Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Itzchak Angel"'
Autor:
Yaron D. Barac, Orit Bar-Am, Esti Liani, Tamar Amit, Luba Frolov, Elena Ovcharenko, Itzchak Angel, Moussa B. H. Youdim, Ofer Binah
Publikováno v:
PLoS ONE, Vol 8, Iss 6 (2013)
Externí odkaz:
https://doaj.org/article/dd182bbe221d422c884a954cc4cff70f
Autor:
Yaron D Barac, Orit Bar-Am, Esti Liani, Tamar Amit, Luba Frolov, Elena Ovcharenko, Itzchak Angel, Moussa B H Youdim, Ofer Binah
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e47890 (2012)
TVP1022, the S-enantiomer of rasagiline (Azilect®) (N-propargyl-1R-aminoindan), exerts cyto/cardio-protective effects in a variety of experimental cardiac and neuronal models. Previous studies have demonstrated that the protective activity of TVP102
Externí odkaz:
https://doaj.org/article/5f118b38e1ff4e3085d81f99839f6506
Autor:
Iris Alchanati, Carmit Teicher, Galit Cohen, Vivian Shemesh, Haim M Barr, Philippe Nakache, Danny Ben-Avraham, Anna Idelevich, Itzchak Angel, Nurit Livnah, Shmuel Tuvia, Yuval Reiss, Daniel Taglicht, Omri Erez
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8104 (2009)
The topoisomerases Top1, Top2alpha and Top2beta are important molecular targets for antitumor drugs, which specifically poison Top1 or Top2 isomers. While it was previously demonstrated that poisoned Top1 and Top2beta are subject to proteasomal degra
Externí odkaz:
https://doaj.org/article/24ff6b8faf1d447e8f52e8ce72cd3b5e
Autor:
Shemy Carasso, Eytan Malits, Moussa B.H. Youdim, Ofer Binah, Noa Bachner-Hinenzon, Rona Shofti, Yaron D. Barac, David Meerkin, Itzchak Angel, Offir Ertracht, Zaid Abassi, Assaf Malka
Publikováno v:
Journal of Cardiovascular Pharmacology. 66:214-222
BACKGROUND The current cornerstone treatment of myocardial infarction (MI) is restoration of coronary blood flow by means of thrombolytic therapy or primary percutaneous coronary intervention. However, reperfusion of ischemic myocardium can actually
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6a282b4b342acfea455d0f063b6ad75
https://doi.org/10.1097/fjc.0000000000000267
https://doi.org/10.1097/fjc.0000000000000267
Autor:
Joo-Yong Lee, Israel Shapiro, Jonathan E. Friedman, Firas M. Younis, Gilad Rosenberg, Arik Dahan, Revital Duvdevani, Eran Dvir, Amnon Hoffman, Shaul Raz, Itzchak Angel, Jae-Young Koh, Alex Kozak
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 318:1248-1256
Indomethacin has been suggested for the treatment of Alzheimer's disease (AD), but its use is limited by gastrointestinal and renal toxicity. To overcome this limitation, D-Pharm Ltd. (Rehovot, Israel) developed DP-155 (mixture of 1-steroyl and 1-pal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d15e08df3dbaac9f1508ce4ead7a983a
https://doi.org/10.1124/jpet.106.103184
https://doi.org/10.1124/jpet.106.103184
Publikováno v:
Neurobiology of Aging. 25:1315-1321
Metals such as zinc, copper and iron contribute to aggregation of amyloid-beta (Abeta) protein and deposition of amyloid plaques in Alzheimer's disease (AD). We examined whether the lipophilic metal chelator DP-109 inhibited these events in aged fema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d8c7fc7dfa25e28d2482e3d47171cb9
https://doi.org/10.1016/j.neurobiolaging.2004.01.005
https://doi.org/10.1016/j.neurobiolaging.2004.01.005
Autor:
Sarina Striem, Alex Kozak, Adina Bar, Galia Taler, Tammy Horovitz, Gilad Rosenberg, Dalia Resnitsky, Jonathan E. Friedman, Michael Krakovsky, Itzchak Angel
Publikováno v:
Drug Development Research. 56:300-309
Disturbance in metallochemical reactions and metal-protein association are associated with chronic neurodegenerative conditions, such as Alzheimer's and Parkinson's disease, as well as with neurodegeneration triggered by acute cerebral ischaemia. Man
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fb86a53616910cefa81bb1e3a8f72ad
https://doi.org/10.1002/ddr.10083
https://doi.org/10.1002/ddr.10083
Publikováno v:
European Journal of Pharmacology. 353:289-296
The present study characterized the rat colonic secretory response to 5-hydroxytryptamine (5-HT) and determined alterations in this response following stress. 5-HT stimulated rat colonic short-circuit current in a concentration-dependent fashion (pD2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a749e0b701f6ab96888826916cc4e1c
https://doi.org/10.1016/s0014-2999(98)00420-8
https://doi.org/10.1016/s0014-2999(98)00420-8
Publikováno v:
Life Sciences. 63:169-176
This study was undertaken in order to establish the alpha1-antagonist effects of alfuzosin on phenylephrine-induced increases in urethral and arterial blood pressures at 1 and 6 hours post dosing (10 mg/kg, p.o.). At each time, plasma and prostatic c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14bbc6edb74d823cbd53ba92eb4e9929
https://doi.org/10.1016/s0024-3205(98)00257-4
https://doi.org/10.1016/s0024-3205(98)00257-4
Publikováno v:
Life Sciences. 62:839-852
The effects of the alpha2-adrenoceptor antagonist SL84.0418 and its two enantiomers, (+) deriglidole and (-)SL86.0714 on glucose and insulin levels were examined in mice and in neonatal streptozotocin-induced diabetic rats. It was recently demonstrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48b2ad06d2d078de464a263ddf450da9
https://doi.org/10.1016/s0024-3205(97)01186-7
https://doi.org/10.1016/s0024-3205(97)01186-7