Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Iva Hafner-Bratkovic"'
Autor:
Magdalini Polymenidou, Rita Moos, Mike Scott, Christina Sigurdson, Yong-Zhong Shi, Bill Yajima, Iva Hafner-Bratkovic, Roman Jerala, Simone Hornemann, Kurt Wuthrich, Anne Bellon, Martin Vey, Graciela Garen, Michael N G James, Nat Kav, Adriano Aguzzi
Publikováno v:
PLoS ONE, Vol 3, Iss 12, p e3872 (2008)
PrP(Sc), a misfolded and aggregated form of the cellular prion protein PrP(C), is the only defined constituent of the transmissible agent causing prion diseases. Expression of PrP(C) in the host organism is necessary for prion replication and for pri
Externí odkaz:
https://doaj.org/article/729d5a629adc4e109df2f2dba9164797
Publikováno v:
FEBS lettersReferences. 594(15)
The considerable potential of engineered cells compels the development of strategies for the stringent control of gene expression. A promising approach is the introduction of a premature stop codon (PTC) into a selected gene that is expressed only in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9e41e9581064d33f6af6e1727bf5d4d
https://pubmed.ncbi.nlm.nih.gov/32401336
https://pubmed.ncbi.nlm.nih.gov/32401336
Autor:
Duško Lainšček, Lucija Kadunc, Iva Hafner Bratkovic, Rok Romih, Mateja Manček Keber, Roman Jerala
Publikováno v:
ACS synthetic biology. 7(12)
The CRISPR/Cas system has been developed as a potent tool for genome engineering and transcription regulation. However, the efficiency of the delivery of the system into cells, particularly for therapeutic in vivo applications, remains a major bottle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac057486b6951d2d86fd38fccd218170
https://pubmed.ncbi.nlm.nih.gov/30513193
https://pubmed.ncbi.nlm.nih.gov/30513193
Publikováno v:
The Journal of Immunology. 206:111.06-111.06
Cleavage of gasdermin D (GSDMD) by inflammatory caspases results in pore formation at the plasma membrane. GSDMD pores are recognized to mediate pyroptotic lysis of the cell or direct translocation of IL-1 family cytokines from the cytosol into the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4238dda82bf6f490f3c9de26e0f441ff
https://doi.org/10.4049/jimmunol.206.supp.111.06
https://doi.org/10.4049/jimmunol.206.supp.111.06
Publikováno v:
The Journal of Immunology. 204:149.7-149.7
Cleavage of gasdermin D (GSDMD) by inflammatory caspases results in pore formation at the plasma membrane. GSDMD pores are recognized to mediate pyroptotic lysis of the cell or direct translocation of IL-1 family cytokines from the cytosol into the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef7ec60d6ef2c5c7684eaa2cb2cf9ecb
https://doi.org/10.4049/jimmunol.204.supp.149.7
https://doi.org/10.4049/jimmunol.204.supp.149.7
Autor:
Lucija Kadunc Polajnar, Duško Lainšček, Rok Gašperšič, Petra Sušjan-Leite, Uroš Kovačič, Miha Butinar, Boris Turk, Roman Jerala, Iva Hafner-Bratkovič
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Growth factors are the key regulators that promote tissue regeneration and healing processes. While the effects of individual growth factors are well documented, a combination of multiple secreted growth factors underlies stem cell–mediated regener
Externí odkaz:
https://doaj.org/article/890b6d7be7794493898c0da70997a1ed
Autor:
Pascal Devant, Elvira Boršić, Elsy M. Ngwa, Haopeng Xiao, Edward T. Chouchani, Jay R. Thiagarajah, Iva Hafner-Bratkovič, Charles L. Evavold, Jonathan C. Kagan
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 112008- (2023)
Summary: Reactive oxygen species (ROS) regulate the activities of inflammasomes, which are innate immune signaling organelles that induce pyroptosis. The mechanisms by which ROS control inflammasome activities are unclear and may be multifaceted. Her
Externí odkaz:
https://doaj.org/article/a61895e553eb4a44ae43092e7d90e406
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The pathogenesis of neurodegenerative diseases involves the accumulation of misfolded protein aggregates. These deposits are both directly toxic to neurons, invoking loss of cell connectivity and cell death, and recognized by innate sensors that upon
Externí odkaz:
https://doaj.org/article/efd41a2703b246ce8265f15b24c87370
Autor:
Jernej, Gaspersic, Iva, Hafner-Bratkovic, Michel, Stephan, Peter, Veranic, Mojca, Bencina, Ina, Vorberg, Roman, Jerala
Publikováno v:
The FEBS journal. 277(9)
The conformational conversion of prion protein (PrP) from a native conformation to the amyloid form is a hallmark of transmissible spongiform encephalopathies. Conversion is usually monitored by fluorescent dyes, which bind generic amyloids and are l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::20830473eced2937fb69b896508cf847
https://pubmed.ncbi.nlm.nih.gov/20345906
https://pubmed.ncbi.nlm.nih.gov/20345906
Publikováno v:
Journal of neurochemistry. 104(6)
Conversion of the native, predominantly alpha-helical conformation of prion protein (PrP) into the beta-stranded conformation is characteristic for the transmissible spongiform encephalopathies such as Creutzfeld-Jakob disease. Curcumin, an extended
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6f473cb74e1ea866e21e5e7d42cb8af2
https://pubmed.ncbi.nlm.nih.gov/17996023
https://pubmed.ncbi.nlm.nih.gov/17996023