Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Iu N, Utkin"'
Publikováno v:
Russian Journal of Bioorganic Chemistry. 32:103-115
alpha-Conotoxins, peptide neurotoxins from poisonous marine snails of the genus Conus that highly specifically block nicotinic acetylcholine receptors (AChRs) of various types, are reviewed. Preliminarily, the structural organization of AChRs of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffb164461fc39cf6bcdb22780a26254c
https://doi.org/10.1134/s1068162006020014
https://doi.org/10.1134/s1068162006020014
Publikováno v:
Russian Journal of Bioorganic Chemistry. 27:72-83
Resonances in the two-dimensional 1H NMR spectra of a weak toxin (WTX) from the venom of cobra Naja kaouthia for all 65 amino acid residues were assigned. The amino acid sequence of WTX, determined by the sequentional assignment of spin systems, was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::437bb8b277e44007de17eb62f9b49b4d
https://doi.org/10.1023/a:1011376918514
https://doi.org/10.1023/a:1011376918514
Publikováno v:
Bioorganicheskaia khimiia. 37(3)
Serine proteinases and Kunitz type inhibitors are widely represented in venoms of snakes from different genera. During the study of the venoms from snakes inhabiting Russia we have cloned cDNAs encoding new proteins belonging to these protein familie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b81ddeb5a8ffd541b0ca0cbea8ea4a92
https://pubmed.ncbi.nlm.nih.gov/21899053
https://pubmed.ncbi.nlm.nih.gov/21899053
Publikováno v:
Bioorganicheskaia khimiia. 29(4)
A sensitive nonradioactive method for detection of substances interacting with the neuronal nicotinic acetylcholine alpha 7-type receptor (AChR) was proposed. The method uses biotinylated alpha-cobratoxin (Bt-CTX) and is based on the ability of the N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d2a482c58845d06147eb92e65ceb8543
https://pubmed.ncbi.nlm.nih.gov/12947760
https://pubmed.ncbi.nlm.nih.gov/12947760
Publikováno v:
Bioorganicheskaia khimiia. 28(2)
Two photoactivatable analogues of alpha-conotoxin GI with the benzoylphenylalanine residue (Bpa) substituted for His10 or Tyr11 were synthesized using the method of solid-phase peptide synthesis. In addition, alpha-conotoxin MI was chemically modifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8319f5ec8b104aa6d36b3ce74dbfd014
https://pubmed.ncbi.nlm.nih.gov/11962231
https://pubmed.ncbi.nlm.nih.gov/11962231
Autor:
V V, Kukhtina, K, Weise, A V, Osipov, V G, Starkov, M I, Titov, S E, Esipov, T V, Ovchinnikova, V I, Tsetlin, Iu N, Utkin
Publikováno v:
Bioorganicheskaia khimiia. 26(11)
By MALDI MS, we searched cobra venoms for new low-content polypeptides. A number of new proteins with molecular masses 7-25 kDa, characteristic of the known snake protein toxins, were identified, with the content of one of them less than 0.02%.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::744ade02fd524215e0c7b27f9a254ccc
https://pubmed.ncbi.nlm.nih.gov/11696890
https://pubmed.ncbi.nlm.nih.gov/11696890
Autor:
A V, Osipov, C, Weise, P, Franke, V V, Kukhtina, S, Frings, F, Hucho, V I, Tsetlin, Iu N, Utkin
Publikováno v:
Bioorganicheskaia khimiia. 27(3)
Amino acid sequences of several fragments of the 25 k protein (molecular mass 24,953 Da) previously isolated from cobra Naja kaouthia (Kukhtina et al. Bioorg. Khim., 2000, vol. 26, pp. 803-807) were determined. Their comparison with the primary struc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7e827954470b5ac447fd0bcd0098de6f
https://pubmed.ncbi.nlm.nih.gov/11443947
https://pubmed.ncbi.nlm.nih.gov/11443947
Publikováno v:
Bioorganicheskaia khimiia. 27(2)
Cytotoxin II from the venom of the Central-Asian cobra Naja oxiana spin-labeled at Lys35 (SLCT II) was studied by ESR spectroscopy in aqueous solution and upon interaction with phospholipid vesicles from egg phosphatidylcholine or its mixture with di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4a8ef102eb39f7680e01f2380ea10263
https://pubmed.ncbi.nlm.nih.gov/11357394
https://pubmed.ncbi.nlm.nih.gov/11357394
Autor:
Iu N, Utkin
Publikováno v:
Bioorganicheskaia khimiia. 26(1)
The application of photoactivatable derivatives for studies of different types of neuroreceptors belonging to two superfamilies, G-protein dependent receptors and ligand-gated ionic channels, is discussed. Studies of the structure of voltage-gated an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3caae2eeda5fa0fc9016aecb9943e1fc
https://pubmed.ncbi.nlm.nih.gov/10806548
https://pubmed.ncbi.nlm.nih.gov/10806548
Autor:
Iu N, Utkin, P V, Dubovskiĭ, M A, Dubinnyĭ, V A, Zharavin, T N, Simonova, L I, Barsukov, A S, Arsen'ev
Publikováno v:
Bioorganicheskaia khimiia. 25(12)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a38272c28a258a255d04370116cba934
https://pubmed.ncbi.nlm.nih.gov/10734553
https://pubmed.ncbi.nlm.nih.gov/10734553