Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Itsuko Kimura-Takagi"'
Autor:
Motohiro Nonaka, Hideaki Mabashi-Asazuma, Donald L Jarvis, Kazuhiko Yamasaki, Tomoya O Akama, Masato Nagaoka, Toshio Sasai, Itsuko Kimura-Takagi, Yoichi Suwa, Takashi Yaegashi, Chun-Teng Huang, Chizuko Nishizawa-Harada, Michiko N Fukuda
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0241157 (2021)
We previously reported that IF7 peptide, which binds to the annexin A1 (ANXA1) N-terminus, functions as a tumor vasculature-targeted drug delivery vehicle after intravenous injection. To enhance IF7 stability in vivo, we undertook mirror-image peptid
Externí odkaz:
https://doaj.org/article/5d129291cb2948fdaf1c7fd0544d7567
Autor:
Chun-Teng Huang, Minoru Fukuda, Yoichi Suwa, Toshio Sasai, Motohiro Nonaka, Michiko N. Fukuda, Kazuhiro Sugihara, Tomoya O. Akama, Kazuhiko Yamasaki, Jun Nakayama, Itsuko Kimura-Takagi, Takashi Yaegashi, Jiunn Chern Yeh, Hideaki Mabashi-Asazuma, Chizuko Nishizawa-Harada, Alexandre Rosa Campos, Misa Suzuki-Anekoji, Toshiaki K. Shibata, Masato Nagaoka, Donald L. Jarvis
Publikováno v:
British Journal of Cancer
Background Annexin A1 is expressed specifically on the tumour vasculature surface. Intravenously injected IF7 targets tumour vasculature via annexin A1. We tested the hypothesis that IF7 overcomes the blood–brain barrier and that the intravenously
Autor:
Kazuhiko Yamasaki, Takashi Yaegashi, Michiko N. Fukuda, Hideaki Mabashi-Asazuma, Itsuko Kimura-Takagi, Motohiro Nonaka, Masato Nagaoka, Toshio Sasai, Chizuko Nishizawa-Harada, Chun-Teng Huang, Yoichi Suwa, Tomoya O. Akama, Donald L. Jarvis
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0241157 (2021)
PLoS ONE
PLoS ONE
IF7 peptide, which binds to the annexin A1 (ANXA1) N-terminal domain, functions as a tumor vasculature-targeted drug delivery vehicle after intravenous injection. To enhance IF7 stability in vivo, we undertook mirror-image peptide phage display using
Autor:
Sadao Ueyama, Teruo Yokokura, Ritsuo Aiyama, Itsuko Kimura-Takagi, Hideyuki Shibata, Shusuke Hashimoto, Masato Nagaoka
Publikováno v:
BioFactors. 12:267-274
The nutritional value of marine algae has long been recognized in the Orient, but in the Western world, the use of seaweeds for human consumption is limited: they exist as additives and so-called health foods. In contrast, more seaweed than ever befo
Autor:
Teruo Yokokura, Masato Nagaoka, Sadao Ueyama, Hideyuki Shibata, Haruji Sawada, Shusuke Hashimoto, Itsuko Kimura-Takagi
Publikováno v:
Journal of Nutritional Science and Vitaminology. 45:325-336
We studied the inhibitory effect of Cladosiphon fucoidan on the attachment of Helicobacter pylori (H. pylori), a gastroduodenal pathogen, to human gastric cell lines. The bacterial binding in these cell lines was inhibited more by Cladosiphon fucoida
Autor:
Masato Nagaoka, Takashi Makino, Hideyuki Shibata, Teruo Yokokura, Kazumasa Kimura, Sadao Ueyama, Itsuko Kimura-Takagi, Shusuke Hashimoto, Ritsuo Aiyama
Publikováno v:
Glycoconjugate Journal. 16:19-26
A structural study was carried out on a fucoidan isolated from the brown seaweed Cladosiphon okamuranus. The polysaccharide contained fucose, glucuronic acid and sulfate in a molar ratio of about 6.1 : 1.0 : 2.9. The results of Smith degradation show
Autor:
Hideyuki Shibata, Itsuko Kimura-Takagi, Sadao Ueyama, Teruo Yokokura, Masato Nagaoka, Shusuke Hashimoto, Ritsuo Aiyama, Masahiko Iha
Publikováno v:
BioFactors (Oxford, England). 11(4)
To elucidate the anti-ulcer potential of Cladosiphon fucoidan, anti-peptic activity, bFGF stabilizing activity and inflammatory properties of this and related substances were investigated. Anti-peptic activity was observed with this and other sulfate