Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Iu D, Nechipurenko"'
Autor:
D Iu, Nechupurenko, I A, Il'icheva, M V, Khodykov, M S, Poptsova, Iu D, Nechipurenko, S L, Grokhovskiĭ
Publikováno v:
Biofizika. 59(6)
This study offers a simulation of the stretching dynamics of a double-stranded DNA fragment in the high-gradient flow of fluid near collapsing cavitation bubbles. Calculated profiles of elastic tension along the model of a polymer fragment were used
Publikováno v:
Biofizika. 58(6)
The study reports a thermodynamic model describing microarray oligo-target hybridization. The relationship between hybridization signal intensity and Gibbs free energy change for oligo-target duplex formation was our function of interest. The behavio
Autor:
S L, Grokhovskiĭ, I A, Il'icheva, L A, Panchenko, M V, Golovkin, D Iu, Nechipurenko, R V, Polozov, Iu D, Nechipurenko
Publikováno v:
Biofizika. 58(1)
We investigated a phenomenon of ultrasonic cleavage of DNA complexed with transition metal cations Ag(I), Cu(II) and Hg(II). We found the statistically significant dependence of relative intensity of cleavage on cation type and concentration. Each ca
Publikováno v:
Biofizika. 56(6)
Ligand binding to DNA, as well as to microarrays, requires a system approach to description and analysis. This type of approach implies a fixed sequence of operations. Firstly, it is necessary to make a description of a binding scheme that realizes l
Autor:
N N, Vtiurina, S L, Grokhovskiĭ, I V, Filimonov, O I, Medvedkov, D Iu, Nechipurenko, S A, Vasil'ev, Iu D, Nechipurenko
Publikováno v:
Biofizika. 56(3)
The cleavage of dsDNA fragments in aqueous solution after irradiation with UV laser pulses at 193 nm has been studied. Samples were investigated using polyacrylamide gel electrophoresis. The intensity of damage of particular phosphodiester bond after
Publikováno v:
Biofizika. 54(5)
A simple thermodynamic model describing the microarray oligo-target hybridization has been constructed. The relationship between the hybridization signal intensity and Gibbs free energy for oligo-target duplex formation has been considered. The behav
Publikováno v:
Biofizika. 54(4)
The regulation of the reporter gene activity in a single bacterial cell by means of lambda-phage C1 repressor has been described by the methods of statistical thermodynamics. The equations for the calculation of the mean production rate of the report
Autor:
S L, Grokhovskiĭ, I A, Il'icheva, D Iu, Nechipurenko, L A, Panchenko, R V, Polozov, Iu D, Nechipurenko
Publikováno v:
Biofizika. 53(3)
A method for studying the local inhomogeneities of DNA and its dynamics is proposed. The method is based on the combination of two procedures, splitting the DNA molecules by ultrasound and analysis of DNA fragments obtained by gel electrophoresis. Th
Publikováno v:
Biofizika. 52(4)
The binding of chitosan molecules to DNA in solutions of different ionic strength has been studied. The data were analyzed in terms of the model of ion condensation and the thermodynamic theory of the binding of protracted ligands to DNA. Combining t
Publikováno v:
Biofizika. 50(6)
The temperature stability of nanoconstructions formed by double-stranded DNA molecules fixed in the structure of their liquid crystalline dispersions and cross-linked by nanobridges was determined. It was shown that the heating of nanoconstructions i