Zobrazeno 1 - 10
of 180
pro vyhledávání: '"Itsik PE'ER"'
Autor:
Raiyan R. Khan, Rafael F. Guerrero, Ronald J. Wapner, Matthew W. Hahn, Anita Raja, Ansaf Salleb-Aouissi, William A. Grobman, Hyagriv Simhan, Robert M. Silver, Judith H. Chung, Uma M. Reddy, Predrag Radivojac, Itsik Pe’er, David M. Haas
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Adverse pregnancy outcomes (APOs) affect a large proportion of pregnancies and represent an important cause of morbidity and mortality worldwide. Yet the pathophysiology of APOs is poorly understood, limiting our ability to prevent and treat
Externí odkaz:
https://doaj.org/article/3d4e841d56df4a31ba7c73f2e48f8b88
Autor:
Celine M. Schreidah, Emily R. Gordon, Oluwaseyi Adeuyan, Caroline Chen, Brigit A. Lapolla, Joshua A. Kent, George Bingham Reynolds, Lauren M. Fahmy, Chunhua Weng, Nicholas P. Tatonetti, Herbert S. Chase, Itsik Pe’er, Larisa J. Geskin
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Skin cancer mortality rates continue to rise, and survival analysis is increasingly needed to understand who is at risk and what interventions improve outcomes. However, current statistical methods are limited by inability to synthesize multiple data
Externí odkaz:
https://doaj.org/article/645da4e01a6e4dfe8d2990e3a7d08497
Autor:
Celine M. Schreidah, BS, George Bingham Reynolds, MS, Lauren M. Fahmy, BS, Richard D. Carvajal, MD, Maarten H. Vermeer, MD, Sean Whittaker, MD, Itsik Pe’er, PhD, Larisa J. Geskin, MD
Publikováno v:
JAAD International, Vol 12, Iss , Pp 24-31 (2023)
Externí odkaz:
https://doaj.org/article/c29058b159354fdd87c91ab23cefb753
Publikováno v:
mSystems, Vol 6, Iss 6 (2021)
ABSTRACT The gut microbiome is spatially heterogeneous, with environmental niches contributing to the distribution and composition of microbial populations. A recently developed mapping technology, MaPS-seq, aims to characterize the spatial organizat
Externí odkaz:
https://doaj.org/article/002c627ee4ac45d48bc9441271580062
Autor:
Jie Yuan, Hengrui Xing, Alexandre Louis Lamy, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Todd Lencz, Itsik Pe'er
Publikováno v:
PLoS Genetics, Vol 16, Iss 10, p e1009158 (2020)
[This corrects the article DOI: 10.1371/journal.pgen.1009015.].
Externí odkaz:
https://doaj.org/article/e0513c2b484241078e66124a6bdcfee9
Autor:
Jie Yuan, Henry Xing, Alexandre Louis Lamy, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Todd Lencz, Itsik Pe'er
Publikováno v:
PLoS Genetics, Vol 16, Iss 9, p e1009015 (2020)
Evidence from both GWAS and clinical observation has suggested that certain psychiatric, metabolic, and autoimmune diseases are heterogeneous, comprising multiple subtypes with distinct genomic etiologies and Polygenic Risk Scores (PRS). However, the
Externí odkaz:
https://doaj.org/article/6957cbd7c9034e58abce51f27d059b13
Autor:
Nenad Macesic, Oliver J. Bear Don’t Walk, Itsik Pe’er, Nicholas P. Tatonetti, Anton Y. Peleg, Anne-Catrin Uhlemann
Publikováno v:
mSystems, Vol 5, Iss 3 (2020)
ABSTRACT Polymyxins are used as treatments of last resort for Gram-negative bacterial infections. Their increased use has led to concerns about emerging polymyxin resistance (PR). Phenotypic polymyxin susceptibility testing is resource intensive and
Externí odkaz:
https://doaj.org/article/3abeb846df064f22989250bc86e19c45
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 5, p e1007917 (2020)
Dynamic changes in microbial communities play an important role in human health and disease. Specifically, deciphering how microbial species in a community interact with each other and their environment can elucidate mechanisms of disease, a problem
Externí odkaz:
https://doaj.org/article/5240174de84743169bdf1c704a15c5ff
Autor:
Cameron Palmer, Itsik Pe'er
Publikováno v:
PLoS Genetics, Vol 13, Iss 7, p e1006916 (2017)
Genome-wide association studies (GWAS) have identified hundreds of SNPs responsible for variation in human quantitative traits. However, genome-wide-significant associations often fail to replicate across independent cohorts, in apparent inconsistenc
Externí odkaz:
https://doaj.org/article/036fffa4414f4787969636e8fe466d97
Publikováno v:
PLoS Genetics, Vol 13, Iss 4, p e1006644 (2017)
The Ashkenazi Jewish (AJ) population is important in genetics due to its high rate of Mendelian disorders. AJ appeared in Europe in the 10th century, and their ancestry is thought to comprise European (EU) and Middle-Eastern (ME) components. However,
Externí odkaz:
https://doaj.org/article/29eba63f9f564beca850b03a0087fc5d