Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Itsaso Hormaeche"'
Autor:
Begoña Ugarte-Uribe, Itsaso Hormaeche, Itziar Alkorta, Félix M. Goñi, Rosa L. Segura, Ana J. Vecino, Fernando de la Cruz, Sandra Águila
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Bacterial conjugative systems code for an essential membrane protein that couples the relaxosome to the DNA transport apparatus, called type IV couplingprotein (T4CP). TrwB is the T4CP of the conjugative plasmid R388. In earlier work we found that th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8af7cf86187a11e729a6fd8c322d9b4d
Autor:
Julien Ablain, David Grimwade, Sergei Doulatov, John E. Dick, Charuta Ambardekar, Jared M. Flatow, Ken I. Mills, Melanie J. McConnell, Magdalena Leiva, Jonathan D. Licht, Kim L. Rice, Itsaso Hormaeche
Publikováno v:
Blood. 114:5499-5511
The t(11;17)(q23;q21) translocation is associated with a retinoic acid (RA)–insensitive form of acute promyelocytic leukemia (APL), involving the production of reciprocal fusion proteins, promyelocytic leukemia zinc finger–retinoic acid receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ed5205abb4363f709f78d1927fd2de5
https://doi.org/10.1182/blood-2009-03-206524
https://doi.org/10.1182/blood-2009-03-206524
Publikováno v:
Oncogene. 26:6697-6714
The molecular processes governing hematopoiesis involve the interplay between lineage-specific transcription factors and a series of epigenetic tags, including DNA methylation and covalent histone tail modifications, such as acetylation, methylation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a67ac31979950e707df13c10ccc7ff73
https://doi.org/10.1038/sj.onc.1210755
https://doi.org/10.1038/sj.onc.1210755
Autor:
Sarah Pierce, Jonathan D. Licht, Louise Howell, Philip A. Cole, Sarah Ivins, Arthur Zelent, Itsaso Hormaeche, Fabien Guidez, Marek Cebrat, Mark Isalan, Rhoda M. Alani, Melanie J. McConnell
Publikováno v:
Molecular and Cellular Biology. 25:5552-5566
Histone acetyltransferase (HAT) activities of proteins such as p300, CBP, and P/CAF play important roles in activation of gene expression. We now show that the HAT activity of p300 can also be required for down-regulation of transcription by a DNA bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb87e66a0f5e6a7e787b48614b0a8c4e
https://doi.org/10.1128/mcb.25.13.5552-5566.2005
https://doi.org/10.1128/mcb.25.13.5552-5566.2005
Autor:
Félix M. Goñi, Itsaso Hormaeche, Fernando de la Cruz, Itziar Alkorta, Fernando Moro, José M. Valpuesta
Publikováno v:
Journal of Biological Chemistry. 277:46456-46462
TrwB is an integral membrane protein linking the relaxosome to the DNA transport apparatus in plasmid R388 conjugation. Native TrwB has been purified in monomeric and hexameric forms, in the presence of dodecylmaltoside from overexpressing bacterial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46184ccca5b02e68818d429f2a9bde97
https://doi.org/10.1074/jbc.m207250200
https://doi.org/10.1074/jbc.m207250200
Publikováno v:
Therapeutic Targets: Modulation, Inhibition, and Activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0b59fd1ade8f326635630cb610f3245
https://doi.org/10.1002/9781118185537.ch11
https://doi.org/10.1002/9781118185537.ch11
Autor:
Jonathan D. Licht, Itsaso Hormaeche
Publikováno v:
Cancer cell. 11(6)
Oncogenic transcription factors such as PML-RARalpha, RUNX1-MTG8, and others work in large part by the recruitment of inhibitors of gene transcription to target promoters leading to aberrant repression of gene expression. PML-RARalpha, an archetypal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::038070fc1b62c1cde7eae83e4059763f
https://pubmed.ncbi.nlm.nih.gov/17560333
https://pubmed.ncbi.nlm.nih.gov/17560333
Autor:
Fernando de la Cruz, Itsaso Hormaeche, José Luis R. Arrondo, Itziar Alkorta, Félix M. Goñi, Ibon Iloro
Publikováno v:
The Journal of biological chemistry. 279(12)
TrwB is an integral membrane protein encoded by the conjugative plasmid R388. TrwB binds ATP and is essential for R388-directed bacterial conjugation. The protein consists of a cytosolic domain, which contains an ATP-binding site, and a transmembrane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ff9a7c8efd0b9c16edb89dc77682414
https://pubmed.ncbi.nlm.nih.gov/14699106
https://pubmed.ncbi.nlm.nih.gov/14699106
Publikováno v:
Blood. 112:198-198
As a result of the t(11;17) translocation in retinoic acid resistant subtype of acute promyelocytic leukemia (APL), the transcriptional repression domains of the Promyelocytic Leukemia Zinc Finger protein (PLZF) are fused to the ligand binding and DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eeb785bdb52d091dee94ab5da1a484b0
https://doi.org/10.1182/blood.v112.11.198.198
https://doi.org/10.1182/blood.v112.11.198.198
Autor:
Jonathan D. Licht, David Grimwade, John E. Dick, Melanie J. McConnell, Ken I. Mills, Kim L. Rice, Sergei Doulatov, Jared M. Flatow, Itsaso Hormaeche
Publikováno v:
Blood. 112:686-686
The t(11;17)(q23;q21) translocation is associated with a retinoic acid-insensitive form of acute promyelocytic leukemia (APL) involving the production of reciprocal fusion proteins PLZF-RARα and RARα-PLZF. These proteins mediate malignant transform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f71faca31aa1a6a088a34811a704c8d0
https://doi.org/10.1182/blood.v112.11.686.686
https://doi.org/10.1182/blood.v112.11.686.686