Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Iu V, Khropov"'
Publikováno v:
Voprosy meditsinskoi khimii. 46(4)
Experiments on chronically instrumented Wistar rats demonstrated that 15 mm microsphere embolization of coronary arteries led to a significant decrease in the systemic (APsyst) and maximal left ventricular systolic pressures (LVSPmax) to 10.1 and 21.
Publikováno v:
Biokhimiia (Moscow, Russia). 58(1)
Interactions of the bacteriophage T7 DNA-dependent RNA polymerase with three GTP analogs have been studied. All of the three analogs tested contained substituted naphthalenesulphamide groups and were shown to be under appropriate conditions irreversi
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 55(4)
A site-selective analogue of the cyclic adenosine monophosphate 8-chloro-adenosine-3',5'-cyclophosphate was studied for its effects on the growth of transplanted murine melanoma B-16. When the agent was given to the mice, a substantial effect on the
Publikováno v:
Biokhimiia (Moscow, Russia). 56(10)
Inhibition of rabbit skeletal muscle glycogen synthase I was studied by using several synthetic substrate analogs: dansylhydrazone of oxo-UDP, 3-hydroxy-2-naphthoylhydrazone of oxo-UDP, salicyloylhydrazone of oxo-UDP, 1-oxyl-2,2,5,5-tetramethylpyrrol
Publikováno v:
Biokhimiia (Moscow, Russia). 55(9)
The effect of N-(omega-aminoalkyl) derivatives of naphthalene-1-sulfamide on the activity of soluble guanylate cyclase and on human platelet aggregation at the first (reversible) step of the guanylate cyclase reaction was studied. Low (approximately
Autor:
A Kh, Akbarov, V L, Tunitskaia, L A, Baranova, Iu V, Khropov, M M, Krasil'nikova, S N, Kochetkov
Publikováno v:
Biokhimiia (Moscow, Russia). 55(5)
The NTP binding site of bacteriophage T7 DNA-dependent RNA polymerase was studied using GTP analogs. For four analogs the irreversible inhibition was demonstrated. The kinetic parameters for competitive (Ki) and irreversible (KI and k3) inhibition we
Publikováno v:
Biokhimiia (Moscow, Russia). 42(10)
A new method for synthesis of nucleoside-5'-phosphonates containing a reactive halogen atom in the phosphonate residue has been developed. In order to achieve selective inhibition of individual enzymes and to elucidate the structure of their active s
Publikováno v:
Biokhimiia (Moscow, Russia). 48(12)
Preincubation of rabbit skeletal muscle glycogen synthase I with 5'(p-fluorosulfonylbenzoyl)uridine (p-FSBU) or 5'-(m-fluorosulfonylbenzoyl)uridine (m-FSBU) results in a decrease of the enzymatic activity with time. UDP, the product of the glycogen s
Publikováno v:
Biokhimiia (Moscow, Russia). 47(10)
In order to investigate the regulatory properties of dopamine-sensitive adenylate cyclase from bovine brain caudate nucleus some non-hydrolyzed guanyl nucleotides modified at the 8th position of the purine base and at phosphate site were synthesized.
Publikováno v:
Biokhimiia (Moscow, Russia). 47(2)
Adenylate cyclase from rabbit heart membranes is irreversibly inhibited by 2',3'-dialdehyde of ATP (oxo-ATP). The inhibiting effects is observed during membrane incubation with the inhibitor. Sodium borohydride increase the degree of the enzyme inact