Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Iu P, Lysov"'
Autor:
D Iu, Galaktionova, O A, Gra, I I, Nizamutdinov, V E, Shershov, V E, Kuznetsova, A V, Chudinov, A E, Gareeva, D F, Zakirov, E K, Khusnutdinova, Iu P, Lysov, T V, Nasedkina
Publikováno v:
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 112(10)
We have developed a biochip for the analysis of candidate genes for schizophrenia. Using this biochip, allele and genotype frequencies for the polymorphisms of HTR2A, BDNF and SLC6A4 genes in 198 patients with schizophrenia and 192 healthy individual
Autor:
V E, Barskiĭ, E E, Egorov, É Ia, Kreĭndlin, Iu P, Lysov, S V, Pan'kov, D A, Iurasov, R A, Iurasov, A S, Zasedatelev
Publikováno v:
Biofizika. 57(3)
This paper discusses an issue on the development of biophysical methods for biochip analysis. A scheme and construction of a biochip analyzer based on wide-field digital fluorescence microscopy are described. The analyzer is designed to register imag
Autor:
O N, Mitiaeva, D O, Fesenko, T V, Nasedkina, Iu P, Lysov, V E, Barskiĭ, A S, Zasedatelev, P L, Ivanov
Publikováno v:
Sudebno-meditsinskaia ekspertiza. 50(2)
The article describes the method defining 5 alleles of ABO blood group typing system by molecular hybridization in hydrogel oligonucleotide microchip. The testing points were SNP variants in positions 261 and 297of exon 6 and in positions 646 and 657
Autor:
A M, Kolchinskiĭ, D A, Griadunov, Iu P, Lysov, V M, Mikhaĭlovich, T V, Nasedkina, A Iu, Turygin, A Iu, Rubina, V E, Barskiĭ, A S, Zasedatelev
Publikováno v:
Molekuliarnaia biologiia. 38(1)
The review describes the history of creation and development of the microchip technology and its role in the human genome project in Russia. The emphasis is placed on the three-dimensional gel-based microchips developed at the Center of Biological Mi
Autor:
A A, Chernyĭ, K A, Trushkin, V A, Bokovoĭ, A K, Ianovskiĭ, N V, Tverdokhlebov, A V, Zhukov, Iu P, Lysov
Publikováno v:
Molekuliarnaia biologiia. 38(1)
A distributed computing system is developed to search and analyze genetic databases using parallel computing technologies. Queries are processed by a local network PC cluster. A universal task and data exchange format is developed for effective query
Publikováno v:
Molekuliarnaia biologiia. 36(4)
The MAGIChip (MicroArrays of Gel-Immobilized Compounds on a chip) consists of an array of hydrophilic gel pads fixed on a hydrophobic glass surface. These pads of several picoliters to several nanoliters in volume contain the gel-immobilized nucleic
Publikováno v:
Molekuliarnaia biologiia. 28(6)
De novo design and synthesis by a solid phase technique of linear and cyclic 26-residues peptides are reported. The peptides use beta-strand-turn-beta -strand motif for sequence recognition on DNA. Amino acid sequences in the two peptides are identic
Publikováno v:
Molekuliarnaia biologiia. 28(3)
DNA sequencing by hybridization on oligonucleotide matrix (SHOM) makes use of a matrix of immobilized oligonucleotides. Yet the method is not directly applicable for sequencing of fragments with long monotonous repeats. Measurement of the distances b
Publikováno v:
Molekuliarnaia biologiia. 27(5)
The efficiency of additional rounds of continuous stacking hybridization in DNA sequence reconstruction by hybridization with oligonucleotide matrix (SHOM) is considered. At first, DNA is hybridized with a matrix of oligonucleotides of the length L.
Autor:
A K, Shchelkina, O K, Mamaeva, O F, Borisova, Iu P, Lysov, E N, Timofeev, I A, Il'icheva, B P, Gottikh, V L, Florent'ev
Publikováno v:
Molekuliarnaia biologiia. 26(6)
The temperature dependence of the UV- and CD-spectra of the oligonucleotides 3'-d(A)10-L-(T)10-5' [anti(AT)], 3'-d(A)10-L-d(T)10-3' [par(AT)] and 3'-d(A)10-L-(dT)10-L-(dT)10-5' [tripl(ATT)] (L = -PO(CH2CH2O) 3p-) in the phosphate buffer at pH 7 under