Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Itzcóatl A, Gómez"'
Autor:
Cleo Kontoravdi, Karen M. Polizzi, Stuart M. Haslam, Ioscani Jimenez del Val, Itzcóatl A. Gómez, Roberto Donini, Pavlos Kotidis, Masue Marbiah
Recombinant monoclonal antibodies bind specific molecular targets and, subsequently, induce an immune response or inhibit the binding of other ligands. However, monoclonal antibody functionality and half-life may be reduced by the type and distributi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e382a6890fa515ae8d929522c4ed86c2
http://hdl.handle.net/10044/1/97896
http://hdl.handle.net/10044/1/97896
Autor:
Pavlos, Kotidis, Masue, Marbiah, Roberto, Donini, Itzcóatl A, Gómez, Ioscani Jimenez, Del Val, Stuart M, Haslam, Karen M, Polizzi, Cleo, Kontoravdi
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2370
The impact of the glycan distribution on the in vivo function and half-life of monoclonal antibodies has long motivated the genetic engineering of producer cells to achieve structures that enhance efficacy, safety and stability. To facilitate glycoen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0b6cdc781742fac744d69b123d41e459
https://pubmed.ncbi.nlm.nih.gov/34611868
https://pubmed.ncbi.nlm.nih.gov/34611868
Autor:
Pavlos Kotidis, Karen M. Polizzi, Ioscani Jimenez del Val, Cleo Kontoravdi, Stuart M. Haslam, Itzcóatl A Gómez, Masue Marbiah, Roberto Donini
Publikováno v:
Glycosylation ISBN: 9781071616840
The impact of the glycan distribution on the in vivo function and half-life of monoclonal antibodies has long motivated the genetic engineering of producer cells to achieve structures that enhance efficacy, safety and stability. To facilitate glycoen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f849a58cc56ce81834fc0ba029cf599e
https://doi.org/10.1007/978-1-0716-1685-7_7
https://doi.org/10.1007/978-1-0716-1685-7_7
Publikováno v:
Biochemical Engineering Journal. 132:244-254
Centrifugation and microfiltration are the most commonly used steps for initial recovery of recombinant glycoproteins. However, such operations have significant drawbacks at large-scales. Accordingly, the use of flocculants was studied here as an alt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67b4dd1e79def1f954ae3afedac01de6
https://doi.org/10.1016/j.bej.2018.01.027
https://doi.org/10.1016/j.bej.2018.01.027