Estudio de biodisponibilidad relativa entre dos formulaciones orales de micofenolato mofetilo en voluntarios sanos

Autor: Jaime Sasso A, Luis Quiñones S, Jorge Soto L, Iván Saavedra S, Cristóbal Carvajal H, Mónica Saavedra B, Ignacio Boza T, Leonardo Gaete G

Publikováno v: Revista médica de Chile v.139 n.7 2011
SciELO Chile
CONICYT Chile
instacron:CONICYT

Background The bioequivalence of different formulations of a same pharmaceutical product must be tested empirically. Aim To evaluate the relative bioavailability for an oralformulation of mycophenolate mofetil (MMF) (Linfonex™) compared to the refe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a44d519f414b3ae902b96338b7ac006d
https://doi.org/10.4067/s0034-98872011000700011

[Relative bioavailability study of two oral formulations of mycophenolate mofetil in healthy volunteers]

Autor: Iván, Saavedra S, Jaime, Sasso A, Luis, Quiñones S, Mónica, Saavedra B, Leonardo, Gaete G, Ignacio, Boza T, Cristóbal, Carvajal H, Jorge, Soto L

Publikováno v: Revista medica de Chile. 139(7)

The bioequivalence of different formulations of a same pharmaceutical product must be tested empirically.To evaluate the relative bioavailability for an oralformulation of mycophenolate mofetil (MMF) (Linfonex™) compared to the reference formulatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::638e71d93a3b57c85657fb99b79f1649
https://pubmed.ncbi.nlm.nih.gov/22051828

Papel de las enzimas citocromo p450 en el metabolismo de fármacos antineoplásicos: Situación actual y perspectivas terapéuticas

Autor: Nelson Varela F, Jaime Sasso A, Mario Rosero P, Ángela Roco A, Iván Moreno T, Luis Quiñones S, Iván Saavedra S, Dante Cáceres L

Publikováno v: Revista médica de Chile v.136 n.10 2008
SciELO Chile
CONICYT Chile
instacron:CONICYT

Cytochrome P450 enzymes are very important to metabolize anticarcinogenic agents. Therefore, understanding the role of these enzymes and their allele variants in the bioactivation or detoxification of drugs could greatly benefit antineoplastic pharma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98a9fe3377ee46e36c0c5c084f377364
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872008001000015

[Interchangeability of biological drugs: considerations about the approval of biogeneric formulations in Chile]

Autor: Iván, Saavedra S, Luis, Quiñones S

Publikováno v: Revista medica de Chile. 134(12)

Once drug patents expire, the health authorities can approve the registry of similar products. They must request to the manufacturer, the bibliographic background of the original product and the analytical results that certify drug quality. An inspec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5fdf392fca85c0a7df387775b8541af6
https://pubmed.ncbi.nlm.nih.gov/17277878

Estudio de biodisponibilidad comparativa de dos formulaciones de risperidona existentes en el mercado chileno

Autor: Iván Saavedra S, Jaime Solís G, Oscar Schatloff B, Pablo Venegas F, Leonardo E Gaete, Mitzy J Carrillo C

Publikováno v: Revista médica de Chile, Volume: 131, Issue: 5, Pages: 527-534, Published: MAY 2003
Revista médica de Chile v.131 n.5 2003
SciELO Chile
CONICYT Chile
instacron:CONICYT

Background: Bioavailability of a particular drug can vary according to the formulation used. Therefore, studies of comparative bioavailability of different formulations of a same drug are worthwhile. Aim: To compare the bioavailability of two risperi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fbf43e4d9c3697d868182faf3e59e28
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872003000500008&lng=en&tlng=en