Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Itzhak Nissim"'
Autor:
Suhail Khoja, Xiao-Bo Liu, Brian Truong, Matthew Nitzahn, Jenna Lambert, Adam Eliav, Eram Nasser, Emma Randolph, Kristine E. Burke, Rebecca White, Xuling Zhu, Paolo G.V. Martini, Itzhak Nissim, Stephen D. Cederbaum, Gerald S. Lipshutz
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 28, Iss , Pp 859-874 (2022)
Arginase deficiency is associated with prominent neuromotor features, including spastic diplegia, clonus, and hyperreflexia; intellectual disability and progressive neurological decline are other signs. In a constitutive murine model, we recently des
Externí odkaz:
https://doaj.org/article/27c6ab38d6da42bdbac80e2bb9c3a868
Autor:
Suhail Khoja, Jenna Lambert, Matthew Nitzahn, Adam Eliav, YuChen Zhang, Mikayla Tamboline, Colleen T. Le, Eram Nasser, Yunfeng Li, Puja Patel, Irina Zhuravka, Lindsay M. Lueptow, Ilona Tkachyova, Shili Xu, Itzhak Nissim, Andreas Schulze, Gerald S. Lipshutz
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 25, Iss , Pp 278-296 (2022)
Creatine deficiency disorders are inborn errors of creatine metabolism, an energy homeostasis molecule. One of these, guanidinoacetate N-methyltransferase (GAMT) deficiency, has clinical characteristics that include features of autism, self-mutilatio
Externí odkaz:
https://doaj.org/article/87a7fdb6ecd04a129c24284a36c20cca
Autor:
Sanika Khare, Laura C. Kim, Graham Lobel, Paschalis-Thomas Doulias, Harry Ischiropoulos, Itzhak Nissim, Brian Keith, M. Celeste Simon
Publikováno v:
Cancer & Metabolism, Vol 9, Iss 1, Pp 1-16 (2021)
Abstract Background Kidney cancer is a common adult malignancy in the USA. Clear cell renal cell carcinoma (ccRCC), the predominant subtype of kidney cancer, is characterized by widespread metabolic changes. Urea metabolism is one such altered pathwa
Externí odkaz:
https://doaj.org/article/c58358261d474004af1c1f7c4c61d199
Autor:
Pearl Lee, Dania Malik, Nicholas Perkons, Peiwei Huangyang, Sanika Khare, Seth Rhoades, Yao-Yu Gong, Michelle Burrows, Jennifer M. Finan, Itzhak Nissim, Terence P. F. Gade, Aalim M. Weljie, M. Celeste Simon
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Glutamine is an energetic source required for the proliferation of cancer cells. Here, the authors show that soft tissue sarcomas expressing high levels of glutaminase (GLS) are particularly sensitive to glutamine starvation and GLS inhibition in tum
Externí odkaz:
https://doaj.org/article/3b907274e9ce47de86b2c4ff4f6b6ad0
Akademický článek
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Autor:
Pantalia, Meghan, Lin, Zhi, Tener, Samantha J., Qiao, Bing, Tang, Grace, Ulgherait, Matthew, O'Connor, Reed, Delventhal, Rebecca, Volpi, Julia, Syed, Sheyum, Itzhak, Nissim, Canman, Julie C., Fernández, María Paz, Shirasu-Hiza, Mimi
Publikováno v:
Scientific Reports; 11/20/2023, Vol. 13 Issue 1, p1-18, 18p
Autor:
Hui Feng, M. Celeste Simon, Guoliang Qing, A. Thomas Look, Itzhak Nissim, Shizhen Zhu, Ting Tao, Amandeep S. Saini, Annie Kennedy, Nicolas Skuli, Rindert Missiaen, Jacob Athoe, Andrew Lam, Jennifer M. Finan, Xiaodan Qin, Nicole M. Anderson
Sup. Figure 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03dc58817a553efa9ac0016de641b137
https://doi.org/10.1158/0008-5472.22429140
https://doi.org/10.1158/0008-5472.22429140
Autor:
Hui Feng, M. Celeste Simon, Guoliang Qing, A. Thomas Look, Itzhak Nissim, Shizhen Zhu, Ting Tao, Amandeep S. Saini, Annie Kennedy, Nicolas Skuli, Rindert Missiaen, Jacob Athoe, Andrew Lam, Jennifer M. Finan, Xiaodan Qin, Nicole M. Anderson
Supplemental Method and Materials; Supplemental Figure Legends; Goes with the Longer version of the paper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44bae495b4c625e2a1fb61a63e288dc7
https://doi.org/10.1158/0008-5472.22429128
https://doi.org/10.1158/0008-5472.22429128
Autor:
Hui Feng, M. Celeste Simon, Guoliang Qing, A. Thomas Look, Itzhak Nissim, Shizhen Zhu, Ting Tao, Amandeep S. Saini, Annie Kennedy, Nicolas Skuli, Rindert Missiaen, Jacob Athoe, Andrew Lam, Jennifer M. Finan, Xiaodan Qin, Nicole M. Anderson
High-risk neuroblastoma remains therapeutically challenging to treat, and the mechanisms promoting disease aggression are poorly understood. Here, we show that elevated expression of dihydrolipoamide S-succinyltransferase (DLST) predicts poor treatme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ffdb6413c88ab6fda199aadcd62c9ee
https://doi.org/10.1158/0008-5472.c.6513255.v1
https://doi.org/10.1158/0008-5472.c.6513255.v1
Autor:
Estibaliz Castillero, Emmett Fitzpatrick, Samuel J. Keeney, Alex M. D’Angelo, Benjamin B. Pressly, Michael T. Simpson, Mangesh Kurade, W. Clinton Erwin, Vivian Moreno, Chiara Camillo, Halley J. Shukla, Vaishali V. Inamdar, Arbi Aghali, Juan B. Grau, Elisa Salvati, Itzhak Nissim, Lubica Rauova, Mark A. Oyama, Stanley J. Stachelek, Chase Brown, Abba M. Krieger, Robert J. Levy, Giovanni Ferrari
Publikováno v:
Sci Transl Med
Degenerative mitral valve (MV) regurgitation (MR) is a highly prevalent heart disease that requires surgery in severe cases. Here, we show that a decrease in the activity of the serotonin transporter (SERT) accelerates MV remodeling and progression t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b905f7779efd561ae31c4dfab90771f
https://europepmc.org/articles/PMC9896655/
https://europepmc.org/articles/PMC9896655/