Solid-Phase Synthesis of Biaryl Cyclic Lipopeptides Derived from Arylomycins

Autor: Iteng Ng-Choi, Eduard Figueras, Àngel Oliveras, Lidia Feliu, Marta Planas

Publikováno v: ACS Omega, Vol 5, Iss 36, Pp 23401-23412 (2020)

Externí odkaz: https://doaj.org/article/c78a89deab634917a0b393f7d03491aa

Multivalent display of the antimicrobial peptides BP100 and BP143

Autor: Imma Güell, Rafael Ferre, Kasper K. Sørensen, Esther Badosa, Iteng Ng-Choi, Emilio Montesinos, Eduard Bardají, Lidia Feliu, Knud J. Jensen, Marta Planas

Publikováno v: Beilstein Journal of Organic Chemistry, Vol 8, Iss 1, Pp 2106-2117 (2012)

Carbohydrates are considered as promising templates for the display of multiple copies of antimicrobial peptides. Herein, we describe the design and synthesis of chimeric structures containing two or four copies of the antimicrobial peptides KKLFKKIL

Externí odkaz: https://doaj.org/article/8a5826f686ba4afa9dedad331d47bdab

Solid-phase synthesis of biaryl bicyclic peptides containing a 3-aryltyrosine or a 4-arylphenylalanine moiety

Autor: Àngel Oliveras, Iteng Ng-Choi, Lidia Feliu, Marta Planas

Publikováno v: Beilstein Journal of Organic Chemistry
Ng-Choi, Iteng Oliveras Rovira, Àngel Feliu Soley, Lídia Planas i Grabuleda, Marta 2019 Solid-phase synthesis of biaryl bicyclic peptides containing a 3-aryltyrosine or a 4-arylphenylalanine Beilstein Journal of Organic Chemistry 15 761 768
Beilstein Journal of Organic Chemistry, Vol 15, Iss 1, Pp 761-768 (2019)
Beilstein Journal of Organic Chemistry, 2019, vol. 15, p. 761-768
Articles publicats (D-Q)
DUGiDocs – Universitat de Girona
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A methodology for the solid-phase synthesis of biaryl bicyclic peptides containing a Phe-Phe, a Phe-Tyr or a Tyr-Tyr motif has been devised. This approach comprises two key steps. The first one involves the cyclization of a linear peptidyl resin cont

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6322f34dbfc0cfeedf9ad7de0ed5fef8
https://doi.org/10.3762/bjoc.15.72

Solid-phase synthesis of biaryl cyclic peptides containing a histidine-phenylalanine linkage

Autor: Marta Planas, Iteng Ng-Choi, Àngel Oliveras, Lidia Feliu

Publikováno v: © International Journal of Peptide Research and Therapeutics, 2020, vol. 26, p. 695-707
Articles publicats (D-Q)
Ng-Choi, Iteng Oliveras Rovira, Àngel Feliu Soley, Lídia Planas i Grabuleda, Marta 2020 Solid-phase synthesis of biaryl cyclic peptides containing a histidine-phenylalanine linkage International Journal of Peptide Research and Therapeutics 26 695 707
DUGiDocs – Universitat de Girona
instname

The feasibility of the solid-phase intramolecular 4(5)-arylation of a histidine residue to obtain biaryl cyclic peptides bearing a His-Phe linkage was established. The synthetic strategy involved the preparation of a linear peptidyl resin incorporati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91053c08480d47fe7527ee424f9eb252
http://hdl.handle.net/10256/18663

A nucleus-directed bombesin derivative for targeted delivery of metallodrugs to cancer cells

Autor: Gustavo Espino, Marta Planas, Félix A. Jalón, Blanca R. Manzano, Lidia Feliu, Anna Massaguer, Iteng Ng-Choi, Maria Ángeles Varela Martínez, Rafael de Llorens, Sílvia Barrabés

Publikováno v: Journal of Inorganic Biochemistry. 212:111214

We have synthesized a set of bombesin derivatives with the aim of exploring their tumor targeting properties to deliver metal-based chemotherapeutics into cancer cells. Peptide QRLGNQWAVGHLL-NH2 (BN3) was selected based on its high internalization in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::506aadfd10d36b7f892ceadc085dc681
https://doi.org/10.1016/j.jinorgbio.2020.111214