Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Itsuki Shinbo"'
Autor:
Yoshio Terada, Yuriko Katsushima, Daniel G. Bichet, Marie-Françoise Arthus, Michio Kuwahara, Michèle Lonergan, Toru Ooeda, Itsuki Shinbo, Eishin Ogawa, Sei Sasaki, Fumiaki Marumo, Shinichi Uchida, Kazuyuki Iwai, T. Mary Fujiwara, Takashi Igarashi
Publikováno v:
The American Journal of Human Genetics. 69:738-748
The vasopressin-regulated water channel aquaporin-2 (AQP2) is known to tetramerize in the apical membrane of the renal tubular cells and contributes to urine concentration. We identified three novel mutations, each in a single allele of exon 4 of the
Autor:
Michio Kuwahara, Yoshio Terada, Itsuki Shinbo, Kazunori Sato, Fumiaki Marumo, Tomiki Asai, Sei Sasaki
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1517:107-112
A genome project for the species Caenorhabditis elegans has demonstrated the presence of eight cDNAs belonging to the major intrinsic protein (MIP) family. We previously characterized one of these cDNAs known as C01G6.1. C01G6.1 was confirmed to be a
Publikováno v:
Biochemistry. 38(49)
Aquaporin-2 (AQP2), a vasopressin-regulated water channel, plays a major role in urinary concentration. AQP2 and the major intrinsic protein (MIP) of lens fiber are highly homologous (58% amino acid identity) and share a topology of six transmembrane
Autor:
Sei Sasaki, Itsuki Shinbo, Michihiro Kasahara, Kazushi Yamauchi, Kiyohide Fushimi, Fumiaki Marumo
Publikováno v:
The American journal of physiology. 277(5)
Mutations of aquaporin-2 (AQP2) vasopressin water channel cause nephrogenic diabetes insipidus (NDI). It has been suggested that impaired routing of AQP2 mutants to the plasma membrane causes the disease; however, no determinations have been made of
Autor:
Yumi Yamashita, Kazushi Yamauchi, Itsuki Shinbo, Kiyohide Fushimi, Fumiaki Marumo, Sei Sasaki
Publikováno v:
Kidney International. (1):164-171
Effects of missense mutations on rat aquaporin-2 in LLC-PK1 porcine kidney cells. Background Mutations in the aquaporin-2 (AQP2) gene have been found in families with nephrogenic diabetes insipidus (NDI), but the pathophysiological mechanisms of how