Výsledky vyhledávání - "Iulia Macavei"

Akademický článek

Emergence of the Dickeya genus involved duplication of the OmpF porin and the adaptation of the EnvZ-OmpR signaling network

Autor: Clémence Cochard, Marine Caby, Peggy Gruau, Edwige Madec, Michael Marceau, Iulia Macavei, Jérôme Lemoine, Chrystelle Le Danvic, Franck Bouchart, Brigitte Delrue, Sébastien Bontemps-Gallo, Jean-Marie Lacroix

Publikováno v: Microbiology Spectrum, Vol 11, Iss 5 (2023)

ABSTRACT Genome evolution, and more specifically gene duplication, is a key process shaping host–microorganism interaction. The conserved paralogs usually provide an advantage to the bacterium to thrive. If not, these genes become pseudogenes and d

Externí odkaz: https://doaj.org/article/9de8044351a34f62bcb885e7b9342d99

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Akademický článek

Targeted proteomics links virulence factor expression with clinical severity in staphylococcal pneumonia

Autor: Mariane Pivard, Sylvère Bastien, Iulia Macavei, Nicolas Mouton, Jean-Philippe Rasigade, Florence Couzon, Benjamin Youenou, Anne Tristan, Romain Carrière, Karen Moreau, Jérôme Lemoine, François Vandenesch

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)

IntroductionThe bacterial pathogen Staphylococcus aureus harbors numerous virulence factors that impact infection severity. Beyond virulence gene presence or absence, the expression level of virulence proteins is known to vary across S. aureus lineag

Externí odkaz: https://doaj.org/article/94ea01109f9844f7bc8146aa540f9e88

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A single and rapid Zeno SWATH DIA proteomic analysis for concomitant identification and antibiotic resistance profiling of micro-organisms from positive blood cultures

Autor: Iulia Macavei, Eva Peyrache, Maud Gregson, Romain Carrière, Roxane Prat, Chloé Desbiolles, Tiphaine Cecchini, Francis Deforet, Aour Dufour, Pierre L., Delphine Arquier, Olivier Dauwalder, François Vandenesch, Jérôme Lemoine

Publikováno v: Evosep Sepsis Webinar
Evosep Sepsis Webinar, Evosep Biosystems, Feb 2023, Online webinar, France
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International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::04ed3d35cf3221ed3a951cfed4521187
https://hal.science/hal-04004329

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A single and rapid SWATH DIA proteomic analysis for concomitant identification and antibiotic resistance profiling of micro-organisms from positive blood cultures

Publikováno v: 62nd LBMSDG Meeting, The Francis Crick Institute
62nd LBMSDG Meeting, The Francis Crick Institute, London Biological Mass Spectrometry Discussion Group; SCIEX, Dec 2022, London (UK), United Kingdom
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International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::24e69775c6cf4202bf86bf7c3ad5192d
https://hal.science/hal-04000402

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Staphylococcus aureus virulence factor expression matters: input from targeted proteomics shows Panton-Valentine leucocidin impact on mortality

Autor: Mariane Pivard, Sylvere Bastien, Iulia Macavei, Nicolas Mouton, Jean-Philippe Rasigade, Florence Couzon, Romain Carrière, Karen Moreau, Jérôme Lemoine, Francois Vandenesch

In the case of commensal bacteria such as Staphylococcus aureus, the transition from commensalism to invasion and disease as well as disease severity in the course of an infection remain poorly predictable on the sole basis of virulence gene content.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b808c0bb124888db3bf34a427018c4ed
https://doi.org/10.1101/2022.09.18.508069

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Direct and rapid identification of sepsis causative micro-organisms from blood cultures using SCOUT-MRM proteomics assay

Autor: Maud Gregson, Iulia Macavei, Romain Carrière, David Cox, Yves Le Blanc, Tiphaine Cecchini, Roxane Prat, Chloé Desbiolles, Delphine Arquier, Francis Deforet, Eva Peyrache, Mathieu Molimard, Olivier Dauwalder, François Vandenesch, Jérôme Lemoine

Publikováno v: Analytics 2022
Analytics 2022, Sep 2022, Nantes, France
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International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c2877945c759c7ebb2f7219b8d678760
https://hal.science/hal-04001628

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Multiplexed detection and quantification of the protein effectors of antibiotic resistance in clinical strains of Pseudomonas aeruginosa and Enterobacteriaceae by Scout-MRM – Application to positive blood cultures

Autor: Romain Carrière, Nicolas Mouton, Iulia Macavei, Olivier Dauwalder, François Vandenesch, Richard Bonnet, Frédéric Robin, Patrick Plésiat, Jérôme Lemoine

Publikováno v: SMAP2019
SMAP2019, Société Française de Spectrométrie de Masse (SFSM) et la Société Française d’Electrophorèse et Analyse Protéomique (SFEAP), Sep 2019, Strasbourg, France
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International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::48b8b85fa40dbd24c3fd9eddae4b934d
https://hal.archives-ouvertes.fr/hal-02464657

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Fast and accurate identification and antibiotic resistance profiling of micro-organisms in blood cultures by SWATH-MS proteomics

Autor: Iulia Macavei, Eva Peyrache, Maud Gregson, Romain Carrière, Roxane Prat, Chloé Desbiolles, Aour Dufour, Pierre L., Francis Deforet, Tiphaine Cecchini, Olivier Dauwalder, François Vandenesch, Jérôme Lemoine

Publikováno v: HAL
SCIEX Breakfast Seminar, The pursuit of new biomarkers, 70th Conference on Mass Spectrometry and Allied Topics
SCIEX Breakfast Seminar, The pursuit of new biomarkers, 70th Conference on Mass Spectrometry and Allied Topics, American Society for Mass Spectrometry; SCIEX, Jun 2022, Minneapolis (Minnesota), United States
70th Conference on Mass Spectrometry and Allied Topics
70th Conference on Mass Spectrometry and Allied Topics, American Society for Mass Spectrometry, Jun 2022, Minneapolis (Minnesota), United States
Advances in Proteomics & Metabolomics 2022
Advances in Proteomics & Metabolomics 2022, Technology Networks; SCIEX, Sep 2022, Online webinar, United Kingdom

International audience; IntroductionToday, approximately 1.3 million people die each year worldwide from bacterial antimicrobial resistance (AMR). AMR is of great concern in the context of bloodstream infections (BSIs) when it evolves into sepsis. If

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1a26152cfcc69e36d04cff0050f04745
https://hal.science/hal-04001057

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