Zobrazeno 1 - 10
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pro vyhledávání: '"Iturriaga-Vásquez P"'
Akademický článek
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Autor:
Amaury Farías-Cea, Cristóbal Leal, Martín Hödar-Salazar, Erica Esparza, Luis Martínez-Duran, Irma Fuentes, Patricio Iturriaga-Vásquez
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 10635 (2023)
Anxiety is a serious mental disorder, and recent statistics have determined that 35.12% of the global population had an anxiety disorder during the COVID-19 pandemic. A mechanism associated with anxiolytic effects is related to nicotinic acetylcholin
Externí odkaz:
https://doaj.org/article/0442d3abed534c7586684830ac27c72c
Autor:
Gabriel Gálvez, Juan Pablo González-Gutiérrez, Martín Hödar-Salazar, Ramón Sotomayor-Zárate, María Elena Quintanilla, María Elena Quilaqueo, Mario Rivera-Meza, Patricio Iturriaga-Vásquez
Publikováno v:
Biomedicines, Vol 10, Iss 7, p 1482 (2022)
Alcoholism is a worldwide public health problem with high economic cost and which affects health and social behavior. It is estimated that alcoholism kills 3 million people globally, while in Chile it is responsible for around 9 thousand deaths per y
Externí odkaz:
https://doaj.org/article/a565a0fff56343d18f5394f15368098d
Autor:
Gabriel Quiroz, Ramón Sotomayor-Zárate, Juan Pablo González-Gutierrez, Franco Vizcarra, Felipe Moraga, Isabel Bermudez, Miguel Reyes-Parada, María Elena Quintanilla, Diego Lagos, Mario Rivera-Meza, Patricio Iturriaga-Vásquez
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Brain nicotinic acetylcholine receptors (nAChRs), a heterogeneous family of pentameric acetylcholine-gated cation channels, have been suggested as molecular targets for the treatment of alcohol abuse and dependence. Here, we examined the effect of th
Externí odkaz:
https://doaj.org/article/205bae793a904fdc952bd2c097feaf04
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Autor:
Christopher Cerda-Cavieres, Gabriel Quiroz, Patricio Iturriaga-Vásquez, Julio Rodríguez-Lavado, Jazmín Alarcón-Espósito, Claudio Saitz, Carlos D. Pessoa-Mahana, Hery Chung, Ramiro Araya-Maturana, Jaime Mella-Raipán, David Cabezas, Claudia Ojeda-Gómez, Miguel Reyes-Parada, Hernán Pessoa-Mahana
Publikováno v:
Molecules, Vol 25, Iss 20, p 4614 (2020)
A series of 27 compounds of general structure 2,3-dihydro-benzo[1,4]oxazin-4-yl)-2-{4-[3-(1H-3indolyl)-propyl]-1-piperazinyl}-ethanamides, Series I: 7(a–o) and (2-{4-[3-(1H-3-indolyl)-propyl]-1-piperazinyl}-acetylamine)-N-(2-morfolin-4-yl-ethyl)-fl
Externí odkaz:
https://doaj.org/article/ad09736e79234c8b9134bb4e5a5f08f2
Autor:
Franco Viscarra, Juan González-Gutierrez, Erica Esparza, Carla Figueroa, Pablo Paillali, Martin Hödar-Salazar, Camilo Cespedes, Gabriel Quiroz, Ramón Sotomayor-Zárate, Miguel Reyes-Parada, Isabel Bermúdez, Patricio Iturriaga-Vásquez
Publikováno v:
Molecules, Vol 25, Iss 13, p 2998 (2020)
Zebrafish is becoming a popular animal model in neuropharmacology and drug discovery, mainly due to its ease of handling and low costs involved in maintenance and experimental work. This animal displays a series of complex behaviours that makes it us
Externí odkaz:
https://doaj.org/article/622ae8bd1515461886632e234ff604cf
Autor:
Gabriel Núñez-Vivanco, Angélica Fierro, Pablo Moya, Patricio Iturriaga-Vásquez, Miguel Reyes-Parada
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200637 (2018)
The study of binding site similarities can be relevant to understand the interaction of different drugs at several molecular targets. The increasing availability of protein crystal structures and the development of novel algorithms designed to evalua
Externí odkaz:
https://doaj.org/article/7b5a8916c3d64e4f868707fda299f4de
Autor:
Juan Pablo González-Gutiérrez, Hernán Armando Pessoa-Mahana, Patricio Ernesto Iturriaga-Vásquez, Miguel Iván Reyes-Parada, Nicolas Esteban Guerra-Díaz, Martin Hodar-Salazar, Franco Viscarra, Pablo Paillali, Gabriel Núñez-Vivanco, Marcos Antonio Lorca-Carvajal, Jaime Mella-Raipán, María Carolina Zúñiga
Publikováno v:
Molecules, Vol 24, Iss 20, p 3808 (2019)
Nicotinic acetylcholine receptors (nAChRs), serotonin transporters (SERT) and dopamine transporters (DAT) represent targets for the development of novel nicotinic derivatives acting as multiligands associated with different health conditions, such as
Externí odkaz:
https://doaj.org/article/54b84d602fb54176b3b2e06d275c291c
Autor:
Juan Pablo Gonzalez-Gutierrez, Martin Hodar, Franco Viscarra, Pablo Paillali, Nicolás Guerra-Díaz, Hernán Pessoa-Mahana, Juan José Hernández-Morantes, Horacio Pérez-Sánchez, Isabel Bermúdez, Miguel Reyes-Parada, Patricio Iturriaga-Vásquez
Publikováno v:
Molecules, Vol 24, Iss 15, p 2684 (2019)
Neuronal α4β2 nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels (LGIC) that have been implicated in nicotine addiction, reward, cognition, pain disorders, anxiety, and depression. Nicotine has been widely used as a template f
Externí odkaz:
https://doaj.org/article/838d686b3ffa4812a112c5c2aef46ae7