Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Itziar Echeverria"'
Autor:
Aintzane Zabaleta, Delia D'Avola, Itziar Echeverria, Diana Llopiz, Leyre Silva, Lorea Villanueva, José Ignacio Riezu-Boj, Esther Larrea, Alexander Pereboev, Juan José Lasarte, Iago Rodriguez-Lago, Mercedes Iñarrairaegui, Bruno Sangro, Jesús Prieto, Pablo Sarobe
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 2, Iss , Pp - (2015)
The lack of antiviral cellular immune responses in patients with chronic hepatitis C virus (HCV) infection suggests that T-cell vaccines may provide therapeutic benefit. Due to the central role that dendritic cells (DC) play in the activation of T-ce
Externí odkaz:
https://doaj.org/article/a824b1a51cd6450d8b80d26a263f2b52
Autor:
Jose-I. Riezu-Boj, Maria P. Civeira, Iosu Sola, Laura Guembe, Jesús Prieto, Rafael Aldabe, Esther Larrea, Pablo Sarobe, Itziar Echeverria
Publikováno v:
Journal of Hepatology. 60:482-489
Background & Aims Oncostatin M (OSM) is an inflammatory cytokine which interacts with a heterodimeric receptor formed by gp130 and either OSMRβ or LIFR. Here we have analysed OSM and its receptors in livers with chronic hepatitis C (CHC) and studied
Autor:
Flavia Piccioni, Mariana Malvicini, Laura Alaniz, Pablo Sarobe, Itziar Echeverria, Manglio Rizzo, Juan Bayo, Catalina Atorrasagasti, Mariana Garcia, Guillermo Mazzolini, Jorge B. Aquino
Publikováno v:
Cancer Immunology, Immunotherapy. 60:1383-1395
We have recently shown that systemic administration of low molecular weight hyaluronan (LMW HA) significantly reduces colorectal carcinoma (CRC) growth in vivo. The elicited response is partially mediated by activated dendritic cells (DC). To potenti
Autor:
Juan José Lasarte, Pablo Sarobe, Leyre Silva, Itziar Echeverria, Francisco Borrás-Cuesta, Maria Cubero, Jose I Riezu-Boj, Jesús Prieto, Marta Bes, Juan Ignacio Esteban, Alexander Pereboev, Aintzane Zabaleta
Publikováno v:
Hepatology. 54:28-37
Injection of dendritic cells (DCs) presenting viral proteins constitutes a promising approach to stimulate T cell immunity against hepatitis C virus (HCV). Here we describe a strategy to enhance antigen loading and immunostimulatory functions of DCs
Autor:
Iago Rodríguez-Lago, Bruno Sangro, Diana Llopiz, Esther Larrea, Delia D'Avola, Jesús Prieto, Mercedes Iñarrairaegui, Alexander Pereboev, Pablo Sarobe, Itziar Echeverria, Aintzane Zabaleta, Lorea Villanueva, Jose I Riezu-Boj, Juan José Lasarte, Leyre Silva
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 2, Iss, Pp-(2015)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
The lack of antiviral cellular immune responses in patients with chronic hepatitis C virus (HCV) infection suggests that T-cell vaccines may provide therapeutic benefit. Due to the central role that dendritic cells (DC) play in the activation of T-ce
Autor:
Itziar Echeverria, Anangi Balasiddaiah, Pablo Sarobe, Jose-I. Riezu-Boj, Pablo Gastaminza, Laura Guembe, Jesús Prieto, Maria P. Civeira, Esther Larrea, Rafael Aldabe
Publikováno v:
Gut. 63(4)
Background IL-7 and IL-15 are produced by hepatocytes and are critical for the expansion and function of CD8 T cells. IL-15 needs to be presented by IL-15Rα for efficient stimulation of CD8 T cells. Methods We analysed the hepatic levels of IL-7, IL
Autor:
Lorea Manterola, Itziar Echeverria, Nancy Díaz-Valdés, Pablo Sarobe, Jean-Michel Pawlotsky, Jacinto López-Sagaseta, Francisco Borrás-Cuesta, Hervé Lerat, Virginia Belsúe, Diana Llopiz, Jesús Prieto, Esther Larrea, Juan José Lasarte, Jose I Riezu-Boj
Publikováno v:
Hepatology (Baltimore, Md.). 53(1)
The high levels of interleukin 10 (IL-10) present in chronic hepatitis C virus (HCV) infection have been suggested as responsible for the poor antiviral cellular immune responses found in these patients. To overcome the immunosuppressive effect of IL
Autor:
Pablo Sarobe, Esther Larrea, Victor Segura, Jesús Prieto, Itziar Echeverria, Iranzu González, Rafael Aldabe
Publikováno v:
Dadun. Depósito Académico Digital de la Universidad de Navarra
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Oncostatin M (OSM) is released together with type I interferon (IFN) by activated dendritic cells, suggesting a concerted action of these cytokines in the biological response against infection. We found that OSM increases the antiviral effect of IFN-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0d716f2b16c8e66ed76ae8ec58f7edc
https://europepmc.org/articles/PMC2655580/
https://europepmc.org/articles/PMC2655580/
Autor:
Itziar Echeverria, N. Diaz-Valdes, Pablo Sarobe, Juan José Lasarte, Leyre Silva, Jose I Riezu-Boj, M. P. Civeira, F. Borrás‐Cuesta, Aintzane Zabaleta, Jesús Prieto
Publikováno v:
Journal of Viral Hepatitis.
Summary. Dendritic cells (DC) transfected with an adenovirus encoding hepatitis C virus (HCV) NS3 protein (AdNS3) induce potent antiviral immune responses when used to immunize mice. However, in HCV infected patients, controversial results have been