Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Itzy E. Morales Pantoja"'
Publikováno v:
Frontiers in Artificial Intelligence, Vol 6 (2024)
Human brain organoids, aka cerebral organoids or earlier “mini-brains”, are 3D cellular models that recapitulate aspects of the developing human brain. They show tremendous promise for advancing our understanding of neurodevelopment and neurologi
Externí odkaz:
https://doaj.org/article/c8365d4f096a47f98575bc59d8fa4099
Autor:
Itzy E. Morales Pantoja, Lena Smirnova, Alysson R. Muotri, Karl J. Wahlin, Jeffrey Kahn, J. Lomax Boyd, David H. Gracias, Timothy D. Harris, Tzahi Cohen-Karni, Brian S. Caffo, Alexander S. Szalay, Fang Han, Donald J. Zack, Ralph Etienne-Cummings, Akwasi Akwaboah, July Carolina Romero, Dowlette-Mary Alam El Din, Jesse D. Plotkin, Barton L. Paulhamus, Erik C. Johnson, Frederic Gilbert, J. Lowry Curley, Ben Cappiello, Jens C. Schwamborn, Eric J. Hill, Paul Roach, Daniel Tornero, Caroline Krall, Rheinallt Parri, Fenna Sillé, Andre Levchenko, Rabih E. Jabbour, Brett J. Kagan, Cynthia A. Berlinicke, Qi Huang, Alexandra Maertens, Kathrin Herrmann, Katya Tsaioun, Raha Dastgheyb, Christa Whelan Habela, Joshua T. Vogelstein, Thomas Hartung
Publikováno v:
Frontiers in Artificial Intelligence, Vol 6 (2023)
The brain is arguably the most powerful computation system known. It is extremely efficient in processing large amounts of information and can discern signals from noise, adapt, and filter faulty information all while running on only 20 watts of powe
Externí odkaz:
https://doaj.org/article/aebc0f0cd878418ebed9205a612b1932
Autor:
Xitiz Chamling, Alyssa Kallman, Weixiang Fang, Cynthia A. Berlinicke, Joseph L. Mertz, Prajwal Devkota, Itzy E. Morales Pantoja, Matthew D. Smith, Zhicheng Ji, Calvin Chang, Aniruddha Kaushik, Liben Chen, Katharine A. Whartenby, Peter A. Calabresi, Hai-Quan Mao, Hongkai Ji, Tza-Huei Wang, Donald J. Zack
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Brain myelinating oligodendrocytes are rare and difficult to isolate, which has limited data on their development. Here the authors develop a reporter for scalable purification of human pluripotent stem cell derived oligodendrocyte lineage cells, and
Externí odkaz:
https://doaj.org/article/e96ddf8af967458184f40a76c755772f
Autor:
Thomas Hartung, Lena Smirnova, Itzy E. Morales Pantoja, Akwasi Akwaboah, Dowlette-Mary Alam El Din, Cynthia A. Berlinicke, J. Lomax Boyd, Brian S. Caffo, Ben Cappiello, Tzahi Cohen-Karni, J. Lowry Curley, Ralph Etienne-Cummings, Raha Dastgheyb, David H. Gracias, Frederic Gilbert, Christa Whelan Habela, Fang Han, Timothy D. Harris, Kathrin Herrmann, Eric J. Hill, Qi Huang, Rabih E. Jabbour, Erik C. Johnson, Brett J. Kagan, Caroline Krall, Andre Levchenko, Paul Locke, Alexandra Maertens, Monica Metea, Alysson R. Muotri, Rheinallt Parri, Barton L. Paulhamus, Jesse D. Plotkin, Paul Roach, July Carolina Romero, Jens C. Schwamborn, Fenna Sillé, Alexander S. Szalay, Katya Tsaioun, Daniel Tornero, Joshua T. Vogelstein, Karl J. Wahlin, Donald J. Zack
Publikováno v:
Frontiers in Science. 1
We, the participants of the First Organoid Intelligence Workshop - "Forming an OI Community" (22-24 February 2022), call on the international scientific community to explore the potential of human brain-based organoid cell cultures to advance our und
Autor:
Qi Huang, Bohao Tang, July Carolina Romero, Yuqian Yang, Saifeldeen Khalil Elsayed, Gayatri Pahapale, Tien-Jung Lee, Itzy E. Morales Pantoja, Fang Han, Cynthia Berlinicke, Terry Xiang, Mallory Solazzo, Thomas Hartung, Zhao Qin, Brian S. Caffo, Lena Smirnova, David H. Gracias
Publikováno v:
Science advances. 8(33)
Brain organoids are important models for mimicking some three-dimensional (3D) cytoarchitectural and functional aspects of the brain. Multielectrode arrays (MEAs) that enable recording and stimulation of activity from electrogenic cells are widely ut
Autor:
Oscar A. Bizzozero, Mara Nydes, Tamara Howard, Chelin Hu, Itzy E. Morales Pantoja, Kara L. Shanley
Publikováno v:
Journal of Neurochemistry. 148:426-439
Glutathione peroxidase 4 (GPx4) is the only enzyme capable of reducing toxic lipid hydroperoxides in biological membranes to the corresponding alcohols using glutathione as the electron donor. GPx4 is the major inhibitor of ferroptosis, a non-apoptot
Autor:
Vasiliki Mahairaki, Matthew D. Smith, Kathryn C. Fitzgerald, Linzhao Cheng, Katharine A. Whartenby, Arun Venkatesan, Yongxing Gao, Peter A. Calabresi, Labchan Rajbhandari, Itzy E. Morales Pantoja
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0233980 (2020)
PLoS ONE
PLoS ONE
Multiple sclerosis (MS) is an inflammatory and demyelinating disease of the central nervous system (CNS) that results in variable severities of neurodegeneration. The understanding of MS has been limited by the inaccessibility of the affected cells a
Publikováno v:
Journal of Neuroimmunology. 339:577115
Multiple sclerosis (MS) is an autoimmune disease that remains in need of effective therapies. Plant-derived medicines have appealing properties for the treatment of autoimmune diseases. MYMD-1 is a synthetic plant alkaloid that has been shown to amel
Autor:
Oscar A. Bizzozero, Jianzheng Zheng, Itzy E. Morales Pantoja, Chelin Hu, Nora I. Perrone-Bizzozero
This study investigates the possible mechanism(s) underlying glutathione (GSH) deficiency in the mouse spinal cord during the course of myelin oligodendrocyte glycoprotein35-55 peptide-induced experimental autoimmune encephalomyelitis (EAE), a common
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a034820ed11e5ad5ee217de18a2c3b25
https://europepmc.org/articles/PMC5118114/
https://europepmc.org/articles/PMC5118114/
Autor:
Itzy E Morales Pantoja, Matthew D Smith, Labchan Rajbhandari, Linzhao Cheng, Yongxing Gao, Vasiliki Mahairaki, Arun Venkatesan, Peter A Calabresi, Kathryn C Fitzgerald, Katharine A Whartenby
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0233980 (2020)
Multiple sclerosis (MS) is an inflammatory and demyelinating disease of the central nervous system (CNS) that results in variable severities of neurodegeneration. The understanding of MS has been limited by the inaccessibility of the affected cells a
Externí odkaz:
https://doaj.org/article/575b8464d15d450992578ce877033aa5