Zobrazeno 1 - 10 of 33 pro vyhledávání: '"Iván V Rosado"'
1
Akademický článek
The Fanconi Anemia Pathway Protects Genome Integrity from R-loops.
Autor: María L García-Rubio, Carmen Pérez-Calero, Sonia I Barroso, Emanuela Tumini, Emilia Herrera-Moyano, Iván V Rosado, Andrés Aguilera
Publikováno v: PLoS Genetics, Vol 11, Iss 11, p e1005674 (2015)
Co-transcriptional RNA-DNA hybrids (R loops) cause genome instability. To prevent harmful R loop accumulation, cells have evolved specific eukaryotic factors, one being the BRCA2 double-strand break repair protein. As BRCA2 also protects stalled repl
Externí odkaz: https://doaj.org/article/f837cc8569b3404c8b6b85ce1a4f0b64
Zobrazit plný text záznamu
2
Akademický článek
Final pre-40S maturation depends on the functional integrity of the 60S subunit ribosomal protein L3.
Autor: Juan J García-Gómez, Antonio Fernández-Pevida, Simon Lebaron, Iván V Rosado, David Tollervey, Dieter Kressler, Jesús de la Cruz
Publikováno v: PLoS Genetics, Vol 10, Iss 3, p e1004205 (2014)
Ribosomal protein L3 is an evolutionarily conserved protein that participates in the assembly of early pre-60S particles. We report that the rpl3[W255C] allele, which affects the affinity and function of translation elongation factors, impairs cytopl
Externí odkaz: https://doaj.org/article/b3841e69e48a43889a4d0513b046d6fd
Zobrazit plný text záznamu
3
Akademický článek
FANCD2 maintains replication fork stability during misincorporation of the DNA demethylation products 5-hydroxymethyl-2’-deoxycytidine and 5-hydroxymethyl-2’-deoxyuridine
Autor: María José Peña-Gómez, Paula Moreno-Gordillo, Milda Narmontė, Clara B. García-Calderón, Audronė Rukšėnaitė, Saulius Klimašauskas, Iván V. Rosado
Publikováno v: Cell Death and Disease, Vol 13, Iss 5, Pp 1-11 (2022)
Abstract Fanconi anemia (FA) is a rare hereditary disorder caused by mutations in any one of the FANC genes. FA cells are mainly characterized by extreme hypersensitivity to interstrand crosslink (ICL) agents. Additionally, the FA proteins play a cru
Externí odkaz: https://doaj.org/article/7fd4ade5ca314852823a480a360e6bc8
Zobrazit plný text záznamu
4
Akademický článek
Metallo-Liposomes of Ruthenium Used as Promising Vectors of Genetic Material
Autor: José Antonio Lebrón, Francisco José Ostos, Manuel López-López, María Luisa Moyá, Carlos Sales, Encarnación García, Clara Beatriz García-Calderón, Margarita García-Calderón, María José Peña-Gómez, Iván V. Rosado, Fernando R. Balestra, Pablo Huertas, Pilar López-Cornejo
Publikováno v: Pharmaceutics, Vol 12, Iss 5, p 482 (2020)
Gene therapy is a therapeutic process consisting of the transport of genetic material into cells. The design and preparation of novel carriers to transport DNA is an important research line in the medical field. Hybrid compounds such as metallo-lipos
Externí odkaz: https://doaj.org/article/9eb3e8cbc36a4db28be60ab9033afbc6
Zobrazit plný text záznamu
5
XRCC1 Prevents Replication Fork Instability during Misincorporation of the DNA Demethylation Bases 5-Hydroxymethyl-2′-Deoxycytidine and 5-Hydroxymethyl-2′-Deoxyuridine
Autor: María José Peña-Gómez, Marina Suárez-Pizarro, Iván V. Rosado
Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 893
idUS. Depósito de Investigación de la Universidad de Sevilla
International Journal of Molecular Sciences, Vol 23, Iss 893, p 893 (2022)
Whilst avoidance of chemical modifications of DNA bases is essential to maintain genome stability, during evolution eukaryotic cells have evolved a chemically reversible modification of the cytosine base. These dynamic methylation and demethylation r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::292c31a2dfdf77674f3cd2d053133cb2
http://hdl.handle.net/10261/283048
Zobrazit plný text záznamu
7
Multivalent Calixarene-Based Liposomes as Platforms for Gene and Drug Delivery
Autor: Manuel López-López, Pablo Huertas, María Luisa Moyá, Eva Bernal, Clara B. García-Calderón, José Antonio Lebrón, Iván V. Rosado, Pilar López-Cornejo, Francisco José Ostos, Fernando R. Balestra, Vitaly I. Kalchenko, Roman V. Rodik
Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
Arias Montano. Repositorio Institucional de la Universidad de Huelva
Pharmaceutics
Pharmaceutics, Vol 13, Iss 1250, p 1250 (2021)
idUS. Depósito de Investigación de la Universidad de Sevilla
Volume 13
Issue 8
The formation of calixarene-based liposomes was investigated, and the characterization of these nanostructures was carried out using several techniques. Four amphiphilic calixarenes were used. The length of the hydrophobic chains attached to the lowe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f542250b7e792026658a384e2a4be99
https://hdl.handle.net/10668/3826
Zobrazit plný text záznamu
8
Metallo-Liposomes Derived from the [Ru(bpy)3]2+ Complex as Nanocarriers of Therapeutic Agents
Autor: Manuel López-López, José Antonio Lebrón, Paula Moreno-Gordillo, Izamar Moreno, Pilar López-Cornejo, María Luisa Moyá, Diandra García, Francisco José Ostos, Iván V. Rosado
Publikováno v: Chemosensors, Vol 9, Iss 90, p 90 (2021)
idUS: Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Digital.CSIC. Repositorio Institucional del CSIC
Chemosensors; Volume 9; Issue 5; Pages: 90
This article belongs to the Special Issue The Application of Nanocarriers in Therapeutic Agents.
The obtaining of nanocarriers of gene material and small drugs is still an interesting research line. Side-effects produced by the toxicity of sever
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b226624b6840021ad00daf0db94bffe
https://www.mdpi.com/2227-9040/9/5/90
Zobrazit plný text záznamu
9
Self-aggregation in aqueous solution of amphiphilic cationic calix[4]arenes. Potential use as vectors and nanocarriers
Autor: Manuel López-López, Vitaly I. Kalchenko, María Luisa Moyá, Iván V. Rosado, Pilar López-Cornejo, Margarita García-Calderón, Clara B. García-Calderón, Francisco José Ostos, José Antonio Lebrón, Roman V. Rodik
Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
The self-aggregation of four amphiphilic cationic calix[4]arenes, CALIX, in aqueous solutions was investigated in this work. The nature of the polar group present at the upper rim as well as the length of the hydrophobic tails attached to the lower r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::920d316d957feaf18e9fca1452e22869
http://hdl.handle.net/10261/236253
Zobrazit plný text záznamu
10
Metallo-Liposomes of Ruthenium Used as Promising Vectors of Genetic Material
Autor: María Luisa Moyá, Encarnación García, Iván V. Rosado, José Antonio Lebrón, Francisco José Ostos, Margarita García-Calderón, Manuel López-López, Pablo Huertas, Pilar López-Cornejo, María José Peña-Gómez, Clara B. García-Calderón, Fernando R. Balestra, Carlos Sales
Publikováno v: idUS: Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Pharmaceutics
Volume 12
Issue 5
Arias Montano. Repositorio Institucional de la Universidad de Huelva
Digital.CSIC. Repositorio Institucional del CSIC
Pharmaceutics, Vol 12, Iss 482, p 482 (2020)
Gene therapy is a therapeutic process consisting of the transport of genetic material into cells. The design and preparation of novel carriers to transport DNA is an important research line in the medical field. Hybrid compounds such as metallo-lipos
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a945d6286abb9443092123a67e99b2c
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje