carcinogenesis. 32:42-51
TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) can selectively trigger apoptosis in various cancer cell types. However, many cancer cells are resistant to death receptor-mediated apoptosis. Combination therapy with platinum complexes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc9772ac1b9e185905d52b996ed6aa3f
https://doi.org/10.1093/carcin/bgq220
https://doi.org/10.1093/carcin/bgq220
Autor:
Jakub Pivnicka, Alois Kozubík, Lucie Roubalova, Michaela Kunová, Iva Vesela, Hana Dosedelova, Iva Gudernova, Lukas Balek, Marcela Buchtová, Pavel Krejci, Iva Jelínková
Publikováno v:
Human molecular genetics. 25(1)
Activating mutations in the fibroblast growth factor receptor 3 (FGFR3) cause the most common genetic form of human dwarfism, achondroplasia (ACH). Small chemical inhibitors of FGFR tyrosine kinase activity are considered to be viable option for trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::752881abdfe46775ec4ebcc3ac2a3d3a
https://pubmed.ncbi.nlm.nih.gov/26494904
https://pubmed.ncbi.nlm.nih.gov/26494904
Autor:
Etienne van Bracht, Dorien Reijnders, Alf Grandien, Alena Vaculova, Barbora Safarikova, Birce Akpinar, Magnus Olsson, Boris Zhivotovsky, Iva Jelínková
Publikováno v:
Oncotarget
// Birce Akpinar 1 , Ethiene V. Bracht 1 , Dorin Reijnders 1 , Barbora Safarikova 2 , Iva Jelinkova 2 , Alf Grandien 3 , Alena Hyrslova Vaculova 1, 2 , Boris Zhivotovsky 1 , Magnus Olsson 1 1 Division of Toxicology, Institute of Environmental Medicin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53dbe7f9222301e4cc148ee9b9699458
https://pubmed.ncbi.nlm.nih.gov/28053293
https://pubmed.ncbi.nlm.nih.gov/28053293
Autor:
Mary Pat Moyer, Zdeněk Kolář, Belma Skender, Jiří Ehrmann, Iva Jelínková, Petr Sova, Alena Hyršlová Vaculová, Barbora Šafaříková, Alois Kozubík, Olga Vondálová Blanářová, Jiřina Hofmanová
Publikováno v:
Biochemical pharmacology. 92(3)
In search for novel strategies in colon cancer treatment, we investigated the unique ability of platinum(IV) complex LA-12 to efficiently enhance the killing effects of tumor necrosis factor-related apoptosis inducing ligand (TRAIL), and compared it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d676a711de8f34bc08ce3ee2979f0ee5
https://pubmed.ncbi.nlm.nih.gov/25285768
https://pubmed.ncbi.nlm.nih.gov/25285768
Autor:
Josef Slavík, Jan Svadlenka, Nada Hradilova, Jan Brazina, Martin Klima, Alena Hyršlová Vaculová, Michal Koc, Ladislav Andera, Vladimira Horova, Iva Jelínková
Publikováno v:
The FEBS journal. 280(14)
Tumour necrosis factor (TNF) related apoptosis inducing ligand (TRAIL), a membrane-bound ligand from the TNF family, has attracted significant attention due to its rather specific and effective ability to induce apoptotic death in various types of ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a68ea97b37198b8e670d4eb996c0566
https://pubmed.ncbi.nlm.nih.gov/23678861
https://pubmed.ncbi.nlm.nih.gov/23678861