Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Iván Iglesias-Baena"'
Autor:
María Luisa Alés-Palmer, Francisco Andújar-Vera, Iván Iglesias-Baena, Paloma Muñoz-de-Rueda, Esther Ocete-Hita
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1288 (2024)
Idiosyncratic drug-induced liver injury (DILI) is a complex multifactorial disease in which the toxic potential of the drug, together with genetic and acquired factors and deficiencies in adaptive processes, which limit the extent of damage, may dete
Externí odkaz:
https://doaj.org/article/f30451e6a51a48ceb648db5ca57ba2c1
Autor:
Francisco Andújar-Vera, María Luisa Alés-Palmer, Paloma Muñoz-de-Rueda, Iván Iglesias-Baena, Esther Ocete-Hita
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13562 (2023)
Hepatotoxicity, a common adverse drug effect, has been extensively studied in adult patients. However, it is equally important to investigate this condition in pediatric patients to develop personalized treatment strategies for children. This study a
Externí odkaz:
https://doaj.org/article/d840095ee33c4df5bd63f95ccafa3885
Autor:
Raquel Sanabria-de la Torre, Luis Martínez-Heredia, Sheila González-Salvatierra, Francisco Andújar-Vera, Iván Iglesias-Baena, Juan Miguel Villa-Suárez, Victoria Contreras-Bolívar, Mario Corbacho-Soto, Gonzalo Martínez-Navajas, Pedro J. Real, Cristina García-Fontana, Manuel Muñoz-Torres, Beatriz García-Fontana
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Hypophosphatasia (HPP) a rare disease caused by mutations in the ALPL gene encoding for the tissue-nonspecific alkaline phosphatase protein (TNSALP), has been identified as a potentially under-diagnosed condition worldwide which may have higher preva
Externí odkaz:
https://doaj.org/article/6b8f1fbf88af40f096d6a33378987f4e
Autor:
Francisco Andújar-Vera, Cristina García-Fontana, Raquel Sanabria-de la Torre, Sheila González-Salvatierra, Luis Martínez-Heredia, Iván Iglesias-Baena, Manuel Muñoz-Torres, Beatriz García-Fontana
Publikováno v:
Biomedicines, Vol 10, Iss 2, p 389 (2022)
The identification of common targets in Alzheimer’s disease (AD) and cardiovascular disease (CVD) in recent years makes the study of the CVD/AD axis a research topic of great interest. Besides aging, other links between CVD and AD have been describ
Externí odkaz:
https://doaj.org/article/5e78e24dd9774d8c8c71b7fd3b6541d5
Autor:
Isabel A Calvo, Natalia Gabrielli, Iván Iglesias-Baena, Sarela García-Santamarina, Kwang-Lae Hoe, Dong Uk Kim, Miriam Sansó, Alice Zuin, Pilar Pérez, José Ayté, Elena Hidalgo
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6619 (2009)
BackgroundAn excess of caffeine is cytotoxic to all eukaryotic cell types. We aim to study how cells become tolerant to a toxic dose of this drug, and the relationship between caffeine and oxidative stress pathways.Methodology/principal findingsWe se
Externí odkaz:
https://doaj.org/article/471ade7ebfe54409a0bfa95fab07d3f7
Autor:
Iván Iglesias-Baena, Beatriz García-Fontana, Silvia Lozano-Alonso, Sheila González-Salvatierra, Cristina García-Fontana, Manuel Muñoz-Torres, Francisco Andújar-Vera
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 190:113535
Currently, there are not many in-depth studies focusing on the protein analysis of antioxidants involved in the calcification of the femoral artery. In this context, this study aimed to increase the knowledge of the molecular redox mechanisms involve
Autor:
Aingeru Calderón, Francisca Sevilla, Daymi Camejo, J. J. Lázaro, Iván Iglesias-Baena, Alfonso Lázaro-Payo, Ana I. Jiménez
Publikováno v:
Frontiers in Plant Science
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
Together with thioredoxins (Trxs), plant peroxiredoxins (Prxs), and sulfiredoxins (Srxs) are involved in antioxidant defense and redox signaling, while their regulation by post-translational modifications (PTMs) is increasingly regarded as a key comp
Publikováno v:
Plant Physiology. 155:944-955
Sulfiredoxin (Srx) couples the energy of ATP hydrolysis to the energetically unfavorable process of reducing the inactive sulfinic form of 2-cysteine peroxiredoxins (Prxs) to regenerate its active form. In plants, Srx as well as typical 2-cysteine Pr
Autor:
Sergio Barranco-Medina, Francisco Javier Lopez-Jaramillo, Juan-José Lázaro, Iván Iglesias-Baena, Francisca Sevilla, Alfonso Lázaro-Payo
Publikováno v:
Journal of Experimental Botany
The antioxidant function of 2-Cys peroxiredoxin (Prx) involves the oxidation of its conserved peroxidatic cysteine to sulphenic acid that is recycled by a reductor agent. In conditions of oxidative stress, the peroxidatic cysteine can be overoxidized
Autor:
Ana I. Jiménez, J. J. Lázaro, María C. Martí, Iván Iglesias-Baena, Sergio Barranco-Medina, Francisca Sevilla, Alfonso Lázaro-Payo, Daymi Camejo
Publikováno v:
Frontiers in Plant Science, Vol 4 (2013)
Frontiers in Plant Science
Digital.CSIC. Repositorio Institucional del CSIC
instname
Frontiers in Plant Science
Digital.CSIC. Repositorio Institucional del CSIC
instname
Mitochondrial respiration provides the energy needed to drive metabolic and transport processes in cells. Mitochondria are a significant site of reactive oxygen species (ROS) production in plant cells, and redox-system components obey fine regulation