[Symptomatic epilepsy in inflammatory demyelinating diseases]

Autor: Na, Totolian, Ev, Borisova, Areg Totolian, Iv, Miliukhina, Sv, Lapin, Kodzaeva AIu, Ln, Prakhova, Ep, Evdoshenko, Ei, Kairbekova, Aa, Skoromets

Publikováno v: Europe PubMed Central

Based on the own observations, we have summarized the features of symptomatic epilepsy in multiple sclerosis and conducted a clinical analysis of the most diagnostically difficult cases of inflammatory and demyelinating diseases in which epilepsy was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::987ddadc6cc5ddd7122ef0e7e64d4c12
http://europepmc.org/abstract/med/21916156

Potential Binding Sites of Pharmacological Chaperone NCGC00241607 on Mutant β-Glucocerebrosidase and Its Efficacy on Patient-Derived Cell Cultures in Gaucher and Parkinson's Disease.

Autor: Kopytova AE; Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Center «Kurchatov Institute», Gatchina 188300, Russia.; Department of Molecular Genetic and Nanobiological Technologies, Pavlov First Saint-Petersburg State Medical University, Saint-Petersburg 197022, Russia., Rychkov GN; Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Center «Kurchatov Institute», Gatchina 188300, Russia.; Institute of Biomedical Systems and Biotechnology, Peter the Great St.Petersburg Polytechnic University, Saint-Petersburg 195251, Russia., Cheblokov AA; Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Center «Kurchatov Institute», Gatchina 188300, Russia., Grigor'eva EV; Institute of Cytology and Genetics Siberian Branch of Russian Academy of Sciences, Novosibirsk 630090, Russia.; Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Novosibirsk 630055, Russia., Nikolaev MA; Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Center «Kurchatov Institute», Gatchina 188300, Russia.; Department of Molecular Genetic and Nanobiological Technologies, Pavlov First Saint-Petersburg State Medical University, Saint-Petersburg 197022, Russia., Yarkova ES; Institute of Cytology and Genetics Siberian Branch of Russian Academy of Sciences, Novosibirsk 630090, Russia., Sorogina DA; Institute of Cytology and Genetics Siberian Branch of Russian Academy of Sciences, Novosibirsk 630090, Russia., Ibatullin FM; Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Center «Kurchatov Institute», Gatchina 188300, Russia., Baydakova GV; Research Centre for Medical Genetics, Moscow 115522, Russia., Izyumchenko AD; Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Center «Kurchatov Institute», Gatchina 188300, Russia.; Department of Molecular Genetic and Nanobiological Technologies, Pavlov First Saint-Petersburg State Medical University, Saint-Petersburg 197022, Russia., Bogdanova DA; Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Center «Kurchatov Institute», Gatchina 188300, Russia., Boitsov VM; Laboratory of Nanobiotechnology, Saint-Petersburg National Research Academic University of the Russian Academy of Sciences, Saint-Petersburg 194021, Russia., Rybakov AV; N.P. Bechtereva Institute of the Human Brain RAS, Saint-Petersburg 197376, Russia., Miliukhina IV; Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Center «Kurchatov Institute», Gatchina 188300, Russia.; N.P. Bechtereva Institute of the Human Brain RAS, Saint-Petersburg 197376, Russia., Bezrukikh VA; Almazov National Medical Research Centre, Saint-Petersburg 197341, Russia., Salogub GN; Almazov National Medical Research Centre, Saint-Petersburg 197341, Russia., Zakharova EY; Research Centre for Medical Genetics, Moscow 115522, Russia., Pchelina SN; Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Center «Kurchatov Institute», Gatchina 188300, Russia.; Department of Molecular Genetic and Nanobiological Technologies, Pavlov First Saint-Petersburg State Medical University, Saint-Petersburg 197022, Russia., Emelyanov AK; Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Center «Kurchatov Institute», Gatchina 188300, Russia.; Department of Molecular Genetic and Nanobiological Technologies, Pavlov First Saint-Petersburg State Medical University, Saint-Petersburg 197022, Russia.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 May 22; Vol. 24 (10). Date of Electronic Publication: 2023 May 22.

Impaired Sphingolipid Hydrolase Activities in Dementia with Lewy Bodies and Multiple System Atrophy.

Autor: Usenko TS; Petersburg Nuclear Physics Institute Named By B.P. Konstantinov of National Research Centre «Kurchatov Institute», 1, mkr. Orlova roshcha, 188300, Gatchina, Russia. usenko_ts@pnpi.nrcki.ru.; Pavlov First Saint-Petersburg State Medical University, L'va Tolstogo str. 6-8, 197022, St. Petersburg, Russia. usenko_ts@pnpi.nrcki.ru., Senkevich KA; Petersburg Nuclear Physics Institute Named By B.P. Konstantinov of National Research Centre «Kurchatov Institute», 1, mkr. Orlova roshcha, 188300, Gatchina, Russia.; Pavlov First Saint-Petersburg State Medical University, L'va Tolstogo str. 6-8, 197022, St. Petersburg, Russia., Bezrukova AI; Petersburg Nuclear Physics Institute Named By B.P. Konstantinov of National Research Centre «Kurchatov Institute», 1, mkr. Orlova roshcha, 188300, Gatchina, Russia., Baydakova GV; Research Center for Medical Genetics, Moskvorechie str. 1, Moscow, 115478, Russia., Basharova KS; Petersburg Nuclear Physics Institute Named By B.P. Konstantinov of National Research Centre «Kurchatov Institute», 1, mkr. Orlova roshcha, 188300, Gatchina, Russia., Zhuravlev AS; Petersburg Nuclear Physics Institute Named By B.P. Konstantinov of National Research Centre «Kurchatov Institute», 1, mkr. Orlova roshcha, 188300, Gatchina, Russia., Gracheva EV; Institute of the Human Brain of RAS, 9, Pavlova str, St. Petersburg, 197376, Russia., Kudrevatykh AV; Institute of the Human Brain of RAS, 9, Pavlova str, St. Petersburg, 197376, Russia., Miliukhina IV; Pavlov First Saint-Petersburg State Medical University, L'va Tolstogo str. 6-8, 197022, St. Petersburg, Russia.; Institute of the Human Brain of RAS, 9, Pavlova str, St. Petersburg, 197376, Russia., Krasakov IV; The Nikiforov Russian Center of Emergency and Radiation Medicine, Optikov str. 54, 197082, St. Petersburg, Russia., Khublarova LA; V.M. Bekhterevs National Medical Research Center Psychiatry and Neurology, 3 Bekhterev str., 192019, St. Petersburg, Russia., Fursova IV; V.M. Bekhterevs National Medical Research Center Psychiatry and Neurology, 3 Bekhterev str., 192019, St. Petersburg, Russia., Zakharov DV; V.M. Bekhterevs National Medical Research Center Psychiatry and Neurology, 3 Bekhterev str., 192019, St. Petersburg, Russia., Timofeeva AA; Pavlov First Saint-Petersburg State Medical University, L'va Tolstogo str. 6-8, 197022, St. Petersburg, Russia., Irishina YA; Institute of the Human Brain of RAS, 9, Pavlova str, St. Petersburg, 197376, Russia., Palchikova EI; V.M. Bekhterevs National Medical Research Center Psychiatry and Neurology, 3 Bekhterev str., 192019, St. Petersburg, Russia., Zalutskaya NM; V.M. Bekhterevs National Medical Research Center Psychiatry and Neurology, 3 Bekhterev str., 192019, St. Petersburg, Russia., Emelyanov AK; Petersburg Nuclear Physics Institute Named By B.P. Konstantinov of National Research Centre «Kurchatov Institute», 1, mkr. Orlova roshcha, 188300, Gatchina, Russia.; Pavlov First Saint-Petersburg State Medical University, L'va Tolstogo str. 6-8, 197022, St. Petersburg, Russia., Zakharova EY; Research Center for Medical Genetics, Moskvorechie str. 1, Moscow, 115478, Russia., Pchelina SN; Petersburg Nuclear Physics Institute Named By B.P. Konstantinov of National Research Centre «Kurchatov Institute», 1, mkr. Orlova roshcha, 188300, Gatchina, Russia.; Pavlov First Saint-Petersburg State Medical University, L'va Tolstogo str. 6-8, 197022, St. Petersburg, Russia.; Institute of Experimental Medicine, 12, Acad. Pavlov Str, 197376, Saint-Petersburg, Russia.

Publikováno v: Molecular neurobiology [Mol Neurobiol] 2022 Apr; Vol. 59 (4), pp. 2277-2287. Date of Electronic Publication: 2022 Jan 23.

Ambroxol increases glucocerebrosidase (GCase) activity and restores GCase translocation in primary patient-derived macrophages in Gaucher disease and Parkinsonism.

Autor: Kopytova AE; Petersburg Nuclear Physics Institute Named By B.P. Konstantinov of National Research Center «Kurchatov Institute», Gatchina, Russia. Electronic address: kopytovaalena@mail.ru., Rychkov GN; Petersburg Nuclear Physics Institute Named By B.P. Konstantinov of National Research Center «Kurchatov Institute», Gatchina, Russia; Peter the Great St.Petersburg Polytechnic University, Saint-Petersburg, Russia; Kurchatov Genome Center - PNPI, Gatchina, Russia., Nikolaev MA; Petersburg Nuclear Physics Institute Named By B.P. Konstantinov of National Research Center «Kurchatov Institute», Gatchina, Russia; First Pavlov State Medical University of St. Petersburg, Saint-Petersburg, Russia., Baydakova GV; Research Center for Medical Genetics, Moscow, Russia., Cheblokov AA; Petersburg Nuclear Physics Institute Named By B.P. Konstantinov of National Research Center «Kurchatov Institute», Gatchina, Russia., Senkevich KA; Petersburg Nuclear Physics Institute Named By B.P. Konstantinov of National Research Center «Kurchatov Institute», Gatchina, Russia; First Pavlov State Medical University of St. Petersburg, Saint-Petersburg, Russia., Bogdanova DA; Petersburg Nuclear Physics Institute Named By B.P. Konstantinov of National Research Center «Kurchatov Institute», Gatchina, Russia., Bolshakova OI; Petersburg Nuclear Physics Institute Named By B.P. Konstantinov of National Research Center «Kurchatov Institute», Gatchina, Russia., Miliukhina IV; Petersburg Nuclear Physics Institute Named By B.P. Konstantinov of National Research Center «Kurchatov Institute», Gatchina, Russia; Institute of Experimental Medicine, Saint-Petersburg, Russia; First Pavlov State Medical University of St. Petersburg, Saint-Petersburg, Russia., Bezrukikh VA; Almazov National Medical Research Centre, Saint-Petersburg, Russia., Salogub GN; Almazov National Medical Research Centre, Saint-Petersburg, Russia., Sarantseva SV; Petersburg Nuclear Physics Institute Named By B.P. Konstantinov of National Research Center «Kurchatov Institute», Gatchina, Russia., Usenko TC; Petersburg Nuclear Physics Institute Named By B.P. Konstantinov of National Research Center «Kurchatov Institute», Gatchina, Russia; First Pavlov State Medical University of St. Petersburg, Saint-Petersburg, Russia., Zakharova EY; Research Center for Medical Genetics, Moscow, Russia., Emelyanov AK; Petersburg Nuclear Physics Institute Named By B.P. Konstantinov of National Research Center «Kurchatov Institute», Gatchina, Russia; Institute of Experimental Medicine, Saint-Petersburg, Russia; First Pavlov State Medical University of St. Petersburg, Saint-Petersburg, Russia., Pchelina SN; Petersburg Nuclear Physics Institute Named By B.P. Konstantinov of National Research Center «Kurchatov Institute», Gatchina, Russia; Institute of Experimental Medicine, Saint-Petersburg, Russia; First Pavlov State Medical University of St. Petersburg, Saint-Petersburg, Russia.

Publikováno v: Parkinsonism & related disorders [Parkinsonism Relat Disord] 2021 Mar; Vol. 84, pp. 112-121. Date of Electronic Publication: 2021 Feb 10.

Plasma cytokine profile in synucleinophaties with dementia.

Autor: Usenko TS; Petersburg Nuclear Physics Institute named by B.P. Konstantinov of National Research Centre, «Kurchatov Institute», Gatchina, Russia; Pavlov First Saint Petersburg State Medical University, Saint-Petersburg, Russia. Electronic address: usenko_ts@pnpi.nrcki.ru., Nikolaev MA; Petersburg Nuclear Physics Institute named by B.P. Konstantinov of National Research Centre, «Kurchatov Institute», Gatchina, Russia; Pavlov First Saint Petersburg State Medical University, Saint-Petersburg, Russia., Miliukhina IV; Petersburg Nuclear Physics Institute named by B.P. Konstantinov of National Research Centre, «Kurchatov Institute», Gatchina, Russia; Pavlov First Saint Petersburg State Medical University, Saint-Petersburg, Russia; Institute of Experimental Medicine, Saint-Petersburg, Russia., Bezrukova AI; Petersburg Nuclear Physics Institute named by B.P. Konstantinov of National Research Centre, «Kurchatov Institute», Gatchina, Russia., Senkevich KA; Petersburg Nuclear Physics Institute named by B.P. Konstantinov of National Research Centre, «Kurchatov Institute», Gatchina, Russia; Pavlov First Saint Petersburg State Medical University, Saint-Petersburg, Russia; Institute of Experimental Medicine, Saint-Petersburg, Russia., Gomzyakova NA; V.M. Bekhterevs National Medical Research Center Psychiatry and Neurology, Saint-Petersburg, Russia., Beltceva YA; V.M. Bekhterevs National Medical Research Center Psychiatry and Neurology, Saint-Petersburg, Russia., Zalutskaya NM; V.M. Bekhterevs National Medical Research Center Psychiatry and Neurology, Saint-Petersburg, Russia., Gracheva EV; Institute of Experimental Medicine, Saint-Petersburg, Russia., Timofeeva AA; Pavlov First Saint Petersburg State Medical University, Saint-Petersburg, Russia., Petrova OA; Pavlov First Saint Petersburg State Medical University, Saint-Petersburg, Russia; Saint-Petersburg Pasteur Institute, Saint-Petersburg, Russia., Semenov AV; Pavlov First Saint Petersburg State Medical University, Saint-Petersburg, Russia; Saint-Petersburg Pasteur Institute, Saint-Petersburg, Russia., Lubimova NE; Saint-Petersburg Pasteur Institute, Saint-Petersburg, Russia., Totolyan AA; Pavlov First Saint Petersburg State Medical University, Saint-Petersburg, Russia; Saint-Petersburg Pasteur Institute, Saint-Petersburg, Russia., Pchelina SN; Petersburg Nuclear Physics Institute named by B.P. Konstantinov of National Research Centre, «Kurchatov Institute», Gatchina, Russia; Pavlov First Saint Petersburg State Medical University, Saint-Petersburg, Russia; Institute of Experimental Medicine, Saint-Petersburg, Russia.

Publikováno v: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia [J Clin Neurosci] 2020 Aug; Vol. 78, pp. 323-326. Date of Electronic Publication: 2020 Apr 23.